Ephedra (plant)

From Wikipedia, the free encyclopedia
  (Redirected from Mormon tea)

Ephedra
Temporal range: Aptian–Recent
Green ephedra Ephedra viridis close.jpg
Ephedra viridis
Scientific classification e
Kingdom: Plantae
Clade: Tracheophytes
Division: Gnetophyta
Class: Gnetopsida
Order: Ephedrales
Dumort. [2]
Family: Ephedraceae
Dumort. [1]
Genus: Ephedra
L. [1]
Map showing the range of Ephedra
Global range of Ephedra
Synonyms [3]

Alloephedra Tao JR et Yang Y., 2003. Chaetocladus Nelson 1866 nom. illeg. Liaoxia Cao et S.Q. Wu, 1996

Ephedra is a genus of gymnosperm shrubs. The various species of Ephedra are widespread in many arid regions of the world, ranging across southwestern North America, southern Europe, northern Africa, southwest and central Asia, northern China and western South America. [3] It is the only extant genus in its family, Ephedraceae, and order, Ephedrales and one of the three living members of the division Gnetophyta alongside Gnetum and Welwitschia.

In temperate climates, most Ephedra species grow on shores or in sandy soils with direct sun exposure. Common names in English include joint-pine, jointfir, Mormon-tea or Brigham tea. The Chinese name for Ephedra species is mahuang ( simplified Chinese: 麻黄; traditional Chinese: 麻黃; pinyin: máhuáng; Wade–Giles: ma-huang; lit. 'hemp yellow'). Ephedra is the origin of the name of the stimulant ephedrine, which the plants contain in significant concentrations.

Ephedra fragilis pollen cones
Ephedra distachya: ripe female cones with seeds

Description

The family Ephedraceae, of which Ephedra is the only genus, are gymnosperms, and generally shrubs, sometimes clambering vines, and rarely, small trees. Members of the genus frequently spread by the use of rhizomes. [4]

The stems are green and photosynthetic. [5] The leaves are opposite or whorled. The scalelike leaves fuse into a sheath at the base and this often sheds soon after development. There are no resin canals. [4]

The plants are mostly dioecious: with the pollen strobili in whorls of 1-10, each consisting of a series of decussate [6] bracts. The pollen is furrowed. The female strobili also occur in whorls, with bracts which fuse around a single ovule. There are generally 1-2 yellow to dark brown seeds per strobilus. [4]

Taxonomy

The genus Ephedra was first described in 1753 by Carl Linnaeus, [7] [8] [9] and the type species is Ephedra distachya. [8] The family, Ephedraceae, was first described in 1829 by Dumortier. [7] [10]

Evolutionary history

The oldest known members of the genus are from the Early Cretaceous around 125 million years ago, with records being known from the Aptian- Albian of Argentina, [11]China, [12] Portugal and the United States. [13] The fossil record of Ephedra outside of pollen disappears after the Early Cretaceous. [14] Molecular clock estimates have suggested that last common ancestor of living Ephedra species lived much more recently, during the Early Oligocene around 30 million years ago. [15] However, pollen modified from the ancestral condition of the genus with branched pseudosulci (grooves), which evolved in parallel in the living North American and Asian lineages is known from the Late Cretaceous, suggesting that the last common ancestor is at least this old. [14]

Species

As of June 2021, Plants of the World Online accepted the following species: [16]

Distribution

The genus is found worldwide, in desert regions, but not in Australia. [4]

Ecology

Shrubs of Ephedra major in Karvachar

Ephedraceae are adapted to extremely arid regions, growing often in high sunny habitats, and occur as high as 4000 m above sea level in both the Andes and the Himalayas. [4]

Drug and supplement uses

Plant as used in Chinese herbology ( crude medicine)

The Ephedra alkaloids, ephedrine and pseudoephedrine – constituents of E. sinica and other members of the genus – have sympathomimetic and decongestant qualities, [18] and have been used as dietary supplements, mainly for weight loss. [19] The drug, ephedrine, is used to prevent low blood pressure during spinal anesthesia. [18]

In the United States, ephedra supplements were banned from the market in the early 21st century due to serious safety risks. [19] Plants of the genus Ephedra, including E. sinica and others, were used in traditional medicine for treating headache and respiratory infections, but there is no scientific evidence they are effective or safe for these purposes. [19]

Adverse effects

Alkaloids obtained from the species of Ephedra used in herbal medicines, which are used to synthetically prepare pseudoephedrine and ephedrine, can cause cardiovascular events. [18] These events have been associated with arrhythmias, palpitations, tachycardia and myocardial infarction. [18] Caffeine consumption in combination with ephedrine has been reported to increase the risk of these cardiovascular events. [18] [19]

Economic botany and alkaloid content

Earliest uses of Ephedra spp. (mahuang) for specific illnesses date back to 5000 BC. Ephedrine and isomers were already isolated in 1881 from Ephedra dystachia and characterized by the Japanese organic chemist Nagai Nagayoshi of the 19th century. His work to access Ephedra drug materials to isolate a pure pharmaceutical substance, and the systematic production of semi-synthetic derivatives thereof is relevant still today as the three species Ephedra sinica, Ephedra vulgaris and to a lesser extent Ephedra equisetina are commercially grown in Mainland China as a source for natural ephedrines and isomers for use in pharmacy. E. sinica and E. vulgaris usually carry six optically active phenylethylamines, mostly ephedrine and pseudoephedrine with minor amounts of norephedrine, norpseudoephedrine as well as the three methylated analogs. Reliable information on the total alkaloid content of the crude drug is difficult to obtain. Based on HPLC analyses in industrial settings, the concentrations of total alkaloids in dried Herba Ephedra ranged between 1 and 4%, and in some cases up to 6%. [20]

