Spanish colonization of the Americas
|Part of a series on|
of the Americas
The Spanish colonization of the Americas began under the Crown of Castile and spearheaded by the Spanish conquistadors. The Americas were invaded and incorporated into the Spanish Empire, with the exception of Brazil, United States, Canada, and some small regions in South America and the Caribbean. The crown created civil and religious structures to administer this vast territory. The main motivations for colonial expansion were profit and the spread of Catholicism through indigenous conversions.
Beginning with the 1492 arrival of Christopher Columbus in the Caribbean and gaining control over more territory for over three centuries, the Spanish Empire would expand across the Caribbean Islands, half of South America, most of Central America and much of North America. It is estimated that during the colonial period (1492–1832), a total of 1.86 million Spaniards settled in the Americas and a further 3.5 million immigrated during the post-colonial era (1850–1950); the estimate is 250,000 in the 16th century, and most during the 18th century as immigration was encouraged by the new Bourbon Dynasty.  It has been estimated that over 1.86 million Spaniards emigrated to Latin America in the period between 1492 and 1824, with millions more continuing to immigrate following independence.[ citation needed]
By contrast, the indigenous population plummeted by an estimated 80% in the first century and a half following Columbus's voyages, primarily through the spread of Afro-Eurasian diseases.  This has been argued to be the first large-scale act of genocide in the modern era.  One can question whether the huge drop in population be considered genocide (a deliberate consciousness effort to erase a group(s) of people from the earth), since no one at the time knew about the unseen agents which caused the death of millions. Racial mixing was a central process in the Spanish colonization of the Americas, and ultimately led to the Latin American identity, which combines African, Hispanic, and Native American cultures.[ citation needed]
The Habsburg dynasty squandered the American riches in pointless wars across Europe, defaulted on their debt several times, and left Spain bankrupt. In the early 19th century, the Spanish American wars of independence resulted in the secession and subsequent balkanization of most Spanish territories in the Americas, except for Cuba and Puerto Rico, which were finally lost to Spain in 1898, following the Spanish–American War. The loss of these territories ended Spanish rule in the Americas.
The expansion of Spain’s territory took place under the Catholic Monarchs Isabella of Castile, Queen of Castile and her husband King Ferdinand, King of Aragon, whose marriage marked the beginning of Spanish power beyond the Iberian peninsula. They pursued a policy of joint rule of their kingdoms and created the initial stage of a single Spanish monarchy, completed under the eighteenth-century Bourbon monarchs. The first expansion of territory was the conquest of the Muslim Kingdom of Granada on January 1, 1492, the culmination of the Christian Reconquest of the Iberian peninsula, held by the Muslims since 711. On March 31, 1492, the Catholic Monarch ordered the expulsion of the Jews in Spain who refused to convert to Christianity. On October 12, 1492, Genoese mariner Christopher Columbus made landfall in the Western Hemisphere. 
Even though Castile and Aragon were ruled jointly by their respective monarchs, they remained separate kingdoms so that when the Catholic Monarchs gave official approval for the plans for Columbus’s voyage to reach "the Indies" by sailing West, the funding came from the queen of Castile. The profits from Spanish expedition flowed to Castile. The Kingdom of Portugal authorized a series of voyages down the coast of Africa and when they rounded the southern tip, were able to sail to India and further east. Spain sought similar wealth, and authorized Columbus’s voyage sailing west. Once the Spanish settlement in the Caribbean occurred, Spain and Portugal formalized a division of the world between them in the 1494 Treaty of Tordesillas.  The deeply pious Isabella saw the expansion of Spain's sovereignty inextricably paired with the evangelization of non-Christian peoples, the so-called “spiritual conquest” with the military conquest. Pope Alexander VI in a 4 May 1493 papal decree, Inter caetera, divided rights to lands in the Western Hemisphere between Spain and Portugal on the proviso that they spread Christianity.  These formal arrangements between Spain and Portugal and the pope were ignored by other European powers.
The Spanish expansion has sometimes been succinctly summed up as "gold, glory, God." The search for material wealth, the enhancement of the conquerors' and the crown's position, and the expansion Christianity. In the extension of Spanish sovereignty to its overseas territories, authority for expeditions (entradas) of discovery, conquest, and settlement resided in the monarchy.  Expeditions required authorization by the crown, which laid out the terms of such expedition.Virtually all expeditions after the Columbus voyages, which were funded by the crown of Castile, were done at the expense of the leader of the expedition and its participants. Although often the participants, conquistadors, are now termed “soldiers”, they were not paid soldiers in ranks of an army, but rather soldiers of fortune, who joined an expedition with the expectation of profiting from it. The leader of an expedition, the adelantado was a senior with material wealth and standing who could persuade the crown to issue him a license for an expedition. He also had to attract participants to the expedition who staked their own lives and meager fortunes on the expectation of the expedition’s success. The leader of the expedition pledged the larger share of capital to the enterprise, which in many ways functioned as a commercial firm. Upon success of the expedition, the spoils of war were divvied up in proportion to the amount a participant initially staked, with the leader receiving the largest share. Participants supplied their own armor and weapons, and those who had a horse received two shares, one for himself, the second recognizing the value of the horse as a machine of war.   For the conquest era, two names of Spaniards are generally known because they led the conquests of high indigenous civilizations, Hernán Cortés, leader of the expedition that conquered the Aztecs of Central Mexico, and Francisco Pizarro, leader of the conquest of the Inca in Peru.
Until his dying day, Columbus was convinced that he had reached Asia, the Indies. From that misperception the Spanish called the indigenous peoples of the Americas, "Indians" (indios), lumping a multiplicity of civilizations, groups, and individuals into a single category of The Other. The Spanish royal government called its overseas possessions "The Indies" until its empire dissolved in the nineteenth century. Patterns set in this early period of exploration and colonization were to endure as Spain expanded further, even as the region became less important in the overseas empire after the conquests of Mexico and Peru. 
In the Caribbean, there was no large-scale Spanish conquest of indigenous peoples, but there was indigenous resistance. Columbus made four voyages to the West Indies as the monarchs granted Columbus vast powers of governance over this unknown part of the world. The crown of Castile financed more of his trans-Atlantic journeys, a pattern they would not repeat elsewhere. Effective Spanish settlement began in 1493, when Columbus brought livestock, seeds, agricultural equipment. The first settlement of La Navidad, a crude fort built on his first voyage in 1492, had been abandoned by the time he returned in 1493. He then founded the settlement of Isabela on the island they named Hispaniola (now divided into Haiti and the Dominican Republic).
Spanish explorations of other islands in the Caribbean and what turned out to be the mainland of South and Central America occupied them for over two decades. Columbus had promised that the region he now controlled held huge treasure in the form of gold and spices. Spanish settlers found relatively dense populations of indigenous peoples, who were agriculturalists living in villages ruled by leaders not part of a larger integrated political system. For the Spanish, these populations were there for their exploitation, to supply their own settlements with foodstuffs, but more importantly for the Spanish, to extract mineral wealth or produce another valuable commodity for Spanish enrichment. The labor of dense populations of Tainos were allocated to Spanish settlers in an institution known as the encomienda, where particular indigenous settlements were awarded to individual Spaniards. There was surface gold found in early islands, and holders of encomiendas put the indigenous to work panning for it. For all practical purposes this was slavery. Queen Isabel put an end to formal slavery, declaring the indigenous to be vassals of the crown, but Spaniards' exploitation continued. The Taino population on Hispaniola went from hundreds of thousands or millions –- the estimates by scholars vary widely -- but in the mid 1490s, they were practically wiped out. Disease and overwork, disruption of family life and the agricultural cycle (which caused severe food shortages to Spaniards dependent on them) rapidly decimated the indigenous population. From the Spanish viewpoint their source of labor and viability of their own settlements was at risk. After the collapse of Taino population of Hispaniola, Spaniards took to slave raiding and settlement on nearby islands, including Cuba, Puerto Rico, and Jamaica, replicating the demographic catastrophe there as well.
Dominican friar Antonio de Montesinos denounced Spanish cruelty and abuse in a sermon in 1511, which comes down to us in the writings of Dominican friar Bartolomé de las Casas. In 1542 Las Casas wrote a damning account of this genocide, A Short Account of the Destruction of the Indies. It was translated quickly to English and became the basis for the anti-Spanish writings, collectively known as the Black Legend. 
The first mainland explorations by Spaniards were followed by a phase of inland expeditions and conquest. In 1500 the city of Nueva Cádiz was founded on the island of Cubagua, Venezuela, followed by the founding of Santa Cruz by Alonso de Ojeda in present-day Guajira peninsula. Cumaná in Venezuela was the first permanent settlement founded by Europeans in the mainland Americas,  in 1501 by Franciscan friars, but due to successful attacks by the indigenous people, it had to be refounded several times, until Diego Hernández de Serpa's foundation in 1569. The Spanish founded San Sebastián de Uraba in 1509 but abandoned it within the year. There is indirect evidence that the first permanent Spanish mainland settlement established in the Americas was Santa María la Antigua del Darién. 
Spaniards spent over 25 years in the Caribbean where their initial high hopes of dazzling wealth gave way to continuing exploitation of disappearing indigenous populations, exhaustion of local gold mines, initiation of cane sugar cultivation as an export product, and importation of African slaves as a labor force. Spaniards continued to expand their presence in the circum-Caribbean region with expeditions. One was by Francisco Hernández de Córdoba in 1517, another by Juan de Grijalva in 1518, which brought promising news of possibilities there.   Even by the mid 1510s, the western Caribbean was largely unexplored by Spaniards. A well-connected settler in Cuba, Hernán Cortés received authorization in 1519 by the governor of Cuba to form an expedition of exploration-only to this far western region. That expedition was to change world history.
The Spanish conquest of the Aztec empire (1519-1521) was an epic event in history. Spaniards found the bonanza they long sought: great material wealth. Unlike Spanish expansion in the Caribbean, which involved limited armed combat and sometimes the participation of indigenous allies, the conquest of central Mexico was protracted and necessitated indigenous allies who chose to participate for their own purposes. Five hundred Spaniards did not topple the Aztec Empire alone. The empire was a fragile confederation of city-states. Spaniards persuaded the leaders of subordinate city-states and one city-state never conquered by the Aztecs, Tlaxcala, to join them in huge numbers, with thousands, perhaps tens of thousands of indigenous warriors. The conquest of central Mexico is one of the best documented events in world history, with accounts the by expedition leader Hernán Cortés, many other Spanish conquistadors, including Bernal Díaz del Castillo, indigenous allies from the city-states altepetl of Tlaxcala, Texcoco, and Huexotzinco, but also importantly, the defeated of Tenochtitlan, the Aztec capital. What can be called the visions of the vanquished, indigenous accounts written in the sixteenth century, are a rare case of history being written by those other than the victors.   
