From Wikipedia, the free encyclopedia
Christopher Boyce Burge is Professor of Biology and Biological Engineering at
Massachusetts Institute of Technology .
Education
Burge completed his
Bachelor of Science at
Stanford University in 1990, and continued graduate studies in
computational biology at Stanford University, gaining his
PhD
[7] in 1997
[4] under the supervision of
Samuel Karlin .
[5]
[6] During his time at Stanford he was responsible for developing algorithms for
GENSCAN used in
gene prediction for example the initial analysis of the
Human Genome Project .
[8] His PhD thesis was titled Identification of genes in human genomic DNA .
Research
From 1997 to 1999 Burge worked as a
postdoc in the laboratory of
Phillip Allen Sharp , working in the fields of
RNA splicing and
molecular evolution .
[9] Burge joined the Massachusetts Institute of Technology in 1999 as a
Bioinformatics Fellow. He became Assistant Professor in 2002, Associate Professor in 2004, was tenured in 2006, and was promoted to full Professor in 2010. He has been an Associate Member of the
Broad Institute since 2004.
[4] His current research interests include
genomics , RNA splicing and
microRNA
[10] regulation.
[11]
[12]
[13]
[14]
Burge has also served on the editorial boards of the academic journals
RNA ,
PLOS Computational Biology ,
BMC Bioinformatics and
BMC Genomics .
[4]
Awards
In 2001 he was awarded the
Overton Prize
[1] for Computational Biology by the
International Society for Computational Biology . He was awarded a
Searle Scholar Award in 2003 for his research in the computational biology of
gene expression .
[2] In 2007 he was awarded the Schering-Plough Research Institute Award (now known as the ASBMB Young Investigator Award) by the
American Society for Biochemistry and Molecular Biology for his outstanding research contributions to biochemistry and molecular biology.
[15]
References
^
a
b
"Overton Prize" . www.iscb.org . Retrieved 23 May 2021 .
^
a
b
"Searle Scholars Program: Christopher Burge (2003)" . Archived from
the original on 5 September 2015. Retrieved 10 August 2015 .
^
Christopher Burge at the
Mathematics Genealogy Project
^
a
b
c
d
http://genes.mit.edu/burgelab/CBurgeCV.pdf
Archived 2011-08-17 at the
Wayback Machine Christopher Burge CV
^
a
b
Burge, Christopher ;
Karlin, Samuel (1997).
"Prediction of complete gene structures in human genomic DNA" (PDF) . Journal of Molecular Biology . 268 (1): 78–94.
doi :
10.1006/jmbi.1997.0951 .
PMID
9149143 . Archived from
the original (PDF) on 2015-06-20.
^
a
b
Burge, C. ;
Karlin, S. (1998).
"Finding the genes in genomic DNA" . Current Opinion in Structural Biology . 8 (3): 346–354.
doi :
10.1016/S0959-440X(98)80069-9 .
PMID
9666331 .
^
Burge, Christopher Boyce (2012). Identification of genes in human genomic DNA (PhD thesis). Stanford University.
ProQuest
304386368 .
^
Lander, E. S. ; Linton, M.; Birren, B.; Nusbaum, C.; Zody, C.; Baldwin, J.; Devon, K.; Dewar, K.; Doyle, M.; Fitzhugh, W.; Funke, R.; Gage, D.; Harris, K.; Heaford, A.; Howland, J.; Kann, L.; Lehoczky, J.; Levine, R.; McEwan, P.; McKernan, K.; Meldrim, J.; Mesirov, J. P.; Miranda, C.; Morris, W.; Naylor, J.; Raymond, C.; Rosetti, M.; Santos, R.; Sheridan, A.; et al. (Feb 2001).
"Initial sequencing and analysis of the human genome" (PDF) . Nature . 409 (6822): 860–921.
Bibcode :
2001Natur.409..860L .
doi :
10.1038/35057062 .
ISSN
0028-0836 .
PMID
11237011 .
^ Burge, C.; Padgett, R.; Sharp, P. (1998).
"Evolutionary fates and origins of U12-type introns" . Molecular Cell . 2 (6): 773–785.
doi :
10.1016/S1097-2765(00)80292-0 .
PMID
9885565 .
^ Rhoades, M. W.; Reinhart, B. J.; Lim, L. P.; Burge, C. B.; Bartel, B.; Bartel, D. P. (2002).
"Prediction of Plant MicroRNA Targets" . Cell . 110 (4): 513–520.
doi :
10.1016/S0092-8674(02)00863-2 .
PMID
12202040 .
^
Christopher Burge's publications indexed by the
Scopus bibliographic database. (subscription required)
^
http://www.biomedexperts.com/Profile.bme/172484/Christopher_B_Burge
Archived 2012-03-21 at the
Wayback Machine Chris Burge profile in
BiomedExperts
^ Lewis, B. P.; Burge, C. B.; Bartel, D. P. (2005).
"Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets" . Cell . 120 (1): 15–20.
doi :
10.1016/j.cell.2004.12.035 .
PMID
15652477 .
^ Lewis, B. P.; Shih, I. H.; Jones-Rhoades, M. W.; Bartel, D. P.; Burge, C. B. (2003).
"Prediction of Mammalian MicroRNA Targets" . Cell . 115 (7): 787–98.
doi :
10.1016/S0092-8674(03)01018-3 .
PMID
14697198 .
^
"ASBMB Young Investigator Award formerly the ASBMB Schering-Plough Research Institute Award" . Retrieved 10 August 2015 .