| 3β(or 20α)-hydroxysteroid dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.210 | ||||||||
| CAS no. | 82869-26-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 3-β(or 20-α)-hydroxysteroid dehydrogenase ( EC 1.1.1.210) is an enzyme that catalyzes the chemical reaction
- 5α-androstan-3β,17β-diol + NADP+ 17β-hydroxy-5α-androstan-3-one + NADPH + H+
This enzyme possesses the combined activities of the 3-β-hydroxysteroid dehydrogenase/Δ-5-4 isomerase and 20-α-hydroxysteroid dehydrogenase enzymes. [1]
References
- ^ Sharaf MA, Sweet F (September 1982). "Dual activity at an enzyme active site: 3 beta,20 alpha-hydroxysteroid oxidoreductase from fetal blood". Biochemistry. 21 (19): 4615–20. doi: 10.1021/bi00262a016. PMID 6958329.
