Heparan sulfate 6-O-sulfotransferase 2 is a
protein that in humans is encoded by the HS6ST2
gene.
[5]
Function
Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various
ligands to influence
cell growth, differentiation, adhesion, and migration.
This gene encodes a member of the heparan sulfate (HS)
sulfotransferase gene family, which catalyze the transfer of
sulfate to HS. Different family members and
isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene.