South and east of Naples, US 41 turns eastward as
SR 90 as the Tamiami Trail crosses the
Everglades on its way to
Miami; north of High Springs, US 41 overlaps US 441 (SR 25) until their split in
Lake City (from there US 41 continues to the
Georgia border with the hidden SR 25 designation).
Separations of US 41 and SR 45 between SR 45 termini
SR 45 in South Seminole Heights, Tampa, south of SR 574. Taken on April 8, 2006.
State Road 45A (SR 45A) is the Venice Bypass, a segment along
U.S. Route 41 (US 41) east of the
Tamiami Trail in
Venice, which was originally part of US 41 until 1965 when that segment was redesignated as
US 41 Bus after the
Intracoastal Waterway (ICW) was dredged through Venice by the
U.S. Army Corps of Engineers in 1964.[2] The route begins near Shamrock Boulevard in
Venice Gardens and terminates at Venetia Bay Boulevard in the Eastgate section of Venice.