From Wikipedia, the free encyclopedia
Endo-α-sialidase (
EC
3.2.1.129 , endo-N-acylneuraminidase , endoneuraminidase , endo-N-acetylneuraminidase , poly(α-2,8-sialosyl) endo-N-acetylneuraminidase , poly(α-2,8-sialoside) α-2,8-sialosylhydrolase , endosialidase , endo-N ) is an
enzyme with
systematic name polysialoside (2→8)-α-sialosylhydrolase .
[1]
[2]
[3]
[4]
[5]
[6]
[7] It
catalyses the following
chemical reaction :
Endohydrolysis of (2→8)-α-sialosyl linkages in oligo- or poly(sialic) acids
References
^ Finne J, Mäkelä PH (January 1985).
"Cleavage of the polysialosyl units of brain glycoproteins by a bacteriophage endosialidase. Involvement of a long oligosaccharide segment in molecular interactions of polysialic acid" . The Journal of Biological Chemistry . 260 (2): 1265–70.
doi :
10.1016/S0021-9258(20)71238-X .
PMID
3968060 .
^ Hallenbeck PC, Vimr ER, Yu F, Bassler B, Troy FA (March 1987).
"Purification and properties of a bacteriophage-induced endo-N-acetylneuraminidase specific for poly-α-2,8-sialosyl carbohydrate units" . The Journal of Biological Chemistry . 262 (8): 3553–61.
doi :
10.1016/S0021-9258(18)61387-0 .
PMID
3546309 .
^ Kitajima K, Inoue S, Inoue Y, Troy FA (December 1988).
"Use of a bacteriophage-derived endo-N -acetylneuraminidase and an equine antipolysialyl antibody to characterize the polysialyl residues in salmonid fish egg polysialoglycoproteins. Substrate and immunospecificity studies" . The Journal of Biological Chemistry . 263 (34): 18269–76.
doi :
10.1016/S0021-9258(19)81355-8 .
PMID
3142874 .
^ Kwiatkowski B, Boschek B, Thiele H, Stirm S (August 1982).
"Endo-N -acetylneuraminidase associated with bacteriophage particles" . Journal of Virology . 43 (2): 697–704.
doi :
10.1128/JVI.43.2.697-704.1982 .
PMC
256172 .
PMID
7109038 .
^ Pelkonen S, Pelkonen J, Finne J (October 1989).
"Common cleavage pattern of polysialic acid by bacteriophage endosialidases of different properties and origins" . Journal of Virology . 63 (10): 4409–16.
doi :
10.1128/JVI.63.10.4409-4416.1989 .
PMC
251059 .
PMID
2778882 .
^ Tomlinson S, Taylor PW (August 1985).
"Neuraminidase associated with coliphage E that specifically depolymerizes the Escherichia coli K1 capsular polysaccharide" . Journal of Virology . 55 (2): 374–8.
doi :
10.1128/JVI.55.2.374-378.1985 .
PMC
254943 .
PMID
3894684 .
^ Cabezas JA (August 1991).
"Some questions and suggestions on the type references of the official nomenclature (IUB) for sialidase(s) and endosialidase" . The Biochemical Journal . 278 ( Pt 1) (Pt 1): 311–2.
doi :
10.1042/bj2780311 .
PMC
1151486 .
PMID
1883340 .
External links
Activity Regulation Classification Kinetics Types