Low-density lipoprotein receptor-related protein 1B is a
protein that in humans is encoded by the LRP1Bgene.[5][6]
Function
LRP1B belongs to the
LDL receptor gene family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands.[7]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Liu CX, Musco S, Lisitsina NM, Forgacs E, Minna JD, Lisitsyn NA (May 2000). "LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines". Cancer Res. 60 (7): 1961–7.
PMID10766186.
Sonoda I, Imoto I, Inoue J, et al. (2004). "Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma". Cancer Res. 64 (11): 3741–7.
doi:
10.1158/0008-5472.CAN-04-0172.
PMID15172977.
S2CID12527714.
Li Y, Lu W, Bu G (2005). "Striking differences of LDL receptor-related protein 1B expression in mouse and human". Biochem. Biophys. Res. Commun. 333 (3): 868–73.
doi:
10.1016/j.bbrc.2005.05.170.
PMID15963947.