U.S. Route 501
US 501 highlighted in red
|Auxiliary route of US 1|
|Length||355 mi    (571 km)|
US 17 Bus. in Myrtle Beach, SC
|North end||US 60 in Buena Vista, VA|
|States||South Carolina, North Carolina, Virginia|
NC: Robeson, Scotland, Hoke, Moore, Lee, Chatham, Orange, Durham, Person
VA: Halifax, Campbell, City of Lynchburg, Bedford, Amherst, Rockbridge, City of Buena Vista
U.S. Route 501 (US 501) is a spur of U.S. Route 1. It runs 355 miles (571 km) from Buena Vista, Virginia at U.S. Route 60 to Myrtle Beach, South Carolina at U.S. Route 17 Business. It passes through the states of Virginia, North Carolina and South Carolina. From Durham to Laurinburg, a 108-mile (174 km) section of US 501 overlaps U.S. Route 15. Sections of US 15-501 also share routings with U.S. Route 1 in sections near Sanford, North Carolina and Aberdeen, North Carolina.
US 501 in South Carolina is a north–south United States highway that traverses 73.8 miles (118.8 km); it is one of main routes to the Grand Strand. US 501 begins at US 17 Bus. in Myrtle Beach, South Carolina. From Myrtle Beach to Marion, US 501 is a multilane highway, some sections divided, some undivided, mostly with at-grade intersections but having a number of interchanges along the length. The first of these interchanges is with US 17, which is a cloverleaf interchanges that includes railroad crossings at the ramps along the east side. After the bridge over the Intracoastal Waterway it has two more interchanges with local roads. Next there is an unusual hybrid interchange with South Carolina Highway 31, similar to a cloverstack, with elements of a trumpet interchange, in which two flyover ramps from SC 31 to US 501 exit left from SC 31 and wrap around the interchange's loop ramps. After this interchange, this limited-access portion comes to an end. US 501 passes through the city of Conway where it has a short overlap with U.S. Route 701. South of Aynor it serves as the western terminus of SC 22, which has another unconventional interchange, and various interchanges can also be found along the road before reaching Marion, where US 501 bypasses the town to the east. North of Marion, US 501 meets SC 38, a connector to Interstate 95. From SC 38, US 501 heads to the northeast, meeting US 301 in Latta. US 301 merges with US 501, forming a concurrency through Dillon to the North Carolina border, where it passes South of the Border prior to simultaneously exiting South Carolina and interchanging with Interstate 95 near Hamer in Dillon County.
US 501 is a north–south United States highway that traverses the majority of North Carolina in concurrency with US 15, known as "15-501" ("Fifteen Five-o-one"). It enters North Carolina at the South Carolina state line with an intersection of Interstate 95 (I-95) while overlapping US 301, near South of the Border. It goes northwest through Rowland where the overlap with US 301 terminates, and then travels through Raemon to Laurinburg. Once at Laurinburg, it overlaps briefly with I-74/ US 74 before connecting with US 15. The majority of the route, to this point, is a two-lane rural road. 
Merging with US 15, it becomes what is known by local residents as "15-501" ("Fifteen Five-o-one"), a concurrency that extends for 106 miles (171 km) across central North Carolina. After Laurinburg it goes north to Aberdeen, linking briefly with US 1 before continuing to Pinehurst. In Pinehurst, 15-501 goes through a roundabout then continues north through Carthage, then back to US 1. After traveling through Sanford on another brief concurrency with US 1, it exits off the freeway and goes due north to Pittsboro. After Pittsboro, 15-501 goes through Chapel Hill and then into Durham. NCDOT has been trying to remedy traffic problems by making the route a superstreet for better traffic flow.  In Durham, 15-501 upgrades to an urban freeway, allowing for quick access to Interstate 85, and from south Durham to north; the freeway ends merging into I-85. At exit 176B on I-85, US 501 splits off towards Roxboro, while US 15 continues with I-85 towards Oxford. 
