Monoclonal antibody | |
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Type | Whole antibody |
Source | Mouse |
Target | Glutamate carboxypeptidase II |
Clinical data | |
Trade names | Prostascint |
ATC code | |
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Indium (111In) capromab pendetide (trade name Prostascint) is used to image the extent of prostate cancer. [1] Capromab is a mouse monoclonal antibody which recognizes a protein found on both prostate cancer cells and normal prostate tissue. It is linked to pendetide, a derivative of DTPA. [2] Pendetide acts as a chelating agent for the radionuclide indium-111. Following an intravenous injection of Prostascint, imaging is performed using single-photon emission computed tomography (SPECT). [1]
Early trials with yttrium ( 90Y) capromab pendetide were also conducted. [3]