Twelvemile is an unincorporated community in Madison County, in the U.S. state of Missouri. [1]
A post office called Twelve Mile was established in 1876, and remained in operation until 1910. [2] The community took its name from being 12 miles from Fredericktown, Missouri, and gave its name to the creek that runs by it, Twelvemile Creek. [3]
37°21′58″N 90°21′47″W / 37.36611°N 90.36306°W