The capture of the Aztec emperor Moctezuma II by Cortés was not a brilliant stroke of innovation, but came from the playbook that the Spanish developed during their period in the Caribbean. The composition of the expedition was the standard pattern, with a senior leader, and participating men investing in the enterprise with the full expectation of rewards if they did not lose their lives. Cortés’s seeking indigenous allies was a typical tactic of warfare: divide and conquer. But the indigenous allies had much to gain by throwing off Aztec rule. For the Spaniards’ Tlaxcalan allies, their crucial support gained them enduring political legacy into the modern era, the Mexican state of Tlaxcala.  
The conquest of central Mexico sparked further Spanish conquests, following the pattern of conquered and consolidated regions being the launching point for further expeditions. These were often led by secondary leaders, such as Pedro de Alvarado. Later conquests in Mexico were protracted campaigns with less spectacular results than the conquest of the Aztecs. The Spanish conquest of Yucatán, the Spanish conquest of Guatemala, the conquest of the Tarascans/Purépecha of Michoacan, the war of Mexico's west, and the Chichimeca War in northern Mexico expanded Spanish control over territory and indigenous populations.     But not until the Spanish conquest of Peru was the conquest of the Aztecs matched in scope by the victory over the Inca empire in 1532.
In 1532 at the Battle of Cajamarca a group of Spaniards under Francisco Pizarro and their indigenous Andean Indian auxiliaries native allies ambushed and captured the Emperor Atahualpa of the Inca Empire. It was the first step in a long campaign that took decades of fighting to subdue the mightiest empire in the Americas. In the following years Spain extended its rule over the Empire of the Inca civilization.
The Spanish took advantage of a recent civil war between the factions of the two brothers Emperor Atahualpa and Huáscar, and the enmity of indigenous nations the Incas had subjugated, such as the Huancas, Chachapoyas, and Cañaris. In the following years the conquistadors and indigenous allies extended control over Greater Andes Region. The Viceroyalty of Perú was established in 1542. The last Inca stronghold was conquered by the Spanish in 1572.
Peru was the last territory in the continent under Spanish rule, which ended on 9 December 1824 at the Battle of Ayacucho (Spanish rule continued until 1898 in Cuba and Puerto Rico).
Chile was explored by Spaniards based in Peru, where Spaniards found the fertile soil and mild climate attractive. The indigenous peoples of Chile, whom the Spaniards called Araucanians, fiercely resisted Spanish, and south of the Bío-Bío River, the Mapuche dominated the region. The Spanish did establish the settlement of Chile in 1541, founded by Pedro de Valdivia. With a hostile indigenous population, no obvious mineral or other exploitable resources, and little strategic value, Chile was a fringe area of colonial Spanish America, hemmed in geographically by the Andes to the east, Pacific Ocean to the west, and indigenous to the south. 
Between 1537 and 1543, six[ citation needed] Spanish expeditions entered highland Colombia, conquered the Muisca Confederation, and set up the New Kingdom of Granada ( Spanish: Nuevo Reino de Granada). Gonzalo Jiménez de Quesada was the leading conquistador with his brother Hernán second in command.  It was governed by the president of the Audiencia of Bogotá, and comprised an area corresponding mainly to modern-day Colombia and parts of Venezuela. The conquistadors originally organized it as a captaincy general within the Viceroyalty of Peru. The crown established the audiencia in 1549. Ultimately, the kingdom became part of the Viceroyalty of New Granada first in 1717 and permanently in 1739. After several attempts to set up independent states in the 1810s, the kingdom and the viceroyalty ceased to exist altogether in 1819 with the establishment of Gran Colombia. 
Venezuela was first visited by Europeans during the 1490s, when Columbus was in control of the region, and the region was a source for indigenous slaves for Spaniards in Cuba and Hispaniola, since the Spanish destruction of the local indigenous population. There were few permanent settlements, but Spaniards settled the coastal islands of Cubagua and Margarita to exploit the pearl beds. Western Venezuela’s history took an atypical direction in 1528, when Spain’s first Hapsburg monarch, Charles I granted rights to colonize to the German banking family of the Welsers. Charles sought to be elected Holy Roman Emperor and was willing to pay whatever it took to achieve that. He became deeply indebted to the German Welser and Fugger banking families. To satisfy his debts to the Welsers, he granted them the right to colonize and exploit western Venezuela, with the proviso that they found two towns with 300 settlers each and construct fortifications. They established the colony of Klein-Venedig in 1528. They founded the towns of Coro and Maracaibo. They were aggressive in making their investment pay, alienating the indigenous populations and Spaniards alike. Charles revoked the grant in 1545, ending the episode of German colonization.  
Argentina was not conquered or later exploited in the grand fashion of central Mexico or Peru, since the indigenous population was sparse and there were no precious metals or other valuable resource. Although today Buenos Aires at the mouth of Rio de la Plata is a major metropolis, it held no interest for Spaniards and the 1535-36 settlement failed and was abandoned by 1541. Pedro de Mendoza and Domingo Martínez de Irala, who led the original expedition, went inland and founded Asunción, Paraguay, which became the Spaniards' base. A second (and permanent) settlement was established in 1580 by Juan de Garay, who arrived by sailing down the Paraná River from Asunción, now the capital of Paraguay.  Exploration from Peru resulted in the foundation of Tucumán in what is now northwest Argentina. 
The spectacular conquests of central Mexico (1519-21) and Peru (1532) sparked Spaniards' hopes of finding yet another high civilization. Expeditions continued into the 1540s and regional capitals founded by the 1550s. Among the most notable expeditions are Hernando de Soto into southeast North America, leaving from Cuba (1539-42); Francisco Vázquez de Coronado to northern Mexico (1540-42), and Gonzalo Pizarro to Amazonia, leaving from Quito, Ecuador (1541-42).  In 1561, Pedro de Ursúa led an expedition of some 370 Spanish (including women and children) into Amazonia to search for El Dorado. Far more famous now is Lope de Aguirre, who led a mutiny against Ursúa, who was murdered. Aguirre subsequently wrote a letter to Philip II bitterly complaining about the treatment of conquerors like himself in the wake of the assertion of crown control over Peru.  An earlier expedition was that left in 1527 was led by Pánfilo Naváez, whose was killed early on. Survivors continuing to travel among indigenous groups in the North American south and southwest until 1536. Álvar Núñez Cabeza de Vaca was one of four survivors of that expedition, writing an account of it.  The crown later sent him to Asunción, Paraguay to be adelantado there. Expeditions continued to explore territories in hopes of finding another Aztec or Inca empire, with no further luck. Francisco de Ibarra led an expedition from Zacatecas in northern New Spain, and founded Durango.  Juan de Oñate expanded Spanish sovereignty over what is now New Mexico.  He is a controversial figure in the current era, with an equestrian statue commemorating him removed from public display in 2020. 
Two major factors affected the density of Spanish settlement in the long term. One was the presence or absence of dense, hierarchically organized indigenous populations that could be made to work. The other was the presence or absence of an exploitable resource for the enrichment of settlers. Best was gold, but silver was found in abundance.
The two main areas of Spanish settlement after 1550 were Mexico and Peru, the sites of the Aztec and Inca indigenous civilizations. Equally important, rich deposits of the valuable metal silver. Spanish settlement in Mexico “largely replicated the organization of the area in preconquest times” while in Peru, the center of the Incas was too far south, too remote, and at too high an altitude for the Spanish capital. The capital Lima was built near the Pacific coast.  The capitals of Mexico and Peru, Mexico City and Lima came to have large concentrations of Spanish settlers and became the hubs of royal and ecclesiastical administration, large commercial enterprises and skilled artisans, and centers of culture. Although Spaniards had hoped to find vast quantities of gold, the discovery of large quantities of silver became the motor of the Spanish colonial economy, a major source of income for the Spanish crown, and transformed the international economy. Mining regions in both Mexico were remote, outside the zone of indigenous settlement in central and southern Mexico Mesoamerica, but mines in Zacatecas (founded 1548) and Guanajuato (founded 1548) were key hubs in the colonial economy. In Peru, silver was found in a single silver mountain, the Cerro Rico de Potosí, still producing silver in the 21st century. Potosí (founded 1545) was in the zone of dense indigenous settlement, so that labor could be mobilized on traditional patterns to extract the ore. An important element for productive mining was mercury for processing high grade ore. Peru had a source in Huancavelica (founded 1572), while Mexico had to rely on mercury imported from Spain.
The Spanish founded towns in the Caribbean, on Hispaniola and Cuba, on a pattern that became spatially similar throughout Spanish America. A central plaza had the most important buildings on the four sides, especially buildings for royal officials and the main church. A checker board pattern radiated outward. Residences of the officials and elites were closest to the main square. Once on the mainland, where there were dense indigenous populations in urban settlements, the Spanish could build a Spanish settlement on the same site, dating its foundation to when that occurred. Often they erected a church on the site of an indigenous temple. They replicated the existing indigenous network of settlements, but added a port city. The Spanish network needed a port city so that inland settlements could be connected by sea to Spain. In Mexico, the Hernán Cortés and the men of his expedition founded of the port town of Veracruz in 1519 and constituted themselves as the town councilors, as a means to throw off the authority of the governor of Cuba, who did not authorize an expedition of conquest. start of the conquest of central Mexico; once the Aztec empire was toppled, they founded Mexico City on the ruins of the Aztec capital. Their central official and ceremonial area was built on top of Aztec palaces and temples. In Peru, Spaniards founded the city of Lima as their capital and its nearby port of Callao, rather than the high-altitude site of Cuzco, the center of Inca rule. Spaniards established a network of settlements in areas they conquered and controlled. Important ones include Santiago de Guatemala (1524); Puebla (1531); Querétaro (ca. 1531); Guadalajara (1531-42); Valladolid (now Morelia), (1529-41); Antequera (now Oaxaca(1525-29); Campeche (1541); and Mérida. In southern Central and South America, settlements were founded in Panama (1519); León, Nicaragua (1524); Cartagena (1532); Piura (1532); Quito (1534); Trujillo (1535); Cali (1537) Bogotá (1538); Quito (1534); Cuzco 1534); Lima (1535); Tunja, (1539); Huamanga 1539; Arequipa (1540); Santiago de Chile (1544) and Concepción, Chile (1550). Settled from the south were Buenos Aires (1536, 1580); Asunción (1537); Potosí (1545); La Paz, Bolivia (1548); and Tucumán (1553). 