US 501 enters Halifax County, Virginia south of Cluster Springs. The U.S. Highway is a two-lane road at the North Carolina state line but immediately expands to a four-lane divided highway named Huell Matthews Highway. US 501 parallels the Mayo River north to the hamlet of Mayo, where the highway meets the western end of SR 96 (Virgilina Road) and crosses the Hyco River. The U.S. Highway passes through Cluster Springs to the community of Riverdale just south of South Boston. US 501 becomes an undivided highway and intersects US 58 and US 360, which together head west as Philpott Road and east as Bill Tuck Highway. US 501 crosses the Dan River into the town of South Boston. Just north of the river, the highway has a grade crossing of Norfolk Southern Railway's Clover Spur, which follows the former Danville– Richmond rail line, and splits into a one-way pair: Broad Street northbound and Main Street southbound. Both directions intersect SR 304 (Seymour Drive). When Main Street veers northeast as two-way SR 129, southbound US 501 continues on two-way Wilborn Avenue to the northern end of the one-way pair.  
US 501 continues through South Boston on Wilborn Avenue, a five-lane road with center turn lane. The U.S. Highway becomes four-lane divided Halifax Road at Hamilton Boulevard. US 501 receives the northern end of SR 129 (Old Halifax Road) shortly before leaving the town of South Boston. The U.S. Highway enters the town of Halifax and becomes Main Street, a three-lane road with center turn lane, at its grade crossing of Norfolk Southern's Durham District. US 501 continues to the county courthouse, where the highway intersects the very short SR 349 (Edmunds Boulevard) and SR 360 (Mountain Road), which runs concurrently with the U.S. Highway through the northern part of the town. The two highways diverge: SR 360 heads northeast as Bethel Road and US 501 heads northwest as two-lane L.P. Bailey Memorial Highway. which crosses Banister Lake, an impoundment of the Banister River, as it leaves the town of Halifax.  
US 501 passes through Volens and Acorn on its way to the hamlet of North Halifax, where the highway begins to run concurrently with SR 40 (Stage Coach Road). The highways cross the Roanoke River into the town of Brookneal in Campbell County and pass under Norfolk Southern's Altavista District rail line. The highways continue as Lusardi Drive to Lynchburg Avenue in the center of town; SR 40 turns southeast while US 501 turns north west onto the street just north of the highways' grade crossing of the Durham District rail line. US 501 leaves the town as Brookneal Highway, which parallels the rail line through the communities of Naruna and Gladys on its way to Rustburg, the county seat of Campbell County. The U.S. Highway intersects SR 24 (Colonial Highway) at the southern edge of the village. The highways have a short concurrency before SR 24 continues east as Village Highway and US 501 heads northwest as Campbell Highway. North of Rustburg, US 501 expands to a four-lane divided highway into the independent city of Lynchburg, where the highway meets US 29 and US 460 (Richmond Highway) at a partial cloverleaf interchange. US 501 Business and US 460 Business head straight on Campbell Avenue while US 501 joins the freeway heading southwest.  
US 501 runs concurrently with US 29 and US 460 southwest along the northern slope of Candlers Mountain to a full Y interchange where US 501 heads northwest from the freeway. The U.S. Highway has an intersection with SR 128 (Mayflower Drive) and Candlers Mountain Road just east of the highway's crossing of Norfolk Southern's Danville District. SR 128 joins US 501 on Candlers Mountain Road between the intersection and the highway's cloverleaf interchange with US 29 Business (Lynchburg Expressway). US 501 exits onto the expressway while SR 128 continues west to its terminus. US 501 and US 29 Business head southwest along the freeway until the business route exits onto Wards Road to head toward Danville. US 501 curves northwest and has a cloverleaf interchange with US 460 Business (Timberlake Road), crosses Norfolk Southern's Blue Ridge District, and has a diamond interchange with Graves Mill Road. The freeway ends at US 221 (Lakeside Drive). US 501 heads north along Old Forest Road as a five-lane road with center turn lane before turning onto a two-lane segment of the Lynchburg Expressway. This segment has a partial cloverleaf interchange with Wiggington Road before ending at US 501 Business (Boonsboro Road).  
