Stage-specific embryonic antigen 3 (SSEA-3) is a
glycosphingolipid, specifically, an
oligosaccharide composed of five
carbohydrate units connected to a
sphingolipid. Sphingolipids were originally discovered in 1884 by
Johann Ludwig Wilhelm Thudichum who named them after the
Sphinx of
Greek mythology in reference to the unresolved riddle of their function.[1] It is now known that sphingolipids function as key players in cell signaling [2] and the SSEA-3 molecule as a whole plays a key role in identifying many types of
mammalian cells with
pluripotent and
stem cell-like characteristics.[3][4]