From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Guanylate cyclase soluble subunit alpha-2 is an
enzyme that in humans is encoded by the GUCY1A2
gene .
[5]
[6]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000152402 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000041624 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Harteneck C, Wedel B, Koesling D, Malkewitz J, Bohme E, Schultz G (Jan 1992).
"Molecular cloning and expression of a new alpha-subunit of soluble guanylyl cyclase. Interchangeability of the alpha-subunits of the enzyme" . FEBS Lett . 292 (1–2): 217–22.
doi :
10.1016/0014-5793(91)80871-Y .
PMID
1683630 .
S2CID
84974514 .
^
"Entrez Gene: GUCY1A2 guanylate cyclase 1, soluble, alpha 2" .
Further reading
Baba H, Suzuki T, Arai H, Emson PC (2004). "Expression of nNOS and soluble guanylate cyclase in schizophrenic brain". NeuroReport . 15 (4): 677–80.
doi :
10.1097/00001756-200403220-00020 .
PMID
15094474 .
S2CID
45536193 .
Bellamy TC, Wood J, Garthwaite J (2002).
"On the activation of soluble guanylyl cyclase by nitric oxide" . Proc. Natl. Acad. Sci. U.S.A . 99 (1): 507–10.
Bibcode :
2002PNAS...99..507B .
doi :
10.1073/pnas.012368499 .
PMC
117590 .
PMID
11752394 .
Russwurm M, Wittau N, Koesling D (2002).
"Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes" . J. Biol. Chem . 276 (48): 44647–52.
doi :
10.1074/jbc.M105587200 .
PMID
11572861 .
Bamberger AM, Koglin M, Kempfert J, et al. (2001).
"Expression and tissue localization of soluble guanylyl cyclase in the human placenta using novel antibodies directed against the alpha(2) subunit" . J. Clin. Endocrinol. Metab . 86 (2): 909–12.
doi :
10.1210/jcem.86.2.7409 .
PMID
11158065 .
Budworth J, Meillerais S, Charles I, Powell K (1999). "Tissue distribution of the human soluble guanylate cyclases". Biochem. Biophys. Res. Commun . 263 (3): 696–701.
doi :
10.1006/bbrc.1999.1444 .
PMID
10512742 .
Yu F, Warburton D, Wellington S, Danziger RS (1997).
"Assignment of GUCIA2, the gene coding for the alpha 2 subunit of soluble guanylyl cyclase, to position 11q21-q22 on human chromosome 11" . Genomics . 33 (2): 334–6.
doi :
10.1006/geno.1996.0208 .
PMID
8660992 .
Behrends S, Harteneck C, Schultz G, Koesling D (1995).
"A variant of the alpha 2 subunit of soluble guanylyl cyclase contains an insert homologous to a region within adenylyl cyclases and functions as a dominant negative protein" . J. Biol. Chem . 270 (36): 21109–13.
doi :
10.1074/jbc.270.36.21109 .
PMID
7673142 .
Activity Regulation Classification Kinetics Types