The Columbian Exchange was as significant as the clash of civilizations.   Arguably the most significant introduction was diseases brought to the Americas, which devastated indigenous populations in a series of epidemics. The loss of indigenous population had a direct impact on Spaniards as well, since increasingly they saw those populations as a source of their own wealth, disappearing before their eyes. 
In the first settlements in the Caribbean, the Spaniards deliberately brought animals and plants that transformed the ecological landscape. Pigs, cattle, sheep, goats, and chickens allowed Spaniards to eat a diet with which they were familiar. But the importation of horses transformed warfare for both the Spaniards and the indigenous. Where the Spaniards had exclusive access to horses in warfare, they had a advantage over indigenous warriors on foot. They were initially a scarce commodity, but horse breeding became an active industry. Horses that escaped Spanish control were captured by indigenous; many indigenous also raided for horses. Mounted indigenous warriors were significant foes for Spaniards. The Chichimeca in northern Mexico, the Comanche in the northern Great Plains and the Mapuche in southern Chile and the pampas of Argentina resisted Spanish conquest. For Spaniards, the fierce Chichimecas barred them for exploiting mining resources in northern Mexico. Spaniards waged a fifty-year war (ca. 1550-1600) to subdue them, but peace was only achieved by Spaniards’ making significant donations of food and other commodities the Chichimeca demanded. "Peace by purchase" ended the conflict.  In southern Chile and the pampas, the Araucanians (Mapuche) prevented further Spanish expansion. The image of mounted Araucanians capturing and carrying off white women was the embodiment of Spanish ideas of civilization and barbarism.
Cattle multiplied quickly in areas where little else could turn a profit for Spaniards, including northern Mexico and the Argentine pampas. The introduction of sheep production was an ecological disaster in places where they were raised in great numbers, since they ate vegetation to the ground, preventing the regeneration of plants. 
The Spanish brought new crops for cultivation. They preferred wheat cultivation to indigenous sources of carbohydrates: casava, maize (corn), and potatoes, initially importing seeds from Europe and planting in areas where plow agriculture could be utilized, such as the Mexican Bajío. They also imported cane sugar, which was a high value crop in the early Spanish America. Spaniards also imported citrus trees, establishing orchards of oranges, lemons, and limes, and grapefruit. Other imports were figs, apricots, cherries, pears, and peaches among others. The exchange did not go one way. Important indigenous crops that transformed Europe were the potato and maize, which produced abundant crops that led to the expansion of populations in Europe. Chocolate (Nahuatl: chocolatl) and vanilla were cultivated in Mexico and imported to Europe. Among the foodstuffs that became staples in European cuisine and could be grown there were [[tomato]es, squashes, bell peppers, and to a lesser extent in Europe chili peppers; also nuts of various kinds: Walnuts, cashews, pecans, and peanuts.
The empire in the Indies was a newly established dependency of the kingdom of Castile alone, so crown power was not impeded by any existing cortes (i.e. parliament), administrative or ecclesiastical institution, or seigneurial group.  The crown sought to establish and maintain control over its overseas possessions through a complex, hierarchical bureaucracy, which in many ways was decentralized. The crown asserted is authority and sovereignty of the territory and vassals it claimed, collected taxes, maintained public order, meted out justice, and established policies for governance of large indigenous populations. Many institutions established in Castile found expression in The Indies from the early colonial period. Spanish universities expanded to train lawyer-bureaucrats (letrados) for administrative positions in Spain and its overseas empire.
The end of the Habsburg dynasty in 1700 saw major administrative reforms in the eighteenth century under the Bourbon monarchy, starting with the first Spanish Bourbon monarch, Philip V (r. 1700-1746) and reaching its apogee under Charles III (r. 1759-1788). The reorganization of administration has been called "a revolution in government."  Reforms sought to centralize government control through reorganization of administration, reinvigorate the economies of Spain and the Spanish empire through changes in mercantile and fiscal policies, defend Spanish colonies and territorial claims through the establishment of a standing military, undermine the power of the Catholic church, and rein in the power of the American-born elites. 
The crown relied on ecclesiastics as important councilors and royal officials in the governance of their overseas territories. Archbishop Juan Rodríguez de Fonseca, Isabella's confessor, was tasked with reining in Columbus's independence. He strongly influenced the formulation of colonial policy under the Catholic Monarchs, and was instrumental in establishing the Casa de Contratación (House of Trade) (1503), which enabled crown control over trade and immigration. Ovando fitted out Magellan's voyage of circumnavigation, and became the first President of the Council of the Indies in 1524.  Ecclesiastics also functioned as administrators overseas in the early Caribbean period, particularly Frey Nicolás de Ovando, who was sent to investigate the administration of Francisco de Bobadilla, the governor appointed to succeed Christopher Columbus.  Later ecclesiastics served as interim viceroys, general inspectors (visitadores), and other high posts.
The crown established control over trade and emigration to the Indies with the 1503 establishment the Casa de Contratación (House of Trade) in Seville. Ships and cargoes were registered, and emigrants vetted to prevent migration of anyone not of old Christian heritage, (i.e., with no Jewish or Muslim ancestry), and facilitated the migration of families and women.  In addition, the Casa de Contratación took charge of the fiscal organization, and of the organization and judicial control of the trade with the Indies. 
The politics of asserting royal authority to oppose Columbus resulted in the suppression of his privileges and the creation of territorial governance under royal authority. These governorates, also called as provinces, were the basic of the territorial government of the Indies,  and arose as the territories were conquered and colonized.  To carry out the expedition (entrada), which entailed exploration, conquest, and initial settlement of the territory, the king, as sovereign, and the appointed leader of an expedition ( adelantado) agreed to an itemized contract (capitulación), with the specifics of the conditions of the expedition in a particular territory. The individual leaders of expeditions assumed the expenses of the venture and in return received as reward the grant from the government of the conquered territories;  and in addition, they received instructions about treating the indigenous peoples. 
After the end of the period of conquests, it was necessary to manage extensive and different territories with a strong bureaucracy. In the face of the impossibility of the Castilian institutions to take care of the New World affairs, other new institutions were created. 
As the basic political entity it was the governorate, or province. The governors exercised judicial ordinary functions of first instance, and prerogatives of government legislating by ordinances.  To these political functions of the governor, it could be joined the military ones, according to military requirements, with the rank of Captain general.  The office of captain general involved to be the supreme military chief of the whole territory and he was responsible for recruiting and providing troops, the fortification of the territory, the supply and the shipbuilding. 
Provinces in the Spanish Empire had a royal treasury controlled by a set of oficiales reales (royal officials). The officials of the royal treasury included up to four positions: a tesorero (treasurer), who guarded money on hand and made payments; a contador (accountant or comptroller), who recorded income and payments, maintained records, and interpreted royal instructions; a factor, who guarded weapons and supplies belonging to the king, and disposed of tribute collected in the province; and a veedor (overseer), who was responsible for contacts with native inhabitants of the province, and collected the king's share of any war booty. The treasury officials were appointed by the king, and were largely independent of the authority of the governor. Treasury officials were generally paid out of the income from the province and were normally prohibited from engaging in personal income-producing activities. 
Beginning in 1522 in the newly conquered Mexico, government units in the Spanish Empire had a royal treasury controlled by a set of oficiales reales (royal officials). There were also sub-treasuries at important ports and mining districts. The officials of the royal treasury at each level of government typically included two to four positions: a tesorero (treasurer), the senior official who guarded money on hand and made payments; a contador (accountant or comptroller), who recorded income and payments, maintained records, and interpreted royal instructions; a factor, who guarded weapons and supplies belonging to the king, and disposed of tribute collected in the province; and a veedor (overseer), who was responsible for contacts with native inhabitants of the province, and collected the king's share of any war booty. The veedor, or overseer, position quickly disappeared in most jurisdictions, subsumed into the position of factor. Depending on the conditions in a jurisdiction, the position of factor/veedor was often eliminated, as well. 
The treasury officials were appointed by the king, and were largely independent of the authority of the viceroy, audiencia president or governor. On the death, unauthorized absence, retirement or removal of a governor, the treasury officials would jointly govern the province until a new governor appointed by the king could take up his duties. Treasury officials were supposed to be paid out of the income from the province, and were normally prohibited from engaging in income-producing activities. 
The protection of the indigenous populations from enslavement and exploitation by Spanish settlers were established in the Laws of Burgos, 1512–1513. The laws were the first codified set of laws governing the behavior of Spanish settlers in the Americas, particularly with regards to treatment of native Indians in the institution of the encomienda. They forbade the maltreatment of natives, and endorsed the Indian Reductions with attempts of conversion to Catholicism.  Upon their failure to effectively protect the indigenous and following the Spanish conquest of the Aztec Empire and the Spanish conquest of Peru, more stringent laws to control conquerors' and settlers' exercise of power, especially their maltreatment of the indigenous populations, were promulgated, known as the New Laws (1542). The crown aimed to prevent the formation of an aristocracy in the Indies not under crown control.
Queen Isabel was the first monarch that laid the first stone for the protection of the indigenous peoples in her testament in which the Catholic monarch prohibited the enslavement of the indigenous peoples of the Americas.  Then the first such in 1542; the legal thought behind them was the basis of modern International law. 
The Valladolid debate (1550–1551) was the first moral debate in European history to discuss the rights and treatment of a colonized people by colonizers. Held in the Colegio de San Gregorio, in the Spanish city of Valladolid, it was a moral and theological debate about the colonization of the Americas, its justification for the conversion to Catholicism and more specifically about the relations between the European settlers and the natives of the New World. It consisted of a number of opposing views about the way natives were to be integrated into colonial life, their conversion to Christianity and their rights and obligations. According to the French historian Jean Dumont The Valladolid debate was a major turning point in world history “In that moment in Spain appeared the dawn of the human rights”. 
