From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Eukaryotic translation initiation factor 1A, Y-chromosomal is a
protein that in humans is encoded by the EIF1AY
gene .
[5]
[6]
Like its X-chromosomal counterpart
EIF1AX , it encodes an isoform of
eukaryotic translation initiation factor 1A (EIF1A). EIF1A is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the
5' end of capped
RNA . It has one amino acid difference (M50L) from EIF1AX.
[6]
References
Further reading
Lim J, Hao T, Shaw C, et al. (2006).
"A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration" . Cell . 125 (4): 801–14.
doi :
10.1016/j.cell.2006.03.032 .
PMID
16713569 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Fortna A, Kim Y, MacLaren E, et al. (2006).
"Lineage-Specific Gene Duplication and Loss in Human and Great Ape Evolution" . PLOS Biol . 2 (7): E207.
doi :
10.1371/journal.pbio.0020207 .
PMC
449870 .
PMID
15252450 .
Agate RJ, Choe M, Arnold AP (2004).
"Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches" . Mol. Biol. Evol . 21 (2): 384–96.
doi :
10.1093/molbev/msh027 .
PMID
14660691 .
Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, et al. (2003).
"The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes" . Nature . 423 (6942): 825–37.
Bibcode :
2003Natur.423..825S .
doi :
10.1038/nature01722 .
PMID
12815422 .
Marintchev A, Kolupaeva VG, Pestova TV, Wagner G (2003).
"Mapping the binding interface between human eukaryotic initiation factors 1A and 5B: A new interaction between old partners" . Proc. Natl. Acad. Sci. U.S.A . 100 (4): 1535–40.
Bibcode :
2003PNAS..100.1535M .
doi :
10.1073/pnas.0437845100 .
PMC
149867 .
PMID
12569173 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .