From Wikipedia, the free encyclopedia

Yu Dechao ( Chinese: 俞德超, born February 4, 1964), also known as Michael Yu, [1] is the founder and CEO of Chinese pharmaceutical company Innovent Biologics. [2] He received PhD degree in Genetics from the Chinese Academy of Sciences [3] and completed post-doctoral training in pharmaceutical chemistry at the UCSF. [4] As an inventor and owner of more than 60 patents (including 38 U.S. patents), [4] Yu established Innovent Biologics in 2011. [5] He is a professor and doctoral supervisor of Sichuan University, a visiting professor of Zhejiang University and an adjunct professor at Suzhou University, [6] the chairman of the board of the Chinese Antibody Society. [7]

Biography

Yu was the vice president of Research and Development at Applied Genetic Technologies Corporation ( NasdaqAGTC) and Calydon, Inc., [8] the latter was acquired by Cell Genesys, Inc. in 2001, where he worked for three years following the acquisition. [9] In 2011, Yu founded Innovent Biologics, and it became listed on the Main Board of the HKEX with the stock code: 01801.HK. on October 31, 2018.

Achievements in biomedicine

Yu invented and developed three "Class I" drugs in China. [10] He invented Oncorine (an oncology product), [11] which is the world's first oncolytic virus product; [12] Tyvyt (generic name: sintilimab), which is the domestically developed PD-1 antibody jointly developed by Innovent Biologics and Eli Lilly and Company, [13] and the key clinical results of Tyvyt in patients with r/r cHL have been published by the Lancet Haematology. [14] And Tyvyt has been officially approved by the National Medical Products Administration [15] for marketing in China for relapsed or refractory classical Hodgkin's lymphoma (r/r cHL) as the first approved indication. [16]

Awards and recognition

Yu Dechao was selected as "Most Influential Overseas Returnee in Life Sciences" in 2013; one of the "Top Ten Figure of Innovation in China" in 2014; "E&Y Entrepreneur of the Year in China" in 2015; "Distinguished Entrepreneur of Jiangsu Province" in 2016; [7] national "Person of the Year in Innovation for Science and Technology in 2016" in January 2017; [7] awarded as "The Seventh National Overseas Returnee Contributions Awards" in 2018. [9]

References

  1. ^ Macular Degeneration: New Insights for the Healthcare Professional: 2013 Edition: ScholarlyBrief. ScholarlyEditions. 22 July 2013. pp. 22–. ISBN  978-1-4816-5391-6.
  2. ^ "Capital Group Eyes Pre-IPO Stake in China Biotech Unicorn". Bloomberg News. Retrieved 15 January 2018.
  3. ^ "Michael Yu:High Quality Drugs Should be Affordable to Ordinary People". Chinese Academy of Sciences. Retrieved 1 December 2015.
  4. ^ a b "Recruitment program a magnet for talent". China Daily. Apr 20, 2017.
  5. ^ "Capital Group eyeing stake in China biotech unicorn". The Star (Malaysia). Retrieved 17 January 2018.
  6. ^ "关于公布江苏省第五批产业教授(兼职)" (PDF). Southeast University. Retrieved Dec 28, 2017.
  7. ^ a b c "集贤大讲坛:开发出中国老百姓用得起的高质量生物药". Zhejiang A & F University. Retrieved Apr 13, 2017.
  8. ^ Pablo Hernáiz Driever; Samuel D. Rabkin (1 January 2001). Replication-competent Viruses for Cancer Therapy. Karger Medical and Scientific Publishers. pp. 56–. ISBN  978-3-8055-7248-4.
  9. ^ a b "directors and senior management" (PDF). etnet.com. Retrieved 18 October 2018.
  10. ^ "加快迈向新药研发大国". People's Daily. Retrieved Feb 20, 2019.
  11. ^ Shuren Zhang (30 May 2016). Progress in Cancer Immunotherapy. Springer. pp. 244–. ISBN  978-94-017-7555-7.
  12. ^ Liang, M. (2018). "Oncorine, the World First Oncolytic Virus Medicine and its Update in China". Current Cancer Drug Targets. 18 (2): 171–176. doi: 10.2174/1568009618666171129221503. PMID  29189159.
  13. ^ "China Approves Tyvyt For Hodgkin's Lymphoma". Asian Scientist Magazine. Apr 20, 2017. Retrieved January 9, 2019.
  14. ^ Ansell, S. M. (2019). "Sintilimab: Another effective immune checkpoint inhibitor in classical Hodgkin lymphoma". The Lancet. Haematology. 6 (1): e2–e3. doi: 10.1016/S2352-3026(18)30210-2. PMID  30612711. S2CID  58561198.
  15. ^ "治疗霍奇金淋巴瘤的PD-1抗体药物信迪利单抗注射液获批上市". nmpa.gov.cn. Retrieved 28 December 2018.
  16. ^ Hoy, S. M. (2019). "Sintilimab: First Global Approval". Drugs. 79 (3): 341–346. doi: 10.1007/s40265-019-1066-z. PMID  30742278. S2CID  59945274.