| Paraneoplastic acrokeratosis | |
|---|---|
| Other names | Acrokeratosis paraneoplastica of Bazex and Acrokeratosis neoplastica) [1] |
| Specialty |
Dermatology
 |
Paraneoplastic acrokeratosis, or Bazex syndrome is a cutaneous condition characterized by psoriasiform changes of hands, feet, ears, and nose, with involvement of the nails and periungual tissues being characteristic and indistinguishable from psoriatic nails. The condition is associated with carcinomas of the upper aerodigestive tract. [2]: 665
History
A case was first reported by Henri Gougerot and C. Grupper in 1922. [3] [4] Andre Bazex described it as a paraneoplastic syndrome in 1965. [3] [5]
See also
- List of cutaneous conditions
- Nail anatomy
- List of cutaneous conditions associated with increased risk of nonmelanoma skin cancer
References
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
- ^ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
- ^ a b Chiesa-Fuxench, Zelma C.; Ramírez, Liliana; Sánchez, Néstor P. (2011). "Cutaneous manifestations of internal malignancy and paraneoplastic syndromes". In Sánchez, Néstor P. (ed.). Atlas of Dermatology in Internal Medicine. New York: Springer Science & Business Media. p. 66. ISBN 978-1-4614-0687-7.
- ^ Gougerot, H. and Grupper, C., (1922). Dermatose érythémato-squameuse avec hyperkératose palmoplantaire, porectasies digitales et cancer de la langue latent. Paris Med, 43, pp.234-237
- ^ Bazex, A.; Griffiths, A. (September 1980). "Acrokeratosis paraneoplastica--a new cutaneous marker of malignancy". The British Journal of Dermatology. 103 (3): 301–306. doi: 10.1111/j.1365-2133.1980.tb07248.x. ISSN 0007-0963. PMID 7000146.