US 501 heads northwest on two-lane Boonsboro Road, which becomes Lee Jackson Highway when it exits the city of Lynchburg into Bedford County. The U.S. Highway curvaceously crosses Fleming Mountain and descends into the James River Gorge at Coleman Falls. US 501 follows the south bank of the river through Big Island, where the highway meets the northern end of SR 122 (Big Island Highway) and has an interchange with the Blue Ridge Parkway. North of Big Island, the U.S. Highway crosses the river and immediately intersects SR 130 (Elon Road) on the Amherst County side. The two highways have a curvaceous crossing of the spine of the Blue Ridge Mountains before descending to the town of Glasgow at the mouth of the Maury River. The two routes follow the river upstream a short distance before SR 130 (Wert Faulkner Highway) crosses the river into the town. US 501, now named Glasgow Highway, parallels the river and Norfolk Southern's Roanoke District rail line north to the city of Buena Vista, which the highway enters as Magnolia Avenue. South of the downtown area, US 501 veers onto Sycamore Street while US 501 Business continues along Magnolia Avenue. At 22nd Street, the U.S. Highway veers onto Beech Avenue, which receives the northern end of US 501 Business (Park Avenue) west of Southern Virginia University. Two blocks to the north, US 501 reaches its northern terminus at US 60 (29th Street).  
Established in 1935 as in extension from North Carolina. US 501 replaced part of US 117 between Myrtle Beach to Socastee, then from there through Conway, Marion, and Latta on what was SC 38. North of Latta, it overlapped with US 301, through Dillon, and into North Carolina.
During the 1940s, because of the need for a more direct route to Myrtle Beach Air Force Base from Conway, 2-lane US 501 was built through the Buist Tract owned by Southern Kraft Company (later part of International Paper),  replacing SC 503, its old alignment was renumbered to SC 544. In 1950, US 501 was moved onto new construction between Conway and Aynor, its old alignment renumbered to SC 319. By 1964, US 501 was moved to its current southern bypass from downtown Conway, creating US 501 Bus. By 1990, US 501 was moved to its current eastern bypass from downtown Marion, creating another US 501 Bus.
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When US 501 was established in 1927, it was aligned along North Carolina Highway 13 (NC 13) from Durham north through Roxboro to the Virginia state line.
In 1934, it was overlapped with US 15 from Durham south to Laurinburg. From there, it went southeast to Rowland and then to the South Carolina border. This extension south replaced NC 22, NC 71, and NC 241.
In 1953, US 501 was bypassed around Chapel Hill. In 1956 or 1957, US 501 was bypassed west of Sanford. Between 1960-1962, US 501 was bypassed around Laurinburg. 
|Location||Durham– Virginia State Line|
|Length||43 mi  (69 km)|
North Carolina Highway 13 was an original state highway running from Durham, north through Rougemont and Roxboro ending at SR 18 at the Virginia State Line. The highway's routing appeared on the 1916 Highway Map by the North Carolina State Highway Commission for the five year federal aid program.  However NC 13 was not officially marked on any state highway maps until 1924; where it was routed from NC 10/NC 75 in Durham north through Rougemont and Timberlake to NC 57 east of Roxboro. NC 13 turned toward the west into Roxboro, before intersecting NC 144 and turning north.  The highway had its northern terminus at the Virginia State Line near South Boston. By 1926 the routing of NC 13 was shifted slightly to the west between Timberlake and Roxboro, providing a direct link between the cities.  The route was deleted in 1930, with US 501/NC 55 taking over the entirety of the routing.  
