^Shkëndija played their home match at Toše Proeski Arena, Skopje, instead of their regular stadium
Ecolog Arena,
Tetovo, which did not meet UEFA requirements.
^Shakhtyor Soligorsk played their home match at Diósgyőri Stadion, Miskolc (Hungary), instead of their regular stadium
Stroitel Stadium,
Soligorsk, as in June 2021 UEFA suspended most matches to be played in Belarus, due to
European Union sanctions in response to the
Ryanair Flight 4978 incident which banned European Union airlines from flying over Belarusian airspace.[12]
^Connah's Quay Nomads played their home match at Park Avenue, Aberystwyth, instead of their regular stadium
Deeside Stadium,
Connah's Quay, which did not meet UEFA requirements.
^
abFola Esch played their third qualifying round and play-off round home matches at Stade Josy Barthel, Luxembourg City, instead of their regular stadium
Stade Émile Mayrisch,
Esch-sur-Alzette, which did not meet UEFA requirements.
^Teuta played their third qualifying round home match at Elbasan Arena, Elbasan, instead of their regular stadium
Niko Dovana Stadium,
Durrës, which did not meet UEFA requirements.
^Riga played their third qualifying round
home match at Daugava Stadium, Riga, instead of their regular
Skonto Stadium,
Riga.