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Not to be confused with Rosemary Carpenter Fitzgerald.

Rosemary Carpenter
Alma materUniversity of East Anglia
Scientific career
InstitutionsJohn Innes Centre
Thesis Studies on genetic instability in Antirrhinum majus (1998)

Rosemary Carpenter is a British plant geneticist known for her work on members of the genus Antirrhinum, commonly known as a snapdragon, for which she and Enrico Coen were awarded the 2004 Darwin Medal by the Royal Society. [1]

Career

Starting in the 1960, Carpenter worked with Brian Harrison at the John Innes Centre on unstable mutants of the snapdragon Antirrhinum. [2] After meeting Carpenter during an interview at the John Innes Centre in 1983, Enrico Coen joined the center and they began a long collaboration with him using snapdragons as a model system to understand jumping genes and evolution. [3] [2] They applied a combination of molecular, genetic and morphological approaches to snapdragons with the goal of elucidating patterns in flower development [4] using the hundreds of Antirrhihum mutants established by Carpenter. [5] Carpenter retired in 2003. [6]

Carpenter is a plant geneticist who worked on Antirrhinum, snapdragons.

Research

Carpenter is a plant geneticist known for her research on the population genetics of the snapdragon, Antirrhihum. [7] [2] Working with Brian Harrison in the 1970s, she defined genetic instabilities in Antirrhinum and the role of temperature in controlling the rate of instability of specific genes [8] [9] and transposable elements that occur in both maize and snapdragons. [10] This was the first time a link between genetic instability and Antirrhihum was formalized, a milestone in research using snapdragons. [11] The instability of genes in snapdragons begin Carpenter's collaboration with Enrico Coen, where they first worked on transposons and the effect of temperature on the excision of specific genes [12] and how the transposable elements cause variability in gene expression. [13] [14] Carpenter, Coen, and their students isolated the genes controlling floral development. [15] [16] [17] These genetic investigations allowed them to define the patterns of color, [18] [19] shape, [20] [21] [22] and floral asymmetry [23] [24] in snapdragons and other plants. Carpenter's research on snapdragons includes investigations of how snapdragons select their colors using small RNA, [25] which alter the selection of colors in the snapdragons. [26]

Selected publications

  • Carpenter, R; Coen, E S (1 September 1990). "Floral homeotic mutations produced by transposon-mutagenesis in Antirrhinum majus". Genes & Development. 4 (9): 1483–1493. doi: 10.1101/gad.4.9.1483. ISSN  0890-9369. PMID  1979295.
  • Coen, Enrico S.; Romero, JoséM.; Doyle, Sandra; Elliott, Robert; Murphy, George; Carpenter, Rosemary (1990). "floricaula: A homeotic gene required for flower development in antirrhinum majus". Cell. 63 (6): 1311–1322. doi: 10.1016/0092-8674(90)90426-F. PMID  1702033. S2CID  46586130.
  • Carpenter, R.; Coen, E.S. (1 January 1995). "Transposon induced chimeras show that floricaula, a meristem identity gene, acts non-autonomously between cell layers". Development. 121 (1): 19–26. doi: 10.1242/dev.121.1.19. ISSN  0950-1991. PMID  7867500.
  • Luo, Da; Carpenter, Rosemary; Vincent, Coral; Copsey, Lucy; Coen, Enrico (1996). "Origin of floral asymmetry in Antirrhinum". Nature. 383 (6603): 794–799. Bibcode: 1996Natur.383..794L. doi: 10.1038/383794a0. ISSN  0028-0836. PMID  8893002. S2CID  2188470.
  • Bradley, Desmond; Carpenter, Rosemary; Copsey, Lucy; Vincent, Coral; Rothstein, Steven; Coen, Enrico (February 1996). "Control of inflorescence architecture in Antirrhinum". Nature. 379 (6568): 791–797. Bibcode: 1996Natur.379..791B. doi: 10.1038/379791a0. PMID  8587601. S2CID  998958.