The indigenous populations in the Caribbean became the focus of the crown in its roles as sovereigns of the empire and patron of the Catholic Church. Spanish conquerors holding grants of indigenous labor in encomienda ruthlessly exploited them. A number of friars in the early period came to the vigorous defense of the indigenous populations, who were new converts to Christianity. Prominent Dominican friars in Santo Domingo, especially Antonio de Montesinos and Bartolomé de Las Casas denounced the maltreatment and pressed the crown to act to protect the indigenous populations. The crown enacted Laws of Burgos (1513) and the Requerimiento to curb the power of the Spanish conquerors and give indigenous populations the opportunity to peacefully embrace Spanish authority and Christianity. Neither was effective in its purpose. Las Casas was officially appointed Protector of the Indians and spent his life arguing forcefully on their behalf. The New Laws of 1542 were the result, limiting the power of encomenderos, the private holders of grants to indigenous labor previously held in perpetuity. The crown was open to limiting the inheritance of encomiendas in perpetuity as a way to extinguish the coalescence of a group of Spaniards impinging on royal power. In Peru, the attempt of the newly appointed viceroy, Blasco Núñez Vela, to implement the New Laws so soon after the conquest sparked a revolt by conquerors against the viceroy and the viceroy was killed in 1546.  In Mexico, Don Martín Cortés, the son and legal heir of conqueror Hernán Cortés, and other heirs of encomiendas led a failed revolt against the crown. Don Martín was sent into exile, while other conspirators were executed. 
The conquest of the Aztec and Inca empires ended their sovereignty over their respective territorial expanses, replaced by the Spanish Empire. However, the Spanish Empire could not have ruled these vast territories and dense indigenous populations without utilizing the existing indigenous political and economic structures at the local level. A key to this was the cooperation between most indigenous elites with the new ruling structure. The Spanish recognized indigenous elites as nobles and gave them continuing standing in their communities. Indigenous elites could use the noble titles don and doña, were exempt from the head-tax, and could entail their landholdings into cacicazgos.  These elites played an intermediary role between the Spanish rulers and indigenous commoners. Since in central and southern Mexico ( Mesoamerica) and the highland Andes indigenous peoples had existing traditions of payment of tribute and required labor service, the Spanish could tap into these existing to extract wealth. There were few Spaniards and huge indigenous populations, so utilizing indigenous intermediaries was a practical solution to the incorporation of the indigenous population into the new regime of rule. By maintaining hierarchical divisions within communities, indigenous noblemen were the direct interface between the indigenous and Spanish spheres and kept their positions so long as they continued to be loyal to the Spanish crown.     
The exploitation and demographic catastrophe that indigenous peoples experienced from Spanish rule in the Caribbean also occurred as Spaniards expanded their control over territories and their indigenous populations. The crown set the indigenous communities legally apart from Spaniards (as well as Blacks), who comprised the República de Españoles, with the creation of the República de Indios. The crown attempted to curb Spaniards' exploitation, banning Spaniards' bequeathing their private grants of indigenous communities' tribute and encomienda labor in 1542 in the New Laws. In Mexico, the crown established the General Indian Court (Juzgado General de Indios), which heard disputes affecting individual indigenous as well as indigenous communities. Lawyers for these cases were funded by a half-real tax, an early example of legal aid for the poor.  A similar legal apparatus was set up in Lima. 
The Spaniards systematically attempted to transform structures of indigenous governance to those more closely resembling those of Spaniards, so the indigenous city-state became a Spanish town and the indigenous noblemen who ruled became officeholders of the town council (cabildo). Although the structure of the indigenous cabildo looked similar to that of the Spanish institution, its indigenous functionaries continued to follow indigenous practices. In central Mexico, there exist minutes of the sixteenth-century meetings in Nahuatl of the Tlaxcala cabildo.  Indigenous noblemen were particularly important in the early period of colonization, since the economy of the encomienda was initially built on the extraction of tribute and laborfofrom the commoners in their communities. As the colonial economy became more diversified and less dependent on these mechanisms for the accumulation of wealth, the indigenous noblemen became less important for the economy. However, noblemen became defenders of the rights to land and water controlled by their communities. In colonial Mexico, there are petitions to the king about a variety of issues important to particular indigenous communities when the noblemen did not get a favorable response from the local friar or priest or local royal officials.
Works by historians in the twentieth and twenty-first centuries have expanded the understanding of the impact of the Spanish conquest and changes during the more than three hundred years of Spanish rule. There are many such works for Mexico, often drawing on native-language documentation in Nahuatl,   Mixtec,  and Yucatec Maya.   For the Andean area, there are an increasing number of publications as well.   The history of the Guaraní has also been the subject of a recent study. 
In 1524 the Council of the Indies was established, following the system of system of Councils that advised the monarch and made decisions on his behalf about specific matters of government.  Based in Castile, with the assignment of the governance of the Indies, it was thus responsible for drafting legislation, proposing the appointments to the King for civil government as well as ecclesiastical appointments, and pronouncing judicial sentences; as maximum authority in the overseas territories, the Council of the Indies took over both the institutions in the Indies as the defense of the interests of the Crown, the Catholic Church, and of indigenous peoples.  With the 1508 papal grant to the crown of the Patronato real, the crown, rather than the pope, exercised absolute power over the Catholic Church in the Americas and the Philippines, a privilege the crown zealously guarded against erosion or incursion. Crown approval through the Council of the Indies was needed for the establishment of bishoprics, building of churches, appointment of all clerics. 
In 1721, at the beginning of the Bourbon monarchy, the crown transferred the main responsibility for governing the overseas empire from the Council of the Indies to the Ministry of the Navy and the Indies, which were subsequently divided into two separate ministries in 1754. 
The impossibility of the physical presence of the monarch and the necessity of strong royal governance in The Indies resulted in the appointment of viceroys ("vice-kings"), the direct representation of the monarch, in both civil and ecclesiastical spheres. Viceroyalties were the largest territory unit of administration in the civil and religious spheres and the boundaries of civil and ecclesiastical governance coincided by design, to ensure crown control over both bureaucracies.  Until the eighteenth century, there were just two viceroyalties, with the Viceroyalty of New Spain (founded 1535) administering North America, a portion of the Caribbean, and the Philippines, and the viceroyalty of Peru (founded 1542) having jurisdiction over Spanish South America. Viceroys served as the vice-patron of the Catholic Church, including the Inquisition, established in the seats of the viceroyalties (Mexico City and Lima). Viceroys were responsible for good governance of their territories, economic development, and humane treatment of the indigenous populations. 
In the eighteenth-century reforms, the Viceroyalty of Peru was reorganized, splitting off portions to form the Viceroyalty of New Granada (Colombia) (1739) and the Viceroyalty of Rio de la Plata (Argentina) (1776), leaving Peru with jurisdiction over Peru, Charcas, and Chile. Viceroys were of high social standing, almost without exception born in Spain, and served fixed terms.
The Audiencias were initially constituted by the crown as a key administrative institution with royal authority and loyalty to the crown as opposed to conquerors and first settlers.  Although constituted as the highest judicial authority in their territorial jurisdiction, they also had executive and legislative authority, and served as the executive on an interim basis. Judges (oidores) held "formidable power. Their role in judicial affairs and in overseeing the implementation of royal legislation made their decisions important for the communities they served." Since their appointments were for life or the pleasure of the monarch, they had a continuity of power and authority that viceroys and captains-general lacked because of their shorter-term appointments.  They were the "center of the administrative system [and] gave the government of the Indies a strong basis of permanence and continuity." 
Their main function was judicial, as a court of justice of second instance —court of appeal— in penal and civil matters, but also the Audiencias were courts the first instance in the city where it had its headquarters, and also in the cases involving the Royal Treasury.  Besides court of justice, the Audiencias had functions of government as counterweight the authority of the viceroys, since they could communicate with both the Council of the Indies and the king without the requirement of requesting authorization from the viceroy.  This direct correspondence of the Audiencia with the Council of the Indies made it possible for the Council to give the Audiencia direction on general aspects of government. 
Audiencias were a significant base of power and influence for American-born elites, starting in the late sixteenth century, with nearly a quarter of appointees being born in the Indies by 1687. During a financial crisis in the late seventeenth century, the crown began selling Audiencia appointments, and American-born Spaniards held 45% of Audiencia appointments. Although there were restrictions of appointees' ties to local elite society and participation in the local economy, they acquired dispensations from the cash-strapped crown. Audiencia judgments and other functions became more tied to the locality and less to the crown and impartial justice.
During the Bourbon Reforms in the mid-eighteenth century, the crown systematically sought to centralize power in its own hands and diminish that of its overseas possessions, appointing peninsular-born Spaniards to Audiencias. American-born elite men complained bitterly about the change, since they lost access to power that they had enjoyed for nearly a century. 
During the early era and under the Habsburgs, the crown established a regional layer of colonial jurisdiction in the institution of Corregimiento, which was between the Audiencia and town councils. Corregimiento expanded "royal authority from the urban centers into the countryside and over the indigenous population."  As with many colonial institutions, corregimiento had its roots in Castile when the Catholic Monarchs centralize power over municipalities. In the Indies, corregimiento initially functioned to bring control over Spanish settlers who exploited the indigenous populations held in encomienda, in order to protect the shrinking indigenous populations and prevent the formation of an aristocracy of conquerors and powerful settlers. The royal official in charge of a district was the Corregidor, who was appointed by the viceroy, usually for a five-year term. Corregidores collected the tribute from indigenous communities and regulated forced indigenous labor. Alcaldías mayores were larger districts with a royal appointee, the Alcalde mayor.
As the indigenous populations declined, the need for corregimiento decreased and then suppressed, with the alcaldía mayor remaining an institution until it was replaced in the eighteenth-century Bourbon Reforms by royal officials, Intendants. The salary of officials during the Habsburg era were paltry, but the corregidor or alcalde mayor in densely populated areas of indigenous settlement with a valuable product could use his office for personal enrichment. As with many other royal posts, these positions were sold, starting in 1677.  The Bourbon-era intendants were appointed and relatively well paid. 
Spanish settlers sought to live in towns and cities, with governance being accomplished through the town council or Cabildo. The cabildo was composed of the prominent residents (vecinos) of the municipality, so that governance was restricted to a male elite, with majority of the population exercising power. Cities were governed on the same pattern as in Spain and in the Indies the city was the framework of Spanish life. The cities were Spanish and the countryside indigenous.  In areas of previous indigenous empires with settled populations, the crown also melded existing indigenous rule into a Spanish pattern, with the establishment of cabildos and the participation of indigenous elites as officials holding Spanish titles. There were a variable number of councilors (regidores), depending on the size of the town, also two municipal judges (alcaldes menores), who were judges of first instance, and also other officials as police chief, inspector of supplies, court clerk, and a public herald.  They were in charge of distributing land to the neighbors, establishing local taxes, dealing with the public order, inspecting jails and hospitals, preserving the roads and public works such as irrigation ditchs and bridges, supervising the public health, regulating the festive activities, monitoring market prices, or the protection of Indians. 
