Main series
| Territory | Local Name | Main Broadcaster | Main Presenter | Series Premiere | Series Finale | Status |
|---|---|---|---|---|---|---|
| Argentina | " Gran Hermano" | Telefe | Mariano Peluffo | March 10, 2001 | – | Returning |
| Brazil | " Big Brother Brasil" | Rede Globo | Pedro Bial | January 29, 2002 | – | Returning |
| Chile, Ecuador & Peru | "Gran Hermano del Pacífico" | RedTV, Telesistema, ATV | Lorena Meritano | June 11, 2005 | September 4, 2005 | Ended |
| Colombia | "Gran Hermano" | Caracol TV | Víctor Mallarino | July 27, 2003 | November 10, 2003 | Ended |
| Ecuador | "Gran Hermano" | Ecuavisa | Toty Rodríguez | March 16, 2003 | July 13, 2003 | Ended |
| Mexico | "Big Brother México" | Televisa | Verónica Castro | March 10, 2001 | July 3, 2005 | Ended |
| Québec, Canada | " Loft Story" | TQS | Pierre-Yves Lord | October 5, 2003 | May 31, 2009 | Ended |
| Québec, Canada | " Big Brother" | V | Chéli Sauvé-Castonguay | March 14, 2010 | May 16, 2010 | Ended |
| United–States | " Big Brother" | CBS | Julie Chen | July 5, 2000 | – | Returning |