References

  1. ^ "Award winners: Darwin Medal". Royal Society.
  2. ^ a b c Coen, E. S. (1996). "Floral symmetry". The EMBO Journal. 15 (24): 6777–6788. doi: 10.1002/j.1460-2075.1996.tb01069.x. PMC  452503. PMID  9003753.
  3. ^ "Flower Development, E Coen and R Carpenter, Cell & Developmental Biology Department - JIC UK". 20 February 2002. Archived from the original on 20 February 2002. Retrieved 25 September 2021.
  4. ^ "E.Coen and R.Caprpenter, Flower Development, Research Programme". 11 March 2002. Archived from the original on 11 March 2002. Retrieved 25 September 2021.
  5. ^ "Return of the snapdragon". Nature Plants. 5 (2): 121. 2019. doi: 10.1038/s41477-019-0377-0. ISSN  2055-0278. PMID  30737515.
  6. ^ "Past members - Flower Development, E Coen , Cell & Developmental Biology Department - JIC UK". rico-coen.jic.ac.uk. Archived from the original on 25 September 2021. Retrieved 25 September 2021.
  7. ^ Carpenter, Rosemary (1998). Studies on genetic instability in Antirrhinum majus (Thesis).
  8. ^ Harrison, Brian J; Carpenter, Rosemary (1973). "A comparison of the instabilities at the Nivea and Pallida loci in Antirrhinum majus". Heredity. 31 (3): 309–323. doi: 10.1038/hdy.1973.88. ISSN  0018-067X. S2CID  21953999.
  9. ^ Harrison, Brian J.; Carpenter, Rosemary (1 November 1979). "Resurgence of genetic instability in Antirrhinum majus". Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 63 (1): 47–66. doi: 10.1016/0027-5107(79)90103-9. ISSN  0027-5107.
  10. ^ Sommer, Hans; Carpenter, Rosemary; Harrison, Brian J.; Saedler, Heinz (1985). "The transposable element Tam3 of Antirrhinum majus generates a novel type of sequence alterations upon excision". Molecular and General Genetics. 199 (2): 225–231. doi: 10.1007/BF00330263. ISSN  0026-8925. S2CID  8399480.
  11. ^ Schwarz-Sommer, Zsuzsanna; Davies, Brendan; Hudson, Andrew (2003). "An everlasting pioneer: the story of Antirrhinum research". Nature Reviews Genetics. 4 (8): 655–664. doi: 10.1038/nrg1127. hdl: 1842/704. ISSN  1471-0056. PMID  12897777. S2CID  205482851.
  12. ^ Martin, Cathie; Carpenter, Rosemary; Sommer, Hans; Saedler, Heinz; Coen, Enrico S. (1985). "Molecular analysis of instability in flower pigmentation of Antirrhinum majus , following isolation of the pallida locus by transposon tagging". The EMBO Journal. 4 (7): 1625–1630. doi: 10.1002/j.1460-2075.1985.tb03829.x. PMC  554396. PMID  16453618.
  13. ^ Coen, Enrico S.; Carpenter, Rosemary; Martin, Cathie (1986). "Transposable elements generate novel spatial patterns of gene expression in antirrhinum majus". Cell. 47 (2): 285–296. doi: 10.1016/0092-8674(86)90451-4. PMID  3021338. S2CID  24465394.
  14. ^ Carpenter, Rosemary; Martin, Cathie; Coen, Enrico S. (1987). "Comparison of genetic behaviour of the transposable element Tam3 at two unlinked pigment loci in Antirrhinum majus". Molecular and General Genetics. 207 (1): 82–89. doi: 10.1007/BF00331494. ISSN  0026-8925. S2CID  31982611.
  15. ^ Carpenter, R; Coen, E S (1 September 1990). "Floral homeotic mutations produced by transposon-mutagenesis in Antirrhinum majus". Genes & Development. 4 (9): 1483–1493. doi: 10.1101/gad.4.9.1483. ISSN  0890-9369. PMID  1979295.