After the reign of Philip II, the municipal offices, including the councilors, were auctioned to alleviate the need for money of the Crown, even the offices could also be sold, which became hereditary,  so that the government of the cities went on to hands of urban oligarchies.  In order to control the municipal life, the Crown ordered the appointment of corregidores and alcaldes mayores to exert greater political control and judicial functions in minor districts.  Their functions were governing the respective municipalities, administering of justice and being appellate judges in the alcaldes menores' judgments,  but only the corregidor could preside over the cabildo.  However, both charges were also put up for sale freely since the late 16th century. 
Most Spanish settlers came to the Indies as permanent residents, established families and businesses, and sought advancement in the colonial system, such as membership of cabildos, so that they were in the hands of local, American-born (crillo) elites. During the Bourbon era, even when the crown systematically appointed peninsular-born Spaniards to royal posts rather than American-born, the cabildos remained in the hands of local elites. 
As the empire expanded into areas of less dense indigenous populations, the crown created a chain of presidios, military forts or garrisons, that provided Spanish settlers protection from Indian attacks. In Mexico during the sixteenth-century Chichimec War guarded the transit of silver from the mines of Zacatecas to Mexico City. As many as 60 salaried soldiers were garrisoned in presidios.  Presidios had a resident commanders, who set up commercial enterprises of imported merchandise, selling it to soldiers as well as Indian allies. 
The other frontier institution was the religious mission to convert the indigenous populations. Missions were established with royal authority through the Patronato real. The Jesuits were effective missionaries in frontier areas until their expulsion from Spain and its empire in 1767. The Franciscans took over some former Jesuit missions and continued the expansion of areas incorporated into the empire. Although their primary focus was on religious conversion, missionaries served as "diplomatic agents, peace emissaries to hostile tribes ... and they were also expected to hold the line against nomadic nonmissionary Indians as well as other European powers."  On the frontier of empire, Indians were seen as sin razón, ("without reason"); non-Indian populations were described as gente de razón ("people of reason"), who could be mixed-race castas or black and had greater social mobility in frontier regions. 
During the early colonial period, the crown authorized friars of Catholic religious orders ( Franciscans, Dominicans, and Augustinians) to function as priests during the conversion of indigenous populations. During the early Age of Discovery, the diocesan clergy in Spain was poorly educated and considered of a low moral standing, and the Catholic Monarchs were reluctant to allow them to spearhead evangelization. Each order set up networks of parishes in the various regions (provinces), sited in existing indigenous settlements, where Christian churches were built and where evangelization of the indigenous was based. Hernán Cortés requested Franciscan and Dominican friars be sent to New Spain immediately after the conquest of Tenochtitlan to begin evangelization. The Franciscans arrived first in 1525 in a group of twelve, the Twelve Apostles of Mexico. Among this first group was Toribio de Benavente, known now as Motolinia, the Nahuatl word for poor.  
After the 1550s, the crown increasingly favored the diocesan clergy over the religious orders. The diocesan clergy) (also called the [secular clergy]] were under the direct authority of bishops, who were appointed by the crown, through the power granted by the pope in the Patronato Real. Religious orders had their own internal regulations and leadership. The crown had authority to draw the boundaries for dioceses and parishes. The creation of the ecclesiastical hierarchy of the diocesan clergy marked a turning point in the crown's control over the religious sphere. The structure of the hierarchy was in many ways parallel to that of civil governance. The pope was the head of the Catholic Church, but the granting of the Patronato Real to the Spanish monarchy gave the king the power of appointment (patronage) of ecclesiastics. The monarch was head of the civil and religious hierarchies. The capital city of a viceroyalty became of the seat of the archbishop. The region overseen by the archbishop was divided into large units, the diocese, headed by a bishop. The diocese was in turn divided into smaller units, the parish, staffed by a parish priest.
In 1574, Philip II promulgated the Order of Patronage (Ordenaza del Patronato) ordering the religious orders to turn over their parishes to the secular clergy, a policy that secular clerics had long sought for the central areas of empire, with their large indigenous populations. Although implementation was slow and incomplete, it was an assertion of royal power over the clergy and the quality of parish priests improved, since the Ordenanza mandated competitive examination to fill vacant positions.   Religious orders along with the Jesuits then embarked on further evangelization in frontier regions of the empire.
The Jesuits resisted crown control, refusing to pay the tithe on their estates that supported the ecclesiastical hierarchy and came into conflict with bishops. The most prominent example is in Puebla, Mexico, when Bishop Juan de Palafox y Mendoza was driven from his bishopric by the Jesuits. The bishop challenged the Jesuits' continuing to hold Indian parishes and function as priests without the required royal licenses. His fall from power is viewed as an example of the weakening of the crown in the mid-seventeenth century since it failed to protect their duly appointed bishop.  The crown expelled the Jesuits from Spain and The Indies in 1767 during the Bourbon Reforms.
Inquisitional powers were initially vested in bishops, who could root out idolatry and heresy. In Mexico, Bishop Juan de Zumárraga prosecuted and had executed in 1539 a Nahua lord, known as Don Carlos of Texcoco for apostasy and sedition for having converted to Christianity and then renounced his conversion and urged others to do so as well. Zumárraga was reprimanded for his actions as exceeding his authority.   When the formal institution of the Inquisition was established in 1571, indigenous peoples were excluded from its jurisdiction on the grounds that they were neophytes, new converts, and not capable of understanding religious doctrine.
It has been estimated that over 1.86 million Spaniards emigrated to Latin America in the period between 1492 and 1824, with millions more continuing to immigrate following independence. 
Native populations declined significantly during the period of Spanish expansion. In Hispaniola, the indigenous Taíno pre-contact population before the arrival of Columbus of several hundred thousand had declined to sixty thousand by 1509. The population of the Native American population in Mexico declined by an estimated 90% (reduced to 1–2.5 million people) by the early 17th century.[ citation needed] In Peru, the indigenous Amerindian pre-contact population of around 6.5 million declined to 1 million by the early 17th century.[ citation needed] The overwhelming cause of the decline in both Mexico and Peru was infectious diseases, such as smallpox and measles,  although the brutality of the Encomienda also played a significant part in the population decline.[ citation needed]
Of the history of the indigenous population of California, Sherburne F. Cook (1896–1974) was the most painstakingly careful researcher. From decades of research, he made estimates for the pre-contact population and the history of demographic decline during the Spanish and post-Spanish periods. According to Cook, the indigenous Californian population at first contact, in 1769, was about 310,000 and had dropped to 25,000 by 1910. The vast majority of the decline happened after the Spanish period, during the Mexican and US periods of Californian history (1821–1910), with the most dramatic collapse (200,000 to 25,000) occurring in the US period (1846–1910).   
The largest population in Spanish America was and remained indigenous, what Spaniards called "Indians" (indios), a category that did not exist before the arrival of the Europeans. The crown separated them into the República de Indios. Europeans immigrated from various parts of Spain, and also initially more men than women. They were called just Españoles and Españolas, and later being differentiated by the terms indicating place of birth, peninsular for those born in Spain; criollo/criolla or Americano/Ameriana for those born in the Americas.
Spaniards brought African slaves to the Americas as early as the conquest. They were classified as part of the República de Españoles, since culturally they were part of the Spanish sphere. In urban areas, many Africans (negros) were able to achieve their freedom, so that a large free Black and Mulatto (Black + European) population emerged. Europeans and Indigenous parents produced Mestizo offspring, who were also part of the República de Españoles. Raced race individuals, those with complex ancestries, were classified as castas.
In areas of dense, stratified indigenous populations, especially Mesoamerica and the Andean region, Spanish conquerors awarded perpetual private grants of labor and tribute particular indigenous settlements, in encomienda were in a privileged position to accumulate private wealth. Spaniards had some knowledge of the existing indigenous practices of labor and tribute, so that learning in more detail what tribute particular regions delivered to the Aztec empire prompted the creation of Codex Mendoza, a codification for Spanish use. The rural regions remained highly indigenous, with little interface between the large numbers of indigenous and the small numbers of the República de Españoles, which included Blacks and mixed-race castas. Tribute goods in Mexico were most usually lengths of cotton cloth, woven by women, and maize and other foodstuffs produced by men. These could be sold in markets and thereby converted to cash. In the early period for Spaniards, formal ownership of land was less important than control of indigenous labor and receiving tribute. Spaniards had seen the disappearance of the indigenous populations in the Caribbean, and with that, the disappearance of their main source of wealth, propelling Spaniards to expand their regions of control. With the conquests of the Aztec and Inca empires, large numbers of Spaniards emigrated from the Iberian peninsula to seek their fortune or to pursue better economic conditions for themselves. The establishment of large, permanent Spanish settlements attracted a whole range of new residents, who set up shop as carpenters, bakers, tailors and other artisan activities.
The early Caribbean proved a massive disappointment for Spaniards, who had hoped to find mineral wealth and exploitable indigenous populations. Gold existed in only small amounts, and the indigenous peoples died off in massive numbers. For the colony's continued existence, a reliable source of labor was needed. That was of enslaved Africans. Cane sugar imported from the Old World was the high value, low bulk export product that became the bulwark of tropical economies of the Caribbean islands and coastal Tierra Firme (the Spanish Main), as well as Portuguese Brazil.
Silver was the bonanza the Spaniards sought. Large deposits were found in a single mountain in the viceroyalty of Peru, the Cerro Rico, in what is now Bolivia, and in several places outside of the dense indigenous zone of settlement in northern Mexico, Zacatecas and Guanajuato.  In the Andes, Viceroy Francisco de Toledo revived the indigenous rotary labor system of the mita to supply labor for silver mining.    In Mexico, the labor force had to be lured from elsewhere in the colony, and was not based on traditional systems of rotary labor. In Mexico, refining took place in haciendas de minas, where silver ore was refined into pure silver by amalgamation with mercury in what was known as the patio process. Ore was crushed with the aid of mules and then mercury could be applied to draw out the pure silver. Mercury was a monopoly of the crown. In Peru, the Cerro Rico's ore was processed from the local mercury mine of Huancavelica, while in Mexico mercury was imported from the Almadén mercury mine in Spain. Mercury is a neurotoxin, which damaged and killed human and mules coming into contact with it. In the Huancavelica region, mercury continues to wreak ecological damage.   
To feed urban populations and mining work forces, small-scale farms (ranchos), ( estancias), and large-scale enterprises ( haciendas) emerged to fill the demand, especially for foodstuffs that Spaniards wanted to eat, most especially wheat. In areas of sparse population, ranching of cattle (ganado mayor) and smaller livestock (ganado menor) such as sheep and goats ranged widely and were largely feral. There is debate about the impact of ranching on the environment in the colonial era, with sheep herding being called out for its negative impact, while other contest that.  With only a small labor force to draw on, ranching was an ideal economic activity for some regions. Most agriculture and ranching supplied local needs, since transportation was difficult, slow, and expensive.  Only the most valuable low bulk products would be exported.
