Route 405 or Highway 405 may refer to:

Canada

• Manitoba Provincial Road 405
• Newfoundland and Labrador Route 405
• Ontario Highway 405

Costa Rica

• National Route 405

Japan

• Japan National Route 405

United Kingdom

• A405 road

United States

• Interstate 405
  • Interstate 405 (California), a bypass of Los Angeles, California
  • Interstate 405 (Oregon), a bypass of Portland, Oregon
  • Interstate 405 (Washington), a bypass of Seattle, Washington
• Florida:
  • Florida State Road 405
  • County Road 405 (Brevard County, Florida)
• Georgia State Route 405 ( unsigned designation for Interstate 95)
• Maryland Route 405
• New York:
  • New York State Route 405 (former)
  • County Route 405 (Albany County, New York)
  • County Route 405 (Erie County, New York)
• Pennsylvania Route 405
• Puerto Rico Highway 405
• Virginia State Route 405

This article includes a list of roads, streets, highways, or other routes that are associated with the same title.
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