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Yuanhunine
Names
IUPAC name
2,3,9-Trimethoxy-13α-methyl-13aβ-berbin-10-ol
Systematic IUPAC name
(13S ,13aR )-2,3,9-Trimethoxy-13-methyl-5,8,13,13a-tetrahydro-6H -isoquinolino[3,2-a ]isoquinolin-10-ol
Identifiers
ChemSpider
MeSH
C051427
InChI=1S/C21H25NO4/c1-12-14-5-6-17(23)21(26-4)16(14)11-22-8-7-13-9-18(24-2)19(25-3)10-15(13)20(12)22/h5-6,9-10,12,20,23H,7-8,11H2,1-4H3/t12-,20+/m0/s1
Key: PVYYNJAXBCIMNG-FKIZINRSSA-N
InChI=1/C21H25NO4/c1-12-14-5-6-17(23)21(26-4)16(14)11-22-8-7-13-9-18(24-2)19(25-3)10-15(13)20(12)22/h5-6,9-10,12,20,23H,7-8,11H2,1-4H3/t12-,20+/m0/s1
Key: PVYYNJAXBCIMNG-FKIZINRSBB
O(c1c4c(ccc1O)[C@@H]([C@@H]3c2c(cc(OC)c(OC)c2)CCN3C4)C)C
Properties
C 21 H 25 N O 4
Molar mass
355.434 g·mol−1
Solubility
Soluble in
DMSO
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
Yuanhunine is an anti-allergic
[1]
alkaloid isolated from
Corydalis .
[2]
References
^ Saito, S. Y.; Tanaka, M.; Matsunaga, K.; Li, Y.; Ohizumi, Y. (2004). "The combination of rat mast cell and rabbit aortic smooth muscle is the simple bioassay for the screening of anti-allergic ingredient from methanolic extract of Corydalis tuber". Biological & Pharmaceutical Bulletin . 27 (8): 1270–1274.
doi :
10.1248/bpb.27.1270 .
PMID
15305035 .
^
"LOTUS: Natural Products Online" . lotus.naturalproducts.net . Retrieved 2022-04-07 .