  16. ^ Coen, Enrico S.; Romero, JoséM.; Doyle, Sandra; Elliott, Robert; Murphy, George; Carpenter, Rosemary (1990). "floricaula: A homeotic gene required for flower development in antirrhinum majus". Cell. 63 (6): 1311–1322. doi: 10.1016/0092-8674(90)90426-F. PMID  1702033. S2CID  46586130.
  17. ^ Goodrich, Justin; Carpenter, Rosemary; Coen, Enrico S. (1992). "A common gene regulates pigmentation pattern in diverse plant species". Cell. 68 (5): 955–964. doi: 10.1016/0092-8674(92)90038-E. PMID  1547495. S2CID  42832523.
  18. ^ Bradley, Desmond; Carpenter, Rosemary; Sommer, Hans; Hartley, Nigel; Coen, Enrico (1993). "Complementary floral homeotic phenotypes result from opposite orientations of a transposon at the plena locus of antirrhinum". Cell. 72 (1): 85–95. doi: 10.1016/0092-8674(93)90052-R. PMID  8093684. S2CID  23878779.
  19. ^ Coen, Enrico S.; Carpenter, Rosemary (1993). "The Metamorphosis of Flowers". The Plant Cell. 5 (10): 1175–1181. doi: 10.2307/3869771. JSTOR  3869771. PMC  160351. PMID  12271021.
  20. ^ Carpenter, R; Copsey, L; Vincent, C; Doyle, S; Magrath, R; Coen, E (1995). "Control of flower development and phyllotaxy by meristem identity genes in antirrhinum". The Plant Cell. 7 (12): 2001–2011. doi: 10.1105/tpc.7.12.2001. ISSN  1040-4651. PMC  161057. PMID  8718618.
  21. ^ Luo, Da; Carpenter, Rosemary; Vincent, Coral; Copsey, Lucy; Coen, Enrico (1996). "Origin of floral asymmetry in Antirrhinum". Nature. 383 (6603): 794–799. Bibcode: 1996Natur.383..794L. doi: 10.1038/383794a0. ISSN  0028-0836. PMID  8893002. S2CID  2188470.
  22. ^ Da Luo; Carpenter, Rosemary; Copsey, Lucy; Vincent, Coral; Clark, Jennifer; Coen, Enrico (1999). "Control of Organ Asymmetry in Flowers of Antirrhinum". Cell. 99 (4): 367–376. doi: 10.1016/s0092-8674(00)81523-8. ISSN  0092-8674. PMID  10571179. S2CID  14346487.
  23. ^ Nath, Utpal; Crawford, Brian C. W.; Carpenter, Rosemary; Coen, Enrico (28 February 2003). "Genetic Control of Surface Curvature". Science. 299 (5611): 1404–1407. doi: 10.1126/science.1079354. PMID  12610308. S2CID  8059321.
  24. ^ Corley, Susie B.; Carpenter, Rosemary; Copsey, Lucy; Coen, Enrico (5 April 2005). "Floral asymmetry involves an interplay between TCP and MYB transcription factors in Antirrhinum". Proceedings of the National Academy of Sciences. 102 (14): 5068–5073. Bibcode: 2005PNAS..102.5068C. doi: 10.1073/pnas.0501340102. ISSN  0027-8424. PMC  555980. PMID  15790677.
  25. ^ Bradley, Desmond; Xu, Ping; Mohorianu, Irina-Ioana; Whibley, Annabel; Field, David; Tavares, Hugo; Couchman, Matthew; Copsey, Lucy; Carpenter, Rosemary; Li, Miaomiao; Li, Qun (17 November 2017). "Evolution of flower color pattern through selection on regulatory small RNAs". Science. 358 (6365): 925–928. Bibcode: 2017Sci...358..925B. doi: 10.1126/science.aao3526. PMID  29146812. S2CID  5060290.
  26. ^ Centre, John Innes. "How Snapdragons keep their colour: Signposting trick reveals evolutionary mechanism". phys.org. Retrieved 25 September 2021.

External links

  • Antirrhinum Stock Collection, archived images of snapdragon variants
  • CA 2230511A1  "Flowering genes" - for the CENTRORADIALIS (CEN) gene in Antirrhinum
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