Parent institution |
University of Oxford Wellcome Trust |
---|---|
Established | 1994 |
Director | John Todd |
Staff | 470 |
Key people | Yvonne Jones (deputy director) |
Formerly called | Wellcome Trust Center for Human Genetics |
Location | Henry Wellcome Building of Genomic Medicine,
Oxford |
Coordinates | 51°45′08″N 1°12′55″W / 51.752248°N 1.215255°W |
Website |
www |
The Wellcome Centre for Human Genetics is a human genetics research centre of the Nuffield Department of Medicine in the Medical Sciences Division, University of Oxford, funded by the Wellcome Trust among others. [1]
The centre is located at the Henry Wellcome Building of Genomic Medicine, which cost £20 million and was officially opened in June 2000 with Anthony Monaco as the director. [2] [3]
Within the WHG a number of 'cores' provide services to the researchers:
The Oxford Genomics Centre provides high throughput sequencing services, using Illumina HiSeq4000 2500 and NextSeq500 and MiSeq. [4] They also offer Oxford Nanopore MinION and PromethION sequencing. [4] There are also Array platforms for genotyping, gene expression, and methylation including Illuminia Infinium, Affymetrix and Fluidigm. [5]
The Research Computing Core provides access to computer resources including 4120 cores and 4.2 PB of storage. [6]
The Transgenics Core provides access to genetically modified mice and cell lines. [7]
Cellular Imaging Core provides microscopy facilities including fluorescence microscopy (including Fluorescence Correlation Spectroscopy ( FCS), Fluorescence Lifetime Correlation Spectroscopy ( FLCS), Fluorescence Lifetime Imaging Microscopy ( FLIM), Total Internal Reflection Fluorescence Microscopy ( TIRF), Photoactivated Localisation Microscopy ( PALM), Spectral Imaging ( SI) and Single Particle Tracking ( SPT). [8]
The WHG has been involved in many international statistical genetics advances including the Wellcome Trust Case Control Consortia (WTCCC, WTCCC2), the 1000 Genomes Project and the International HapMap Project. [9]