An eccrine nevus is an extremely rare cutaneous condition that,
histologically, is characterized by an increase in size or number of
eccrine secretory coils.[1]: 774 Hyperhidrosis is the most common symptom. It can present as discoloured
nodules,
papules, or plaques. Eccrine nevus mostly affects the extremities. Eccrine nevus are diagnosed based of
histology. Treatment includes surgical excision or topical medications.
Signs and symptoms
The clinical signs of eccrine nevus might vary, involving a single nodular lesion or a broad patch encompassing the majority of the trunk.[2] Discolored
nodules,
papules, and plaques may also be present. The most often reported symptom, though not always present, is
hyperhidrosis.[3] The majority of eccrine nevi are found iin the extremities, with a preference for the
forearms.[4]
Causes
The cause of eccrine nevus is uncertain.[3] The postulated pathogenic variables include congenital abnormalities in
embryogenesis, trauma, and stress, although none have been verified.[5]
Diagnosis
Eccrine nevi are identified histologically, with findings indicating just an increase in the size and/or number of structurally normal
eccrine glands. However, there have been cases reported with structural abnormalities, including adenomatous alterations, pseudobasaloid cell nests, and twisted ducts.[6]
Treatment
The course of treatment for eccrine nevus is determined by the patient's preferences, associated symptoms, and the extent of the lesion.[4] Surgical excision may be the best course of action when the lesion is tiny. Conversely, topical therapies such
botulinum toxin or
anticholinergic medicines may be used when localized
hyperhidrosis coexists with a big skin lesion.[7]
^Tempark, T.; Shwayder, T. (2012-12-18). "Mucinous eccrine naevus: case report and review of the literature". Clinical and Experimental Dermatology. 38 (1). Oxford University Press (OUP): 1–6.
doi:
10.1111/ced.12034.
ISSN0307-6938.
PMID23252751.