In the solid state the lead(IV) centers are coordinated by four acetate ions, which are
bidentate, each coordinating via two oxygen atoms. The lead atom is 8 coordinate and the O atoms form a flattened
trigonal dodecahedron.[3]
Acetoxylation of benzylic, allylic and α-oxygen ether C−H bonds, for example the
photochemical conversion of
dioxane to
1,4-dioxene through the 2-acetoxy-1,4-dioxane intermediate [6] and the conversion of
α-pinene to
verbenone[7]
Lead(IV) acetate may be fatal if ingested, inhaled, or absorbed through skin. It causes irritation to skin, eyes, and respiratory tract. It is a neurotoxin. It affects the gum tissue, central nervous system, kidneys, blood, and reproductive system.
^Schürmann, M.; Huber, F. (1994). "A redetermination of lead(IV) acetate". Acta Crystallographica Section C. 50 (11): 1710–1713.
doi:
10.1107/S0108270194006438.
ISSN0108-2701.
^Baumgarten, Henry; Smith, Howard; Staklis, Andris (1975). "Reactions of amines. XVIII. Oxidative rearrangement of amides with lead tetraacetate". The Journal of Organic Chemistry. 40 (24): 3554–3561.
doi:
10.1021/jo00912a019.
^Álvarez Manzaneda, E. J.; Chahboun, R.; Cano, M. J.; Cabrera Torres, E.; Álvarez, E.; Álvarez Manzaneda, R.; Haidour, A.; Ramos López, J. M. (2006). "O3/Pb(OAc)4: a new and efficient system for the oxidative cleavage of allyl alcohols". Tetrahedron Letters. 47 (37): 6619–6622.
doi:
10.1016/j.tetlet.2006.07.020.
^Conversion of 1-allylcyclohexanol to
cyclohexanone, in the proposed
reaction mechanism the allyl group is first converted to a trioxalane according to conventional ozonolysis which then interacts with the alkoxy lead group.
^Myrboh, B.; Ila, H.; Junjappa, H. (1981). "One-Step Synthesis of Methyl Arylacetates from Acetophenones Using Lead(IV) Acetate". Synthesis. 2 (2): 126–127.
doi:
10.1055/s-1981-29358.