| Giant solitary trichoepithelioma | |
|---|---|
| Specialty |
Dermatology,
oncology
 |
Giant solitary trichoepithelioma is a cutaneous condition characterized by a skin lesion that may be up to several centimetres in diameter. [1]: 672
Signs and symptoms
Giant solitary trichoepithelioma primarily affects the perianal and groin region. [2] They typically measure a few centimeters in diameter and rarely reach 2 to 3 cm. [3]
Diagnosis
Giant solitary trichoepithelioma is distinguished histologically by a dermal or subcutaneous tumor made up of basophilic cells grouped in solid, adenoid, or lace-like clusters. The cells have a sparse cytoplasm and a darkly pigmented nucleus, and the tumor islands exhibit the typical peripheral cell palisading. Papillary bodies and trichilemmal keratinization in horn cysts are indicative of a solid diagnosis, however they are not always present. Failures to develop papillary mesenchyme are represented by papillary bodies. [4]
Treatment
The preferred course of treatment is either radiosurgical ablation or surgical excision, with or without a flap. [4]
See also
References
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ^ Teli, Bhavuray; Thrishuli, P. B.; Santhosh, R.; Amar, D. N.; Rajpurohit, Shravan (2015). "Giant solitary trichoepithelioma". South Asian Journal of Cancer. 04 (1). Georg Thieme Verlag KG: 041–044. doi: 10.4103/2278-330x.149951. ISSN 2278-330X. PMC 4382785. PMID 25839021.
- ^ Genc, Selahattin; Sirin Ugur, Seher; Arslan, Ilker Burak; Demir, Ahmet; Tuhanioglu, Birgul; Kuskonmaz, Ibrahim; Eruyar, Tugrul; Selcuk, Adin (2012). "A Giant Solitary Trichoepithelioma Originating from the Auricle". Dermatologic Surgery. 38 (9): 1527–1528. doi: 10.1111/j.1524-4725.2012.02483.x. ISSN 1076-0512. PMID 22691160.
- ^ a b Swaroop, MukundaRanga; Sathyanarayana, BelagolaDassegowda; Chaurasia, PriyankaKumari; Devaraj, Yogesh; Dukkipati, Monica; Sajid, Aneesa (2017). "Giant solitary trichoepithelioma over the nose". Indian Journal of Dermatopathology and Diagnostic Dermatology. 4 (1): 17. doi: 10.4103/ijdpdd.ijdpdd_65_16. ISSN 2349-6029.
Further reading
- Martinez, Carlos Augusto Real; Priolli, Denise Gonçalves; Piovesan, Helenice; Waisberg, Jaques (2004). "Nonsolitary Giant Perianal Trichoepithelioma With Malignant Transformation Into Basal Cell Carcinoma: Report of a Case and Review of the Literature". Diseases of the Colon & Rectum. 47 (5). Ovid Technologies (Wolters Kluwer Health): 773–777. doi: 10.1007/s10350-003-0104-8. ISSN 0012-3706. PMID 15073659.
- Bubna, AdityaKumar; Patil, NitinKrishna; Hussain, Seeba; Singh, Neha (2022). "Giant solitary trichoepithelioma: A diagnosis of exclusion". International Journal of Trichology. 14 (6). Medknow: 221–223. doi: 10.4103/ijt.ijt_9_21. ISSN 0974-7753. PMC 10075344. PMID 37034549.