|State||County||Location||mi   ||km||Exit||Destinations||Notes|
|South Carolina||Horry||Myrtle Beach||0.0||0.0|
US 17 Bus. – North Myrtle Beach, Surfside Beach
|Southern terminus of US 501|
|1.3||2.1||Robert M. Grissom Parkway||To Myrtle Beach International Airport|
|2.1||3.4||US 17 – North Myrtle Beach, Georgetown||Cloverleaf interchange|
|Bridge over Intracoastal Waterway|
|||River Oaks Drive / George Bishop Parkway||Interchange|
|||Dick Scobee Drive / Forestbrook Road||Interchange|
|||5.1||8.2||SC 31 (Carolina Bays Parkway) to SC 9 – North Myrtle Beach, Georgetown||Hybrid interchange|
US 501 Bus. north to SC 90 / SC 905 – Conway
|11.3||18.2||SC 544 – Socastee, Surfside Beach, Garden City, Murrells Inlet|
|14.3||23.0||US 378 (Wright Boulevard) / US 701 south (Church Street) to SC 905 – Lake City, Georgetown||South end of US 701 overlap|
US 701 north / US 501 Bus. south (16th Avenue) – Loris
|North end of US 701 overlap; Begin US 701 Truck overlap|
US 701 Truck north (Mill Pond Road)
|North end of US 701 Truck overlap|
|||22.6||36.4||SC 22 east (Veterans Highway) – Myrtle Beach, North Myrtle Beach||Interchange; western terminus of SC 22|
|Aynor||29.2||47.0||SC 319 south (Elm Street)||Northern terminus of SC 319|
|Marion||Ariel Crossroad||37.2||59.9||SC 41 – Mullins, Johnsonville||Interchange|
US 501 Bus. north to US 76 west – Marion, Florence
|Marion||47.7||76.8||US 76 – Marion, Mullins||Interchange|
SC 41 Alt. – Marion, Lake View
US 501 Bus. south – Marion
|||56.6||91.1||SC 38 west to I-95 – Bennettsville||Interchange; southern terminus of SC 38|
|Dillon||||I-73||Proposed interchange  |
|Latta||59.8||96.2||US 301 south – Florence||South end of US 301 overlap|
|60.3||97.0||SC 917 south (Main Street) – Mullins, Bennettsville|
|Dillon||66.8||107.5||SC 9 south / SC 34 west / SC 57 south (Main Street) – Lake View, North Myrtle Beach||South end of SC 9/SC 57 overlap; Eastern terminus of SC 34|
|67.8||109.1||SC 9 north / SC 57 north (Radford Boulevard) – Bennettsville, Charlotte||North end of SC 9/SC 57 overlap|
|South Carolina–North Carolina state line|
|North Carolina||Robeson||||0.0||0.0||I-95 – Lumberton, Fayetteville, Florence||Exits 1A–1B (I-95)|
|Rowland||2.7||4.3||US 301 north / NC 130 east – Lumberton, Fairmont||North end of US 301 and east end of NC 130 overlap|
|||4.0||6.4||NC 710 west – Pembroke|
|Raemon||10.2||16.4||NC 130 west – Maxton||West end of NC 130 overlap|
|||14.0||22.5||NC 83 – Maxton, Clio|
US 501 Bus. north (Johns Road)
|21.7||34.9||I-74 east / US 74 east – Lumberton, Wilmington||East end of I-74/US 74 overlap|
|US 501 overlaps with Interstate 74 (exits 185 to 183).|
|Laurinburg||23.2||37.3||I-74 west / US 15 south / US 74 west / US 401 south – Hamlet, Rockingham, McColl||South end of US 15/US 401 overlap|
US 74 Bus. (Church Street) – Hamlet
US 401 north / US 15 Bus. south / US 501 Bus. south – Fayetteville
|North end of US 401 overlap|
|||29.3||47.2||NC 144 (Old Wire Road) – Wagram|
||No major junctions|
|Moore||Aberdeen||49.1||79.0||NC 211 east – Raeford||East end of NC 211 overlap|
|49.5||79.7||US 1 south – Rockingham||South end of US 1 overlap|
|49.7||80.0||NC 5 – Pinehurst|
|51.4||82.7||US 1 north – Southern Pines||North end of US 1 overlap|
|Pinehurst||55.2||88.8||NC 2 / NC 211 west – Southern Pines, West End||Roundabout, west end of NC 211 overlap|
|||59.0||95.0||NC 73 west – West End|
|Carthage||62.5||100.6||NC 22 south – Southern Pines||South end of NC 22 overlap|
|63.6||102.4||NC 22 north (McNiell Street)||North end of NC 22 overlap|
|65.7||105.7||NC 24 east / NC 27 east (Monroe Street)||East end of NC 24/NC 27 overlap|
|||67.5||108.6||NC 24 east / NC 27 east – Cameron||West end of NC 24/NC 27 overlap|
|Lee||||76.0||122.3||US 1 south – Cameron, Southern Pines||South end of US 1 overlap|
|Tramway||78.6||126.5||NC 78 east (Tramway Road) – Cameron|
US 1 Bus. north / NC 42 – Asheboro, Fuquay-Varina
|82.8||133.3||69A||US 421 / NC 87 south – Dunn, Greensboro||South end of NC 87 overlap|
|84.0||135.2||70||Oscar Keller Jr Highway – Fuquay-Varina||Future US 421|
US 1 north / US 1 Bus. south – Apex, Raleigh
|North end of US 1 overlap|
|Chatham||Pittsboro||98.2||158.0||NC 87 north – Graham, Burlington||North end of NC 87 overlap|
US 64 Bus.