For a review of the alkaloid distribution in different species of the genus Ephedra see Jian-fang Cui (1991). [21] Other American and European species of Ephedra, e.g. Ephedra nevadensis (Nevada Mormon tea) have not been systematically assayed; based on unpublished field investigations, they contain very low levels (less than 0.1%) or none at all. [22]

References

  1. ^ a b Kramer KU, Green PS, Götz E (1990). Kramer KU, Green PS (eds.). The Families and Genera of Vascular Plants, Vol. 1: Pteridophytes and Gymnosperms. Berlin: Springer-Verlag. pp. 379–381. ISBN  3540517944.
  2. ^ "Ephedrales Dumort". EU-NOMEN. Retrieved 20 January 2016.
  3. ^ a b Kew World Checklist of Selected Plant Families
  4. ^ a b c d e Judd WS, Campbell CS, Kellog EA, Stevens PF, Donoghue MJ (2007). Plant Systematics, a phylogenetic approach (3rd. ed.). Sinauer associates, Inc.
  5. ^ "Family "Ephedraceae"". Angiosperm Phylogeny Website. Retrieved 5 July 2019.
  6. ^ Messina A (2014). "VicFlora: Ephedraceae". Victoria, Australia: Royal Botanic Gardens Foundation. Retrieved 5 July 2019.
  7. ^ a b The Gymnosperm database: Ephedra. Retrieved 5 July 2019.
  8. ^ a b Linnaeus C (1753). Species Plantarum. 2. p. 1040.
  9. ^ Linnaeus C (1754). "Genera plantarum". p. 462.
  10. ^ Dumortier BC (1829). Analyse des familles des plantes, avec l'indication des principaux genres qui s'y rattachent. Tournay: J. Casterman aîné. p. 11.
  11. ^ Puebla GG, Iglesias A, Gómez MA, Prámparo MB (November 2017). "Fossil record of Ephedra in the Lower Cretaceous (Aptian), Argentina". Journal of Plant Research. 130 (6): 975–988. doi: 10.1007/s10265-017-0953-1. PMID  28528483. S2CID  23766815.
  12. ^ Yang Y, Wang Q (2013-01-14). "The earliest fleshy cone of Ephedra from the early cretaceous Yixian Formation of northeast China". PLOS ONE. 8 (1): e53652. Bibcode: 2013PLoSO...853652Y. doi: 10.1371/journal.pone.0053652. PMC  3544918. PMID  23341964.
  13. ^ Rydin C, Pedersen KR, Crane PR, Friis EM (July 2006). "Former diversity of Ephedra (Gnetales): evidence from Early Cretaceous seeds from Portugal and North America". Annals of Botany. 98 (1): 123–40. doi: 10.1093/aob/mcl078. PMC  2803531. PMID  16675607.
  14. ^ a b Bolinder, Kristina; Norbäck Ivarsson, Lena; Humphreys, Aelys M.; Ickert-Bond, Stefanie M.; Han, Fang; Hoorn, Carina; Rydin, Catarina (2016-01-02). "Pollen morphology of Ephedra (Gnetales) and its evolutionary implications". Grana. 55 (1): 24–51. doi: 10.1080/00173134.2015.1066424. ISSN  0017-3134. S2CID  83696018.
  15. ^ Ickert‐Bond, Stefanie M.; Rydin, Catarina; Renner, Susanne S. (2009). "A fossil-calibrated relaxed clock for Ephedra indicates an Oligocene age for the divergence of Asian and New World clades and Miocene dispersal into South America". Journal of Systematics and Evolution. 47 (5): 444–456. doi: 10.1111/j.1759-6831.2009.00053.x. ISSN  1759-6831.
  16. ^ "Ephedra Tourn. ex L." Plants of the World Online. Royal Botanic Gardens, Kew. Retrieved 2021-06-23.
  17. ^ Sharma P, Singh R (December 2016). "Ephedra yangthangensis (Ephedraceae), a new species from Himachal Pradesh, India. Bangladesh". Journal of Plant Taxonomy. 23 (2): 195–8. doi: 10.3329/bjpt.v23i2.30850.
  18. ^ a b c d e "Ephedrine". Drugs.com. 9 January 2021. Retrieved 23 June 2021.
  19. ^ a b c d "Ephedra". National Center for Complementary and Integrative Health, US National Institutes of Health. 1 July 2020. Retrieved 23 June 2021.
  20. ^ Brossi A, ed. (1989). The Alkaloids: Chemistry and Pharmacology. 35. ISBN  0-12-469535-3.
  21. ^ Kim HK, Choi YH, Erkelens C, Lefeber AW, Verpoorte R (January 2005). "Metabolic fingerprinting of Ephedra species using 1H-NMR spectroscopy and principal component analysis". Chemical & Pharmaceutical Bulletin. 53 (1): 105–9. doi: 10.1002/pca.2800020305. PMID  15635242.
  22. ^ Hegnauer R. (1962) "Chemotaxonomie der Pflanzen. I". Birkhauser Verlag, Basel; Switzerland, pp. 460–462 as cited in Roman MC (2004). "Determination of ephedrine alkaloids in botanicals and dietary supplements by HPLC-UV: collaborative study". Journal of AOAC International. 87 (1): 1–14. doi: 10.1093/jaoac/87.1.1. PMC  2584348. PMID  15084081.

External links