| Crohn's disease | Ulcerative colitis | |
|---|---|---|
| Terminal ileum involvement | Commonly | Seldom |
| Colon involvement | Usually | Always |
| Rectum involvement | Seldom | Usually (95%) [1] |
| Involvement around the anus |
Common [2] | Seldom |
| Bile duct involvement | No increase in rate of primary sclerosing cholangitis | Higher rate [3] |
| Distribution of disease | Patchy areas of inflammation (skip lesions) | Continuous area of inflammation [1] |
| Endoscopy | Deep geographic and serpiginous (snake-like) ulcers | Continuous ulcer |
| Depth of inflammation | May be transmural, deep into tissues [2] [4] | Shallow, mucosal |
| Stenosis | Common | Seldom |
| Granulomas on biopsy | May have non- necrotizing non-peri- intestinal crypt granulomas [2] [5] [6] | Non-peri- intestinal crypt granulomas not seen [7] |
The tables in this series compare Crohn's disease and ulcerative colitis, the main types of inflammatory bowel disease, and are used in both articles.
Templates in this series
- {{ Complications of CD vs. UC}}
- {{ Findings in CD vs. UC}}
- {{ Risk factors in CD vs. UC}}
- {{ Pathophysiology in CD vs. UC}}
- {{ Symptoms in CD vs. UC}}
- {{ Treatment in CD vs. UC}}
References
- ^ a b Rubin DT, Ananthakrishnan AN, Siegel CA, Sauer BG, Long MD (March 2019). "ACG Clinical Guideline: Ulcerative Colitis in Adults". The American Journal of Gastroenterology. 114 (3): 384–413. doi: 10.14309/ajg.0000000000000152. PMID 30840605. S2CID 73473272.
- ^
a
b
c Hanauer SB, Sandborn W (March 2001).
"Management of Crohn's disease in adults". The American Journal of Gastroenterology. 96 (3): 635–43.
doi:
10.1111/j.1572-0241.2001.3671_c.x (inactive 31 January 2024).
PMID
11280528.
S2CID
31219115.
{{ cite journal}}: CS1 maint: DOI inactive as of January 2024 ( link) - ^ Broomé U, Bergquist A (February 2006). "Primary sclerosing cholangitis, inflammatory bowel disease, and colon cancer". Seminars in Liver Disease. 26 (1): 31–41. doi: 10.1055/s-2006-933561. PMID 16496231. S2CID 260320940.
- ^ Baumgart DC, Sandborn WJ (May 2007). "Inflammatory bowel disease: clinical aspects and established and evolving therapies". Lancet. 369 (9573): 1641–57. doi: 10.1016/S0140-6736(07)60751-X. PMID 17499606. S2CID 35264387.
- ^ Shepherd NA (August 2002). "Granulomas in the diagnosis of intestinal Crohn's disease: a myth exploded?". Histopathology. 41 (2): 166–8. doi: 10.1046/j.1365-2559.2002.01441.x. PMID 12147095. S2CID 36907992.
- ^ Mahadeva U, Martin JP, Patel NK, Price AB (July 2002). "Granulomatous ulcerative colitis: a re-appraisal of the mucosal granuloma in the distinction of Crohn's disease from ulcerative colitis". Histopathology. 41 (1): 50–5. doi: 10.1046/j.1365-2559.2002.01416.x. PMID 12121237. S2CID 29476514.
- ^ DeRoche TC, Xiao SY, Liu X (August 2014). "Histological evaluation in ulcerative colitis". Gastroenterology Report. 2 (3): 178–92. doi: 10.1093/gastro/gou031. PMC 4124271. PMID 24942757.