Cacao beans for chocolate emerged as an export product as Europeans developed a taste for sweetened chocolate. Another major export product was cochineal, a color-fast red dye made from dried bugs living on cacti. Also cochineal is technically an animal product, the insects were placed on cacti and harvested by the hands of indigenous laborers. It became the second-most important export product from Spanish America after silver.
During the Napoleonic Peninsular War in Europe between France and Spain, assemblies called juntas were established to rule in the name of Ferdinand VII of Spain. The Libertadores (Spanish and Portuguese for "Liberators") were the principal leaders of the Spanish American wars of independence. They were predominantly criollos (Americas-born people of European ancestry, mostly Spanish or Portuguese), bourgeois and influenced by liberalism and in some cases with military training in the mother country.
In 1809 the first declarations of independence from Spanish rule occurred in the Viceroyalty of Peru. The first two were in the Alto Perú, present-day Bolivia, at Charcas (present day Sucre, May 25), and La Paz (July 16); and the third in present-day Ecuador at Quito (August 10). In 1810 Mexico declared independence, with the Mexican War of Independence following for over a decade. In 1821 Treaty of Córdoba established Mexican independence from Spain and concluded the War. The Plan of Iguala was part of the peace treaty to establish a constitutional foundation for an independent Mexico.
These began a movement for colonial independence that spread to Spain's other colonies in the Americas. The ideas from the French and the American Revolution influenced the efforts. All of the colonies, except Cuba and Puerto Rico, attained independence by the 1820s. The British Empire offered support, wanting to end the Spanish monopoly on trade with its colonies in the Americas.
In 1898, the United States achieved victory in the Spanish–American War with Spain, ending the Spanish colonial era. Spanish possession and rule of its remaining colonies in the Americas ended in that year with its sovereignty transferred to the United States. The United States took occupation of Cuba, the Philippines, and Puerto Rico. Puerto Rico continues to be a possession of the United States, now officially continues as a self-governing unincorporated territory.
In the twentieth century, there have been a number of films depicting the life of Christopher Columbus. One in 1949 stars Frederic March as Columbus.  With the 1992 commemoration (and critique) of Columbus, more cinematic and television depictions of the era appeared, including a TV miniseries with Gabriel Byrne as Columbus.  Christopher Columbus: The Discovery (1992) has Georges Corroface as Columbus with Marlon Brando as Tomás de Torquemada and Tom Selleck as King Ferdinand and Rachel Ward as Queen Isabela.  1492: The Conquest of Paradise stars Gerard Depardieu as Columbus and Sigorney Weaver as Queen Isabel.  A 2010 film, Even the Rain starring Gael García Bernal, is set in modern Cochabamba, Bolivia during the Cochabamba Water War, following a film crew shooting a controversial life of Columbus.  A 1995 Bolivian-made film is in some ways similar to Even the Rain is To Hear the Birds Singing, with a modern film crew going to an indigenous settlement to shot a film about the Spanish conquest and end up replicating aspects of the conquest. 
For the conquest of Mexico, a 2019 an eight-episode Mexican TV miniseries Hernán depicts the conquest of Mexico. Other notable historical figures in the production are Malinche, Cortés cultural translator, and other conquerors Pedro de Alvarado, Cristóbal de Olid, Bernal Díaz del Castillo. Showing the indigenous sides are Xicotencatl, a leader of the Spaniards' Tlaxcalan allies, and Aztec emperors Moctezuma II and Cuitlahuac.  The story of Doña Marina, also known as Malinche, was the subject of a Mexican TV miniseries in 2018.  A major production in Mexico was the 1998 film, The Other Conquest, which focuses on a Nahua in the post-conquest era and the evangelization of central Mexico. 
The epic journey of Álvar Núñez Cabeza de Vaca has been portrayed in a 1991 feature-length Mexican film, Cabeza de Vaca.  The similarly epic and dark journey of Lope de Aguirre was made into a film by Werner Herzog, Aguirre, the Wrath of God (1972), starring Klaus Kinsky. 
The Mission was a 1996 film idealizing a Jesuit mission to the Guaraní in the territory disputed between Spain and Portugal. The film starred Robert De Niro, Jeremy Irons, and Liam Neeson and It won an Academy Award. 
The life of seventeenth-century Mexican nun, Sor Juana Inés de la Cruz, renowned in her lifetime, has been portrayed in a 1990 Argentine film, I, the Worst of All  and in a TV miniseries Juana Inés.  Seventeenth-century Mexican trickster, Martín Garatuza was the subject of a late nineteenth-century novel by Mexican politician and writer, Vicente Riva Palacio. In the twentieth century, Garatuza's life was the subject of a 1935 film  and a 1986 telenovela, Martín Garatuza. 
For the independence era, the 2016 Bolivian-made film made about Mestiza independence leader Juana Azurduy de Padilla is part of the recent recognition of her role in the independence of Argentina and Bolivia. 
- Viceroyalty of New Spain (1535–1821)
- Captaincy General of the Philippines (administered by New Spain from 1565 to 1821, then after Mexican independence transferred to and directly administered by Madrid until 1898)
- Captaincy General of Cuba (until 1898) – Florida was Included in this captaincy general until 1819.
- Captaincy General of Puerto Rico (until 1898)
- Santo Domingo (last Spanish rule 1861–1865)
- Viceroyalty of Perú (1542–1824)
- Captaincy General of Chile (1541–1818)
- Viceroyalty of New Granada (1717–1819)
- Captaincy General of Venezuela
- Viceroyalty of the Río de la Plata (1776–1814)
- Atlantic World
- Cartography of Latin America
- Spanish Empire
- Spanish American Enlightenment
- Black legend (Spain)
- Hapsburg Spain
- List of largest empires
- Population history of indigenous peoples of the Americas
- Timeline of imperialism § Colonization of North America
- Valladolid debate
- Viceroyalty of New Spain
- Viceroyalty of Peru
- MacIas, Rosario Marquez; MacÍas, Rosario Márquez (1995). La emigración española a América, 1765–1824. ISBN 9788474688566
- "La catastrophe démographique" (The Demographic Catastrophe) in L'Histoire n°322, July–August 2007, p. 17
- Forsythe, David P. (2009). Encyclopedia of Human Rights. Volume 4. Oxford University Press. p. 297. ISBN 978-0195334029.CS1 maint: ref=harv ( link)
- Ida Altman, S.L. Cline, and Javier Pescador, The Early History of Greater Mexico, Pearson, 2003 pp. 27–28.
- Cook, David Noble. "Treaty of Tordesillas (1494)" in Encyclopedia of Latin American History and Culture. Vol. 5, p. 253
- Muldoon, James. "Papal Responsibility for the Infidel: Another Look at Alexander VI's" Inter Caetera"." The Catholic Historical Review 64.2 (1978): 168-184.
- Ida Altman et al., The Early History of Greater Mexico, pp. 35–36.
- Lockhart, James and Stuart B. Schwartz, Early Latin America. New York: Cambridge University Press 1982, pp. 78–79.
- Restall, Matthew, Seven Myths of the Spanish Conquest. New York: Oxford University Press 2003.
- Altman, Ida and David Wheat, eds. The Spanish Caribbean and the Atlantic World in the Long Sixteenth Century. Lincoln: University of Nebraska Press 2019. ISBN 978-0803299573
- Maltby, William B. "The Black Legend" in Encyclopedia of Latin American History and Culture vol. 1 pp. 346–348.|New York: Charles Scribner's Sons 1996}}
- "Archived copy" (PDF). Archived from the original (PDF) on 2009-03-20. Retrieved 2014-03-05.CS1 maint: archived copy as title ( link) Sucre State Government: Cumaná in History (Spanish)
- Tibesar, A.S. (1957). "The Franciscan Province of the Holy Cross of Espanañola, 1505–1559". The Americas. 13 (4): 377–389. doi: 10.2307/979442. JSTOR 979442.
- Sauer, Carl O. The Early Spanish Main. Berkeley and Los Angeles: University of California Press 1966.
- Altman, The Early History of Greater Mexico, pp.53-54.
- León-Portilla, Miguel. The Broken Spears. Boston, Beacon Press 2006 ISBN 978-0807055007
- Lockhart, James. We People Here: Nahuatl Accounts of The Conquest of Mexico. Repertorium Columbianum 2004. ISBN 978-1592446810
- Schwartz, Stuart B. Victors and Vanquished: Spanish and Nahua Views of the Fall of the Mexica Empire. Bedford/St Martin’s 2017. ISBN 978-1319094850
- Lockhart and Schwartz, Early Latin America, pp. 80-85.
- Restall, Seven Myths of the Spanish Conquest
- Robert S. Chamberlain, The Conquest and Colonization of Yucatan. Washington DC: Carnegie Institution.
- Warren, J. Benedict. The Conquest of Michoacán: The Spanish Domination of the Tarascan Kingdom in Western Mexico, 1521–1530. Norman: University of Oklahoma Press|1985
- Altman, Ida. The War for Mexico's West. Albuquerque: University of New Mexico Press 2010.
- Philip W. Powell, Soldiers, Indians, and Silver: North America's Last Frontier War. Tempe: Center for Latin America Studies, Arizona State University 1975. First published by University of California Press 1952.
- Collier, Simon. "Chile: Colonial Foundations" in Encyclopedia of Latin American History and Culture, vol. 2, p. 99.
- Clements Markham, The Conquest of New Granada (1912) online
- Avellaneda Navas, José Ignacio. The Conquerors of the New Kingdom of Granada (Albuquerque: University of New Mexico Press, 1995) ISBN 978-0-8263-1612-7
- Miller, Gary. “Venezuela: The Colonial Era” in ‘’Encyclopedia of Latin American History and Culture. Vol. 5, pp. 378-79.
- Dressing, J. David. “House of Welser” in Encyclopedia of Latin American History and Culture, vol. 5, p. 453.
- Cushner, Nicolas P. “Argentina: The Colonial Period” in Encyclopedia of Latin American History and Culture, vol. 1, pp. 142-43.
- Lockhart and Schwartz, Early Latin America, pp. 84-85.
- Lockhart and Schwartz, Early Latin America pp. 84-85.