|101.8||163.8||US 64 – Siler City, Apex|
|Orange||Chapel Hill||115.0||185.1||NC 54 west – Graham||South end of NC 54 overlap|
|117.2||188.6||NC 54 east (Raleigh Road)||North end of NC 54 overlap|
|Durham||Durham||121.0||194.7||I-40 – Greensboro, Raleigh|
US 15 Bus. north / US 501 Bus. north (Durham-Chapel Hill Boulevard)
|125.5||202.0||107||NC 751 (Cameron Boulevard)|
US 70 Bus. (Hillsborough Road) / NC 147 (Durham Freeway)
|Signed as exits 108A (NC 147 south), 108B (NC 147 north), 108C (Hillsbrough Road)|
|127.4||205.0||109||I-85 south – Greensboro||South end of I-85 overlap; southbound exit and northbound entrance|
|US 501 overlaps with Interstate 85 (exits 174A to 176B).|
|130.0||209.2||I-85 north / US 15 north / US 70 east – Henderson, Petersburg||North end of I-85/US 15 and east end of US 70 overlap|
US 501 Bus. (Roxboro Street)
|Person||||146.0||235.0||NC 57 south – Hillsborough||South end of NC 57 overlap|
|Roxboro||156.5||251.9||US 158 east – Oxford||East end of US 158 overlap|
|157.0||252.7||NC 157 south – Durham|
|158.0||254.3||US 158 west / NC 49 south / NC 57 north – Yanceyville, Milton, Haw River||West end of US 158, south end of NC 49, and north end of NC 57 overlap|
|159.0||255.9||NC 49 north (Virgilina Road) – Virgilina||North end of NC 49 overlap|
|North Carolina–Virginia state line|
|Virginia||Halifax||||2.46||3.96||SR 96 east (Virgilina Road) – Virgilina|
US 58 / US 360 / US 501 Truck north (Bill Tuck Highway) – Danville, Clarksville, Richmond, South Hill
|South Boston||11.56||18.60||SR 304 east (Seymour Drive)|
|11.78||18.96||SR 129 north (North Main Street)|
|Edmunds Street||Former SR 152|
US 501 Truck south (Hamilton Boulevard)
|14.62||23.53||SR 129 south (Old Halifax Road) / SR 884 west (Powell Road) – South Boston|
|Halifax||16.92||27.23||SR 360 west (Mountain Road)||South end of concurrency with SR 360|
|17.70||28.49||SR 360 east (Bethel Road) – Crystal Hill, Richmond||North end of concurrency with SR 360|
|Volens||SR 603 (Cody Road) – Republican Grove, Cody||Former SR 126 north|
|North Halifax||38.25||61.56||SR 40 west (Stage Coach Road) / SR 632 east (Hog Wallow Road) – Gretna||South end of concurrency with SR 40|
|Campbell||Brookneal||40.07||64.49||SR 40 east (Lynchburg Avenue) – Charlotte CH, Patrick Henry Boys Home||North end of concurrency with SR 40|
|Gladys||SR 652 (Pigeon Run Road) / SR 761 (Long Island Road) – Long Island, Altavista||Former SR 126 south|
|Rustburg||59.59||95.90||SR 24 west (Colonial Highway) to US 29 – Roanoke||South end of concurrency with SR 24|
|60.51||97.38||SR 24 east (Village Highway) – Concord||North end of concurrency with SR 24|
|City of Lynchburg||68.47||110.19|
US 29 north / US 460 east / US 460 Bus. west / US 501 Bus. north (Campbell Avenue) – Charlottesville, Appomattox, Washington
|South end of freeway section; south end of concurrency with US 29 and US 460|
|Odd Fellows Road|
|70.83||113.99||US 29 south / US 460 west – Roanoke, Danville||North end of freeway section; north end of concurrency with US 29 and US 460|
|71.42||114.94||SR 128 east (Mayflower Drive) / SR 670 south (Candlers Mountain Road) – Liberty University||South end of concurrency with SR 128; partial interchange with SR 670|
US 29 Bus. north ( Lynchburg Expressway east) / SR 128 west (Candlers Mountain Road) – Charlottesville
