formimidoyltransferase cyclodeaminase
Formiminotransferase cyclodeaminase homooctamer, Rattus norvegicus
Identifiers
Symbol	FTCD
Alt. names	formiminotransferase cyclodeaminase
NCBI gene	10841
HGNC	3974
OMIM	606806
RefSeq	NM_006657
UniProt	O95954
Other data
EC number	4.3.1.4
Locus	Chr. 21 q22.3
Search for Structures Swiss-model Domains InterPro

Formimidoyltransferase cyclodeaminase or formiminotransferase cyclodeaminase (symbol FTCD in humans) is an enzyme that catalyzes the conversion of formiminoglutamate and tetrahydrofolate into formiminotetrahydrofolate and glutamate.

Role in pathology

Mutations of the FTCD gene cause glutamate formiminotransferase deficiency. ^[1]

See also

• Glutamate-1-semialdehyde

References

External links

• formiminotetrahydrofolate+cyclodeaminase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)