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Retrovirus direct repeat 1 (dr1)
Predicted secondary structure and sequence conservation of Retro_dr1
Identifiers
SymbolRetro_dr1
Rfam RF00214
Other data
RNA type Cis-reg
Domain(s) Viruses
SO SO:0000233
PDB structures PDBe

The direct repeat 1 (dr1) element is an RNA element commonly found in the 3' UTR of Avian sarcoma, Rous sarcoma and Avian leukosis viruses ( Alpharetroviruses and Avian type C retroviruses). dr1 is required for efficient viral replication and is thought to be involved in genomic RNA packaging although this may not be its only role. [1]

References

  1. ^ Aschoff JM, Foster D, Coffin JM (September 1999). "Point mutations in the avian sarcoma/leukosis virus 3' untranslated region result in a packaging defect". Journal of Virology. 73 (9): 7421–7429. doi: 10.1128/JVI.73.9.7421-7429.1999. PMC  104269. PMID  10438832.

External links