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I am an academic M.D. Professor Emeritus with past training and certification in Internal Medicine and Hematology but have for the past 40 years focused on basic and clinical research in the following areas:
Chemotactic factors for human and non-human
leukocytes .
Cellular
arachidonic acid metabolism and its
eicosanoid metabolites including
5-Hydroxyicosatetraenoic acid ,
20-Hydroxyeicosatetraenoic acid ,
15-Hydroxyicosatetraenoic acid ,
12-hydroxyeicosatetraenoic acid ,
5-oxo-eicosatetraenoic acid ,
20-Hydroxyeicosatetraenoic acid , and the
prostaglandins ,
leukotrienes , and
lipoxins , as well as the metabolites of
eicosapentanoic acid and
Docosahexaenoic acid (also termed
docosanoids ) such as the various
resolvins and
maresins . While not directly working with them, I am editing the pages on the
cytochrome P450 metabolites of arachidonic and other polyunsaturated fatty acids such as
20-Hydroxyeicosatetraenoic acid and the
Epoxyeicosatrienoic acids .
Cellular
linoleic acid and its metabolism and metabolites including
13-Hydroxyoctadecadienoic acid .
Other cellular
Omega-3 fatty acid and
Omega-6 fatty acid
polyunsaturated fatty acids : their consumption, metabolism, and metabolites.
Cellular
phospholipids and their metabolism and metabolites such as
platelet-activating factor and
diacylglycerols .
G protein coupled receptors for the agents cited above.
The enzymes (
lipoxygenases ,
cyclooxygenases ,
epoxygenases , monooxygenases, and
CYP450s ) and metabolic pathways which produce or inactivate these various agents
The roles played by the above agents in human diseases including
inflammation ,
allergy , and various human cancers such as those of the
blood and lymphoid tissues ,
prostate , and
breast .
I do not interact with pharmaceutical, medical, and other companies or groups that have drug and/or similar promotional interests.