Basaloid follicular hamartoma is a cutaneous condition characterized as distinctive benign adnexal tumor that has several described variants.[1]: 675 It manifest as small tan or brown coloured
papules in the trunk, pubic area, face, scalp, and axilla.
Basaloid follicular hamartoma is associated with a variety of disorders and is caused by mutation in the
PTCH gene. The diagnosis is made based of histopathological examination.
Signs and symptoms
Basaloid follicular hamartoma manifests as multiple 1- to 2mm tan-to-brown-colored
papules located on the pubic area, trunk, axilla, scalp, and face.[2]
Causes
Basaloid follicular hamartoma can be hereditary or acquired.[3]
Basaloid follicular hamartoma is caused by a mutation in the chromosome 9q23 patch (PTCH) gene, which is also the gene responsible for
nevoid basal cell carcinoma syndrome.[4]
Diagnosis
The diagnosis of basaloid follicular hamartoma lesions requires a histopathological investigation.[2] Histopathological features include basaloid
epithelial cells in the papillary
dermis form multifocal islands and branching cords, some of which are attached to the epidermis and dilated
hair follicles.[5]
Treatment
Various interventions, including photodynamic therapy, carbon dioxide laser, and surgery, have been suggested.[5]