- Keen, Benjamin and Keith Haynes. A History of Latin America. 9th edition. Boston: Wadsworth 2013 pp. 76-78
- Cabeza de Vaca, Álvar Núñez. The Narrative of Cabeza De Vaca, Translation of La Relacion, ed. Rolena Adorno and Patrick Charles Pautz. Lincoln, NE: University of Nebraska Press 2003. ISBN 0-8032-6416-X
- Carte, Rebecca A. Capturing the Landscape of New Spain: Baltasar Obregón and the 1564 Ibarra Expedition. Tucson: University of Arizona Press 2015.
- Simmons, Marc, The Last Conquistador: Juan de Oñate and the Settling of the Far Southwest, University of Oklahoma Press, Norman, 1991 pp. 193–94
- Writer, Amanda Martinez. "Oñate statue taken down, for now". Taos News. Retrieved 2020-06-17.
- Lockhart and Schwartz, Early Latin America, p.89.
- Lockhart and Schwartz, Early Latin America, pp. 87-88
- Crosby, Alfred W., The Columbian Exchange: Biological and Cultural Consequences of 1492. Greenwood Press 1973.
- Crosby, Alfred W. Ecological Imperialism: The Biological Expansion of Europe, 900–1900. 2nd edition. New York: Cambridge University Press 2015. ISBN 978-1107569874
- Cook, Noble David. Born to Die: Disease and New World Conquest, 1492-1650. New York: Cambridge University Press 2010. ISBN 978-0521627306
- Powell, Philip Wayne. Soldiers, Indians, Silver. Berkeley and Los Angeles: University of Calforonia Press 1969.
- Melville, Elinor G.K. A Plague of Sheep: Environmental Consequences of the Conquest of Mexico. New York: Cambridge University Press 1994.
- Parry, J.H. (1953). The Sale of Public Office in the Spanish Indies Under the Habsburgs. Ibero-Americana 37. University of California Press. p. 4.
- Brading 1971, pp. 33-94. sfn error: no target: CITEREFBrading1971 ( help)
- Kuethe, Allan J. "The Bourbon Reforms" in Encyclopedia of Latin American History and Culture 1996, vol. 1, p. 399-401 harvnb error: no target: CITEREFEncyclopedia_of_Latin_American_History_and_Culture1996 ( help)
- Nader, Helen, "Antonio de Fonseca" in Bedini 1992, pp. 282–283 harvnb error: no target: CITEREFBedini1992 ( help)
- Cook, Noble David. "Nicolás de Ovando" in Encyclopedia of Latin American History and Culture 1996, vol. 4, p. 254 harvnb error: no target: CITEREFEncyclopedia_of_Latin_American_History_and_Culture1996 ( help)
- Delamarre-Sallard, Catherine (2008). Manuel de civilisation espagnole et latino-américaine (in Spanish). Editions Bréal. p. 130. ISBN 978-2-7495-0335-6.
- Sanz Ayán, Carmen (1993). Sevilla y el comercio de Indias (in Spanish). Ediciones Akal. p. 23. ISBN 978-84-460-0214-7.
- Andreo García, Juan (2007). "Su Majestad quiere gobernar: la Administración española en Indias durante los siglos XVI y XVII". In Bautista Vilar, Juan; Peñafiel Ramón, Antonio; Irigoyen López, Antonio (eds.). Historia y sociabilidad: homenaje a la profesora María del Carmen Melendreras Gimeno (in Spanish). EDITUM. p. 279. ISBN 978-84-8371-654-0.
- Góngora 1998, p. 99. sfn error: no target: CITEREFGóngora1998 ( help)
- Lagos Carmona 1985, p. 119. sfn error: no target: CITEREFLagos_Carmona1985 ( help)
- Lagos Carmona 1985, p. 122. sfn error: no target: CITEREFLagos_Carmona1985 ( help)
- Historia general de España 1992, p. 601. sfn error: no target: CITEREFHistoria_general_de_España1992 ( help)
- Góngora 1998, p. 97. sfn error: no target: CITEREFGóngora1998 ( help)
- Muro Romero, Fernando (1975). Las presidencias-gobernaciones en Indias (siglo XVI) (in Spanish). CSIC. p. 177. ISBN 978-84-00-04233-2.
- Malberti de López, Susana (2006). "Las instituciones políticas en la región de Cuyo". In Instituto de Historia Regional y Argentina "Héctor Domingo Arias" (ed.). Desde San Juan hacia la historia de la región (in Spanish). effha. p. 141. ISBN 978-950-605-481-6.
- Bushnell, Amy (1981). The King's Coffer: Proprietors of the Spanish Florida Treasury 1565-1702. Gainesville, Florida: University Presses of Florida. pp. 1–2. ISBN 0-8130-0690-2. Retrieved May 23, 2019.
- Bushnell 1981, pp. 1–2; Chipman 2005 harvnb error: no target: CITEREFChipman2005 ( help)
- Bushnell 1981, p. 1–2; Chipman 2005 sfnm error: no target: CITEREFChipman2005 ( help).
- "1512–1513: Laws of Burgos", Colonial Latin America, Peter Bakewell, 1998, retrieved 2008-10-08
- Esparza, José Javier (2015). La cruzada del océano: La gran aventura de la conquista de América (in Spanish). La Esfera de los Libros. ISBN 9788490602638.
- Scott, James Brown (2000). The Spanish origin of international law (4th ed.). Union, NJ: Lawbook Exchange. ISBN 978-1-58477-110-4.
- Dumont, Jean (1997). El amanecer de los derechos del hombre : la controversia de Valladolid (in Spanish). Madrid: Encuentro. ISBN 978-8474904154.
- Cook, Noble David. "Blasco Núñez Vela" in Encyclopedia of Latin American History and Culture, vol. 4, p. 204.
- Warren, J. Benedict."Questionnaires from the Trial of the Second Marqués del Valle for Conspiracy, 1566" in The Harkness Collection in the Library of Congress: Manuscripts concerning Mexico, a guide. Washington, D.C. 1974.
- Fernández de Recas, Guillermo S. Cacicazgos y nobiliario indígena de la Nueva España. Instituto Bibliográfico Mexicano 1961
- Gibson, Charles. ‘’The Aztecs under Spanish Rule. Stanford: Stanford University Press 1964
- Lockhart, James. The Nahuas after the Conquest. Stanford: Stanford University Press 1992.
- Rowe, John. “The Incas Under Spanish Colonial Institutions”. Hispanic American Historical Review, vol. 37 (2) May 1957
- Spalding, Karen. "Social climbers: Changing patterns of mobility among the Indians of colonial Peru." Hispanic American Historical Review 50.4 (1970): 645-664.
- Spalding, Karen. "Kurakas and commerce: a chapter in the evolution of Andean society." Hispanic American Historical Review 53.4 (1973): 581-599.
- Borah, Woodrow. Justice by Insurance: The General Indian Court of Colonial Mexico and the Legal Aides of the Half-Real. Berkeley and Los Angeles: University of California Press 1983. ISBN 978-0520048454
- Borah, Woodrow. "Juzgado General de Indios del Perú o Juzgado Particular de Indios de el cercado de Lima." Revista chilena de historia del derecho 6 (1970
- The Tlaxcalan Actas: A Compendium of the Records of the Cabildo of Tlaxcala (1545-1627) James Lockhart, Frances Berdan, and Arthur J.O. Anderson. 1986. University of Utah Press 1986. ISBN 978-0874802535
- Gibson, Charles. The Aztecs Under Spanish Rule. Stanford: Stanford University Press 1964.
- Lockhart, James. The Nahuas After the Conquest. Stanford University Press 1992.
- Terraciano, Kevin. The Mixtecs of colonial Oaxaca: Ñudzahui history, sixteenth through eighteenth centuries. Stanford University Press, 2004.
- Farriss, Nancy Marguerite. Maya society under colonial rule: The collective enterprise of survival. Princeton University Press, 1984.
- Restall, Matthew. The Maya world: Yucatec culture and society, 1550-1850. Stanford University Press, 1999.
- Stern, Steve. Peru's Inidan Peoples and the Challenge of Conquest: Huamanga to 1640. 2nd edition. Madison: University of Wisconsin Press 1992.
- Andrien, Kenneth J. Andean World: Indigenous History, Culture, and Consciousness under Spanish Rule, 1532-1825. Albuquerque: University of New Mexico Press 2001.
- Ganson, Barbara. The Guaraní Under Spanish Rule in Río de la Plata. Stanford: Stanford University 2003.
- Cano, José (2007). "El gobierno y la imagen de la Monarquía Hispánica en los viajeros de los siglos XVI y XVII. De Austrias a Borbones". La monarquía de España y sus visitantes: siglos XVI al XIX Colaborador Consuelo Maqueda Abreu (in Spanish). Editorial Dykinson. pp. 21–22. ISBN 9788498491074.
- Jiménez Núñez, Alfredo (2006). El gran norte de México: una frontera imperial en la Nueva España (1540–1820) (in Spanish). Editorial Tebar. p. 41. ISBN 978-84-7360-221-1.
- Mecham 1966, p. 111-137. sfn error: no target: CITEREFMecham1966 ( help)
- Mecham 1966, p. 26. sfn error: no target: CITEREFMecham1966 ( help)
- Burkholder, Mark A. "Viceroyalty, Viceroy" in Encyclopedia of Latin American History and Culture 1996, vol. 5, p. 408-409 harvnb error: no target: CITEREFEncyclopedia_of_Latin_American_History_and_Culture1996 ( help)
- Góngora 1998, p. 100. sfn error: no target: CITEREFGóngora1998 ( help)
- Burkholder, "Audiencia" in Encyclopedia of Latin American History and Culture 1996, vol. 1, p. 235-236 harvnb error: no target: CITEREFEncyclopedia_of_Latin_American_History_and_Culture1996 ( help)
- Fernando Cervantes, "Audiencias" in Encyclopedia of Mexico. Chicago: Fitzroy Dearborn 1997, p. 109.
- Garavaglia, Juan Carlos; Marchena Fernández, Juan (2005). América Latina de los orígenes a la Independencia (in Spanish). Editorial Critica. p. 266. ISBN 978-84-8432-652-6.
- Burkholder, Mark A. "Corregidor" in Encyclopedia of Latin and mexicpo is the best History and Culture 1996, vol. 2, p. 272 harvnb error: no target: CITEREFEncyclopedia_of_Latin_and_mexicpo_is_the_best_History_and_Culture1996 ( help)
- Brungardt, Maurice (2006). "Corregidor/Corregimiento". Iberia and the Americas: culture, politics, and history. 1. Santa Barbara: ABC Clio. pp. 361–363.
