Gene amplification refers to a number of natural and artificial processes by which the number of copies of a
gene is increased "without a proportional increase in other genes".[1]
Artificial DNA amplification
In research or diagnosis DNA amplification can be conducted through methods such as:
Polymerase chain reaction, an easy, cheap, and reliable way to repeatedly
replicate a focused segment of DNA by polymerizing nucleotides, a concept which is applicable to numerous fields in modern biology and related sciences.[2]
Ligase chain reaction, a method that amplifies the nucleic acid used as the probe. For each of the two DNA strands, two partial probes are ligated to form the actual one; thus, LCR uses two enzymes: a
DNA polymerase (used for initial template amplification and then inactivated) and a thermostable
DNA ligase.[3]