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Polio, also called poliomyelitis, or infantile paralysis, is an infectious disease caused by the poliovirus. [1]
Polio causes muscle weakness, resulting in an inability to move in roughly one half percent of people, who are infected with the virus. [1]
This can occur over a few hours, to a few days. [1] [2]
The weakness most often involves the legs, but can also include the muscles of the head, neck, and diaphragm. [1]
Many people fully recover, [1] but there is a risk of death. About 2 to 5 percent of children, and 15 to 30 percent of adults die, if they develop muscle weakness. [1]
Another 25 percent of people infected have minor symptoms such as fever, and a sore throat, that resolve in one to two weeks [1] . Five percent have headache, neck stiffness, and pains in the arms and legs. [1] [2] About 70 percent of infections have no symptoms at all. [1]
Years after recovery , post-polio syndrome may occur with a slow development of muscle weakness, similar to the persons original symptoms. [3]
Poliovirus is usually spread from person to person through infected fecal matter entering the mouth, [1] from food or water containing human feces, and less commonly from infected saliva. [1] [2]
Those who are infected may spread the disease for up to six weeks, even if no symptoms are present. [1]
The disease may be diagnosed by finding the virus in the feces, or detecting antibodies against it in the blood. [1] The disease only occurs naturally in humans. [1]
Polio is preventable with the polio vaccine; however, multiple doses are required for it to be effective. [2]
The US Centers for Disease Control and Prevention recommends polio vaccination boosters for travelers, and those who live in countries where the disease is occurring. [4]
Once infected there is no specific treatment. [2] In 2018, there were 33 cases of wild polio, and 103 cases of vaccine-derived polio. [5] This is down from 350,000 wild cases in 1988. [2] In 2018, the disease was only spread between people in Afghanistan and Pakistan. [5]
Poliomyelitis has existed for thousands of years, with depictions of the disease in ancient art. [1] The disease was first recognized as a distinct condition by the English physician Michael Underwood in 1789, [1] and the virus that causes it was first identified in 1908 by the Austrian immunologist Karl Landsteiner. [6]
Major outbreaks started to occur in the late 19th century, in Europe and the United States. [1] In the 20th century it became one of the most worrying childhood diseases in these areas. [7]
The first polio vaccine was developed in the 1950s by Jonas Salk. [8] In 2013, the World Health Organization hoped that vaccination efforts, and early detection of cases would result in global eradication of the disease by 2018. [9]