Edvard Ingjald Moser (pronounced[ˈɛ̀dvɑɖˈmoːsər];[surname tone?] born 27 April 1962) is a Norwegian psychologist and neuroscientist, who is a professor at the
Norwegian University of Science and Technology (NTNU) in
Trondheim.[1] In 2005, he and his then-wife
May-Britt Moser discovered
grid cells[2] in the brain's medial
entorhinal cortex. Grid cells are specialized neurons that provide the brain with a coordinate system and a metric for space. In 2018, he discovered a neural network that expresses a person's sense of time in experiences and memories located in the brain's lateral
entorhinal cortex.[3]
He shared the
Nobel Prize in Physiology or Medicine in 2014 with long-term collaborator and then-wife
May-Britt Moser, and previous mentor
John O'Keefe for their work identifying the brain's positioning system. The two main components of the brain's GPS are; grid cells and
place cells,[4] a specialized type of neuron that respond to specific locations in space.[5][6] Together with May-Britt Moser he established the
Moser research environment, which they lead.
Moser was born in
Ålesund to German parents Eduard Paul Moser (1928–2013) and Ingeborg Annamarie Herholz (1931–). His parents had grown up in
Kronberg im Taunus, a suburb of
Frankfurt, where Moser's grandfather Eduard Moser had been Lutheran parish priest. Moser's father trained as a
pipe organ builder and emigrated to Norway together with his friend Jakob Pieroth in 1953 when they were offered employment at a pipe organ workshop at
Haramsøy. They later established their own workshop and built many church pipe organs in Norway.[8][9] The Moser family originally was from
Nassau; Moser is a South German topographic name for someone who lived near a
swamp or
mire (South German Moos).[10] Edvard Moser grew up at
Hareid and in
Ålesund.[11][12][13] He was raised in a conservative
Christian family.[14]
Edvard Moser married
May-Britt Moser in 1985 when they were both students.[15] They announced that they are divorcing in 2016.[16]
Edvard Moser was awarded the cand.psychol. degree in psychology at the
Department of Psychology at the
University of Oslo in 1990. He was then employed as a research fellow at the Faculty of Medicine, where he obtained his dr.philos. doctoral research degree in the field of
neurophysiology in 1995.[18] He also has studied mathematics and statistics.[19] Early in his career, he worked under the supervision of
Per Andersen.
Moser returned to Norway in 1996 to be appointed associate professor in biological psychology at the Department of Psychology at the Norwegian University of Science and Technology (NTNU) in Trondheim. He was promoted to full professor of neuroscience in 1998. Moser is also head of department of the NTNU Institute for Systems Neuroscience.
Edvard Moser has been a member of the board of reviewing editors in science since 2004 and he has been reviewing editor for Journal of Neuroscience since 2005. Edvard Moser chaired the programme committee of the European Neuroscience meeting (
FENS Forum) in 2006.
Moser, E.I., Mathiesen, I. & Andersen, P. (1993). Association between brain temperature and dentate field potentials in exploring and swimming rats.
Science, 259, 1324–1326.
Brun, V.H., Otnæss, M.K., Molden, S., Steffenach, H.-A., Witter, M.P., Moser, M.-B., Moser, E.I. (2002). Place cells and place representation maintained by direct entorhinal-hippocampal circuitry.
Science, 296, 2089–2284.
Fyhn, M., Molden, S., Witter, M.P., Moser, E.I. and Moser, M.-B. (2004). Spatial representation in the entorhinal cortex.
Science, 305, 1258–1264Archived 17 February 2012 at the
Wayback Machine.
Leutgeb, S., Leutgeb, J.K., Treves, A., Moser, M.-B. and Moser, E.I. (2004). Distinct ensemble codes in hippocampal areas CA3 and CA1.
Science, 305, 1295–1298.
Leutgeb, S., Leutgeb, J.K., Barnes, C.A., Moser, E.I., McNaughton, B.L., and Moser, M.-B (2005). Independent codes for spatial and episodic memory in the hippocampus.
Science, 309, 619–623Archived 17 February 2012 at the
Wayback Machine.
Hafting, T., Fyhn, M., Molden, S., Moser, M.-B., and Moser, E.I. (2005). Microstructure of a spatial map in the entorhinal cortex.
Nature, 436, 801–806.
Colgin, L.L, and Moser, E.I. (2006). Rewinding the memory record.
Nature, 440, 615–617.
Sargolini, F., Fyhn, M., Hafting, T., McNaughton, B.L., Witter, M.P., Moser, M.-B., and Moser, E.I. (2006). Conjunctive representation of position, direction and velocity in entorhinal cortex.
Science, 312, 754–758.
Leutgeb, J.K., Leutgeb, S., Moser, M.-B., and Moser, E.I. (2007). Pattern separation in dentate gyrus and CA3 of the hippocampus.
Science, 315, 961–966.
Fyhn, M., Hafting, T., Treves, A., Moser, M.-B. and Moser, E.I. (2007). Hippocampal remapping and grid realignment in entorhinal cortex.
Nature, 446, 190–194.
Hafting, T., Fyhn, M., Bonnevie, T., Moser, M.-B. and Moser, E.I. (2008). Hippocampus-independent phase precession in entorhinal grid cells.
Nature 453, 1248–1252.
Kjelstrup, K.B., Solstad, T., Brun, V.H., Hafting, T., Leutgeb, S., Witter, M.P., Moser, E.I. and Moser, M.-B. (2008). Finite scales of spatial representation in the hippocampus.
Science 321, 140–143.
Solstad, T., Boccara, C.N., Kropff, E., Moser, M.-B. and Moser, E.I. (2008). Representation of geometric borders in the entorhinal cortex.
Science, 322, 1865–1868.
Moser, E.I., Moser, M-B. (2011). Crystals of the brain. EMBO Mol. Med. 3, 1–4.
Moser, E.I., Moser, M-B. (2011). Seeing into the future. Nature, 469, 303–4
Jezek, K., Henriksen, EJ., Treves, A., Moser, E.I. and Moser, M-B. (2011). Theta-paced flickering between place-cell maps in the hippocampus. Nature, 478, 246–249.
Giocomo, LM., Moser, E.I., Moser, M-B. (2011) Grid cells use HCN1 channels for spatial scaling. Cell, 147, 1159–1170.
Igarashi, KM., Lu L., Colgin LL., Moser M-B., Moser EI. (2014) Coordination of entorhinal-hippocampal ensemble activity during associative learning.
Nature 510, 143–7.
^Moser, M-B. (1995). Field potential changes in the dentate gyrus during spatial learning in the rat. Thesis for the degree of Dr. Philos., University of Oslo (defended on 9 December 1995).
^FENS Office (23 May 2013).
"Moser, Edvard I."FENS.org. Archived from
the original on 7 October 2014. Retrieved 7 October 2014.