- Lockhart & Schwartz 1983, p. 66-67. sfn error: no target: CITEREFLockhartSchwartz1983 ( help)
- Bennassar 2001, p. 98. sfn error: no target: CITEREFBennassar2001 ( help)
- Delgado de Cantú, Gloria M. (2005). El mundo moderno y contemporáneo (in Spanish). 1. Pearson Educación. p. 90. ISBN 978-970-26-0665-9.
- Bennassar 2001, p. 99. sfn error: no target: CITEREFBennassar2001 ( help)
- Orduña Rebollo, Enrique (2003). Municipios y provincias: Historia de la Organización Territorial Española (in Spanish). INAP. p. 237. ISBN 978-84-259-1249-8.
- Historia general de España 1992, p. 615. sfn error: no target: CITEREFHistoria_general_de_España1992 ( help)
- Pérez Guartambel, Carlos (2006). Justicia indígena (in Spanish). Universidad de Cuenca. pp. 49–50. ISBN 978-9978-14-119-9.
- Bosco Amores, Juan (2006). Historia de América (in Spanish). Editorial Ariel. p. 273. ISBN 978-84-344-5211-4.
- Bennassar 2001, p. 101. sfn error: no target: CITEREFBennassar2001 ( help)
- Lockhart & Schwartz 1983, p. 322. sfn error: no target: CITEREFLockhartSchwartz1983 ( help)
- Gibson 1966, p. 191-192. sfn error: no target: CITEREFGibson1966 ( help)
- Altman, Cline & Javier Pescador 2003, pp. 321-322. sfn error: no target: CITEREFAltmanClineJavier_Pescador2003 ( help)
- Ramírez, Susan E. "Missions: Spanish America" in Encyclopedia of Latin American History and Culture 1996, vol. 4, p. 77 harvnb error: no target: CITEREFEncyclopedia_of_Latin_American_History_and_Culture1996 ( help)
- Miranda, Gloria E. (1988). "Racial and Cultural Dimensions of "Gente de Razón" Status in Spanish and Mexican California". Southern California Quarterly. 70 (3): 265–278. doi: 10.2307/41171310. JSTOR 41171310.
- Ricard, Robert (1966). The Spiritual Conquest of Mexico. Berkeley: University of California Press.
- Toribio de Benavente Motolinia, Motolinia's History of the Indians of New Spain. Translated by Elizabeth Andros Foster. Greenwood Press 1973
- Padden, Robert C. (1956). "The Ordenanza del Patronazgo of 1574". The Americas (12): 333–354.
- Schwaller, John F (1986). "The Ordenanza del Patronazgo in New Spain, 1574–1600". The Americas (42): 253–274.
- Brading 1993, pp. 241-247. sfn error: no target: CITEREFBrading1993 ( help)
- Don, Patricia Lopes. "The 1539 inquisition and trial of Don Carlos of Texcoco in early Mexico." Hispanic American Historical Review 88, no. 4 (2008): 573-606.
- Castaño, Victoria Ríos. "Not a Man of Contradiction: Zumárraga as Protector and Inquisitor of the Indigenous People of Central Mexico." Hispanic Research Journal 13, no. 1 (2012): 26-40.
- MacIas, Rosario Marquez; MacÍas, Rosario Márquez (1995). La emigración española a América, 1765–1824. ISBN 9788474688566.
- "The Story Of... Smallpox". Pbs.org. Retrieved 2019-03-02.
- Baumhoff, Martin A. 1963. Ecological Determinants of Aboriginal California Populations. University of California Publications in American Archaeology and Ethnology 49:155–236.
- Powers, Stephen. 1875. "California Indian Characteristics". Overland Monthly 14:297–309. on-line
- Cook's judgement on the effects of U.S rule upon the native Californians is harsh: "The first (factor) was the food supply... The second factor was disease. ...A third factor, which strongly intensified the effect of the other two, was the social and physical disruption visited upon the Indian. He was driven from his home by the thousands, starved, beaten, raped, and murdered with impunity. He was not only given no assistance in the struggle against foreign diseases, but was prevented from adopting even the most elementary measures to secure his food, clothing, and shelter. The utter devastation caused by the white man was literally incredible, and not until the population figures are examined does the extent of the havoc become evident."Cook, Sherburne F. 1976b. The Population of the California Indians, 1769–1970. University of California Press, Berkeley|p. 200
- Brading, D.A. and Harry Cross, “Colonial Silver Mining: Mexico and Peru.” Hispanic America Historical Review 52 (1972): 545-579.
- Bakewell, Peter J. Miners of the Red Mountain: Indian Labor in Potosí, 1545-1650. Albuquerque: University of New Mexico Press 1984.
- Cole, Jeffrey A., The Potosí Mita, 1573-1700: Compulsory Labor in the Andes, Stanford: Stanford University Press 1985.
- Tandeter, Enrique, Coercion and Market: Silver Mining in Colonial Potosí, 1692-1826. Albuquerque: University of New Mexico Press 1993.
- Whitaker, Arthur P.The Huancavelica Mercury Mine: A Contribution to the History of the Bourbon Renaissance in the Spanish Empire. Cambridge: Harvard University Press 1941.
- Brown, Kendall W., "The Spanish Imperial Mercury Trade and the American Mining Expansion Under the Bourbon Monarchy," in The Political Economy of Spanish America in the Age of Revolution, ed. Kenneth J. Andrien and Lyman L. Johnson. Albuquerque: University of New Mexico Press 1994, pp. 137-68.
- Robins, Nicholas A., Mercury Mining and Empire: The Human and Ecological Cost of Colonial Silver Mining in the Andes. Bloomington: Indiana University Press 2011.
- Van Ausdal, Shawn, and Robert W. Wilcox. "Hoofprints: Cattle Ranching and Landscape Transformation" in A Living Past: Environmental Histories of Modern Latin America, eds. John Soluri, Claudia Leal, and José Augusto Pádua. New York: Berghahn 2019, pp. 183-84
- Van Young, Eric. Hacienda and Market in Eighteenth-Century Mexico: The Rural Economy of the Guadalajara Region, 1675–1820. Berkeley: University of California Press 1981.
-  Columbus
-  Christopher Columbus TV miniseries
- Christopher Columbus: The Discovery.
-  1492: The Conquest of Paradise.
-  Even the Rain
-  To Hear the Birds Singing
-  Hernán
-  Malinche
-  The Other Conquest
-  Cabeza de Vaca
-  Aguirre, the Wrath of God.
-  The Mission.
-  I, the Worst of All
-  Juana Inés
-  Martín Garatuza
-  Martín Garatuza
-  Juana Azurduy: Guerrillera de la Patria Grande
- Altman, Ida and David Wheat, eds. The Spanish Caribbean and the Atlantic World in the Long Sixteenth Century. Lincoln: University of Nebraska Press 2019. ISBN 978-0803299573
- Brading, D. A., The First America: the Spanish Monarchy, Creole Patriots, and the Liberal State, 1492–1867 (Cambridge: Cambridge University Press, 1993).
- Burkholder, Mark A. and Lyman L. Johnson. Colonial Latin America, 10th ed. Oxford University Press 2018. ISBN 978-0190642402
- Chipman, Donald E. and Joseph, Harriett Denise. Spanish Texas, 1519–1821. (Austin: University of Texas Press, 1992)
- Clark, Larry R. Imperial Spain’s Failure to Colonize Southeast North America: 1513 - 1587 (TimeSpan Press 2017) updated edition to Spanish Attempts to Colonize Southeast North America (McFarland Publishing, 2010)
- Elliott, J. H. Empires of the Atlantic World: Britain and Spain in America, 1492–1830 (New Haven: Yale University Press, 2007)
- Gibson, Carrie. Empire's Crossroads: A History of the Caribbean from Columbus to the Present Day (New York: Grove Press, 2015)
- Gibson, Carrie. El Norte: The Epic and Forgotten Story of Hispanic North America (New York: Atlantic Monthly Press, 2019)
- Gibson, Charles. Spain in America. New York: Harper and Row 1966. ISBN 978-1299360297
- Goodwin, Robert. América: The Epic Story of Spanish North America, 1493-1898 (London: Bloomsbury Publishing, 2019)
- Hanke, Lewis. The Spanish Struggle for Justice in the Conquest of America (Boston: Little, Brown, and Co., 1965).
- Haring, Clarence H. The Spanish Empire in America (London: Oxford University Press, 1947)
- Kamen, Henry. Empire: How Spain Became a World Power, 1492–1763 (HarperCollins, 2004)
- Lockhart, James and Stuart B. Schwartz. Early Latin America: A History of Colonial Spanish America and Brazil. New York: Cambridge University Press 1983. ISBN 978-0521299299
- Merriman, Roger Bigelow. The Rise of the Spanish Empire in the Old World and in the New (4 Vol. London: Macmillan, 1918) online free
- Portuondo, María M. Secret Science: Spanish Cosmography and the New World (Chicago: Chicago UP, 2009).
- Restall, Matthew and Fernández-Armesto, Felipe. The Conquistadors: A Very Short Introduction (2012) excerpt and text search
- Restall, Matthew and Kris Lane. Latin America in Colonial Times. New York: Cambridge University Press 2011.
- Thomas, Hugh. Rivers of Gold: the rise of the Spanish Empire, from Columbus to Magellan (2005)
- Weber, David J. The Spanish Frontier in North America (Yale University Press, 1992)
- Cañeque, Alejandro "The Political and Institutional History of Colonial Spanish America" History Compass (April 2013) 114 pp 280–291, doi: 10.1111/hic3.12043
- Herzog, Tamar (2018). " Indigenous Reducciones and Spanish Resettlement: Placing Colonial and European History in Dialogue". Ler Historia (72): 9-30. doi:10.4000/lerhistoria.3146. ISSN 0870-6182.
- Weber, David J. "John Francis Bannon and the Historiography of the Spanish Borderlands: Retrospect and Prospect." Journal of the Southwest (1987): 331–363. See John Francis Bannon
- Weber, David J. “The Spanish Borderlands, Historiography Redux.” The History Teacher, vol. 39, no. 1, 2005, pp. 43–56. JSTOR, online.
|Wikiquote has quotations related to: Spanish colonization of the Americas|
- Spanish Exploration and Conquest of North America
- Spain in America (Edward Gaylord Bourne, 1904) 'Spain in America'
- The Spanish Borderlands (Herbert E. Bolton, 1921) 'The Spanish Borderlands'
- Indigenous Puerto Rico DNA evidence upsets established history
- The short film Spanish Empire in the New World (1992) is available for free download at the Internet Archive
- “The Political Force of Images,” Vistas: Visual Culture in Spanish America, 1520–1820.