From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Dipeptidase 3 (DPEP3 ) is a
protein that in humans is encoded by the DPEP3
gene .
[5]
This gene encodes a membrane-bound glycoprotein from the family of
dipeptidases (EC 3.4.13.19) involved in hydrolytic metabolism of various
dipeptides , including
penem and
carbapenem
beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family,
DPEP2 . Alternatively spliced transcript variants that encode different isoforms have been found for this gene.
[6]
References
Further reading
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Sabatti C , Service SK, Hartikainen AL, et al. (2009).
"Genome-wide association analysis of metabolic traits in a birth cohort from a founder population" . Nat. Genet . 41 (1): 35–46.
doi :
10.1038/ng.271 .
PMC
2687077 .
PMID
19060910 .
Clark HF, Gurney AL, Abaya E, et al. (2003).
"The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment" . Genome Res . 13 (10): 2265–70.
doi :
10.1101/gr.1293003 .
PMC
403697 .
PMID
12975309 .
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006).
"Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55–65.
doi :
10.1101/gr.4039406 .
PMC
1356129 .
PMID
16344560 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2002).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
This article incorporates text from the
United States National Library of Medicine , which is in the
public domain .
Activity Regulation Classification Kinetics Types