|North end of concurrency with SR 128; south end of concurrency with US 29 Bus.; south end of freeway section; Lynchburg Expwy. exit 8B|
US 29 Bus. south – Danville
|Exit numbers follow Lynchburg Expwy.; north end of concurrency with US 29 Bus.|
US 460 Bus. (Timberlake Road / Fort Avenue)
|Signed as exits 10A (east) and 10B (west)|
|74.88||120.51||11||Graves Mill Road||Former SR 126|
|—||To Breezewood Drive||Southbound exit and entrance only|
|76.12||122.50||US 221 (Lakeside Drive) – Thomas Jefferson's Poplar Forest, Lynchburg College||Intersection; north end of freeway section; west end of Lynchburg Expressway|
|Old Forest Road||Former SR 291 north|
|77.66||124.98||Wiggington Road – Peaks View Park||Interchange|
US 501 Bus. south (Boonsboro Road)
|Bedford||Big Island||91.28||146.90||SR 122 south (Big Island Highway) – Bedford|
|||Blue Ridge Parkway||Interchange|
|Amherst||||95.75||154.09||SR 130 east (Elon Road) – Lynchburg||South end of concurrency with SR 130|
|Rockbridge||||102.12||164.35||SR 130 west (Wert Faulkner Highway) – Glasgow, Natural Bridge||North end of concurrency with SR 130|
|City of Buena Vista||110.52||177.86|
US 501 Bus. north (Magnolia Avenue)
US 501 Bus. south (Park Avenue)
|111.42||179.31||US 60 (29th Street) to I-81||Northern terminus of US 501|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|
- Google (June 30, 2013). "U.S. Route 501 in South Carolina" (Map). Google Maps. Google. Retrieved June 30, 2013.
- Google (February 1, 2011). "US 501 in NC" (Map). Google Maps. Google. Retrieved February 1, 2011.
- "2009 Traffic Data". Virginia Department of Transportation. 2009. Retrieved 2011-10-04.
- "NCDOT: Super Street" (PDF). Archived from the original (PDF) on May 28, 2010. Retrieved February 1, 2011.
- Google (2011-10-04). "U.S. Route 501 in Virginia" (Map). Google Maps. Google. Retrieved 2011-10-04.
- Straka, Thomas J.; Dantzler, David W.; Yarrow, Greg K.; Burroughs, J. Benjamin (2006). "History of the 'Infamous Buist Tract' and Its Wildfires". The Independent Republic Quarterly. Horry County Historical Society. pp. 7–8. Retrieved April 12, 2016.
- "NCRoads.com: U.S. 15 and 501". Retrieved August 19, 2012.[ self-published source]
- North Carolina State Highway Commission (1929). State Highway System of North Carolina (Map). Bynum Publishing Company. Retrieved August 1, 2016.
- North Carolina State Highway Commission (1916). Highway Map of North Carolina (Map). North Carolina State Highway Commission. Retrieved August 1, 2016.
- North Carolina State Highway Commission (1924). State Highway System of North Carolina (Map). North Carolina State Highway Commission. Retrieved August 1, 2016.
- North Carolina State Highway Commission (1926). State Highway System of North Carolina (Map). North Carolina State Highway Commission. Retrieved August 1, 2016.
- North Carolina State Highway Commission (1930). State Highway System of North Carolina (Map). Bynum Publishing Company. Retrieved August 1, 2016.
- Staff. "Project Status: Southern Project". I-73 Environmental Impact Study. South Carolina Department of Transportation. Retrieved June 30, 2013.
- I-73 Southern Map (PDF) (Map). South Carolina Department of Transportation. Marion inset. Retrieved June 30, 2013.
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