Clinical data | |
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Trade names | Viru-Merz |
AHFS/ Drugs.com | International Drug Names |
Routes of administration | Topical ( gel) |
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CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.053.409 |
Chemical and physical data | |
Formula | C16H28N2O2 |
Molar mass | 280.412 g·mol−1 |
3D model ( JSmol) | |
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(what is this?) (verify) |
Tromantadine is an antiviral medicine used to treat herpes simplex virus. It is available in a topical gel under trade names Viru-Merz and Viru-Merz Serol. Its performance is similar to aciclovir. [1] [2]
Like rimantadine, amantadine, and adapromine, tromantadine is a derivative of adamantane.
Tromantadine inhibits the early and late events in the virus replication cycle. [3] It changes the glycoproteins of the host cells, therefore impeding the absorption of the virus. It inhibits penetration of the virus. It also prevents uncoating of the virions.[ citation needed]