Annular elastolytic giant-cell granuloma (also known as "Giant cell elastophagocytosis,"[1] "Meischer's granuloma,"[2] "Miescher's granuloma of the face"[1]) is a cutaneous condition characterized histologically by a
dermal infiltrate of
macrophages.[1][2]: 706
Signs and symptoms
The most common presentation of annular elastolytic giant-cell granuloma is one or more annular or ring-shaped patches with elevated borders,
atrophy, and central
hypopigmentation. Generalized papular lesions may also be observed.[3][4] Although it sporadically affects covered areas as well, annular elastolytic giant-cell granuloma is generally thought to be a disease that primarily affects sun-exposed areas.[5][6]
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abcRapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby.
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abJames, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier.
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^Özkaya-Bayazit; Büyükbabani̇; Baykal; Öztürk; Okçu; Soyer (1999). "Annular elastolytic giant cell granuloma: sparing of a burn scar and successful treatment with chloroquine". British Journal of Dermatology. 140 (3). Oxford University Press (OUP): 525–530.
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PMID10233280.
S2CID23145183.
^Rongioletti, F.; Baldari, M.; Burlando, M.; Parodi, A. (2010). "Papular elastolytic giant cell granuloma: report of a case associated with monoclonal gammopathy and responsive to topical tacrolimus". Clinical and Experimental Dermatology. 35 (2). Oxford University Press (OUP): 145–148.
doi:
10.1111/j.1365-2230.2008.03129.x.
ISSN0307-6938.
PMID19508563.
S2CID19674767.