Chinese biopharmaceutical company
This article is about the pharmaceutical company. For the COVID-19 vaccine that it developed, see
CoronaVac .
40°01′52″N 116°18′01″E / 40.031°N 116.3003°E / 40.031; 116.3003
Sinovac Biotech
Company type
Public
Nasdaq : SVA Founded 1999; 25 years ago (1999 ) Founder Yin Weidong
[1] Headquarters 39 Shang Di West Road, Haidian District, , China
Number of employees
4,281 (as of 2022)
[2]
Simplified Chinese 科兴控股生物技术有限公司
Traditional Chinese 科興控股生物技術有限公司 Literal meaning Kexing Holdings Biotechnology Co., Ltd. Transcriptions
Hanyu Pinyin Kē Xìng Kònggǔ Shēngwù Jìshù Yǒuxiàn Gōngsī
Website
www .sinovac .com
Sinovac Biotech Ltd. (
Chinese : 科兴控股生物技术有限公司 ) is a Chinese
biopharmaceutical company based in
Haidian District ,
Beijing that focuses on the research, development, manufacture, and
commercialization of
vaccines that protect against
human
infectious diseases . The company was listed on the
Nasdaq but the exchange halted Sinovac's trading in February 2019 due to a
proxy fight .
[3]
[4] The company has faced bribery probes in China.
[3]
Vaccines
Sinovac's commercialized vaccines include
CoronaVac (
COVID-19 vaccine ), Inlive (
Enterovirus 71 vaccine), Anflu (
influenza vaccine), Healive (
hepatitis A vaccine),
varicella vaccine and
mumps vaccine.
[5]
COVID-19 vaccine development
CoronaVac is an
inactivated virus COVID-19 vaccine developed by Sinovac.
[6] It has been in
Phase III clinical trials in
Brazil ,
[7]
Chile ,
[8]
Indonesia ,
[9]
Philippines ,
[10] and
Turkey .
[11]
It relies on traditional technology similar to the
Sinopharm BIBP vaccine and
Covaxin , otherwise known as inactivated-virus COVID-19 vaccines in Phase III trials.
[12] CoronaVac does not need to be frozen, and both the vaccine and raw material for formulating the new doses could be transported and refrigerated at 2–8 °C (36–46 °F), temperatures at which flu vaccines are kept.
[13]
A real-world study of ten millions of Chileans who received CoronaVac found it 66% effective against symptomatic COVID-19, 88% against hospitalization, 90% against ICU admissions, and 86% against deaths.
[14] In Brazil, after 75% of the population in
Serrana, São Paulo received CoronaVac, preliminary results show deaths fell by 95%, hospitalizations by 86%, and symptomatic cases by 80%.
[15]
[16] In Indonesia, real world data from 128,290 healthcare workers showed 94% protection against symptomatic infection by the vaccine, beating results in clinical trials.
[17]
Phase III results from Turkey published in
The Lancet showed an efficacy of 84% based on 10,218 participants in the trials.
[18]
[19] Phase III results from Brazil previously showed 50.7% efficacy at preventing symptomatic infections and 83.7% effective in preventing mild cases needing treatment. Efficacy against symptomatic infections increased to 62.3% with an interval of 21 days or more between the doses.
[20]
CoronaVac is being used in vaccination campaigns in various countries in Asia,
[21]
[22]
[23] South America,
[24]
[25]
[26] North America,
[27]
[28]
[29] and Europe.
[30]
[31]
[32] By April 2021, Sinovac had a production capacity of two billion doses a year
[33] and had delivered 600 million total doses.
[34] It is currently being manufactured at several facilities in China,
[33] Brazil,
[35] and Egypt.
[36] On 1 June 2021, the
World Health Organization (WHO) validated the vaccine for emergency use.
[37]
[38]
[39] Sinovac has signed purchase agreements for 380 million doses from
COVAX .
[40]
See also
References
^
"China's Vaccine Front-Runner Aims to Beat Covid the Old-Fashioned Way" . Bloomberg . 24 August 2020.
^
Submission Proof - tv479639
^
a
b Dou, Eva (December 4, 2020).
"As China nears a coronavirus vaccine, bribery cloud hangs over drugmaker Sinovac" .
The Washington Post .
ISSN
0190-8286 .
Archived from the original on December 4, 2020. Retrieved 2020-12-06 .
^ Levine, Matt (May 22, 2020).
"A Vaccine With a Poison Pill" .
Bloomberg News .
Archived from the original on June 21, 2020. Retrieved December 6, 2020 .
^
"Vaccines" . sinovac.com . Archived from
the original on 26 September 2021. Retrieved 1 September 2021 .
^ Nidhi Parekh (22 July 2020).
"CoronaVac: A COVID-19 Vaccine Made From Inactivated SARS-CoV-2 Virus" . Retrieved 25 July 2020 .
^
"New coronavirus vaccine trials start in Brazil" . AP News . 21 July 2020. Retrieved 2020-10-07 .
^
"Chile initiates clinical study for COVID-19 vaccine" . Chile Reports . 4 August 2020. Retrieved 2020-10-07 .
^
"248 volunteers have received Sinovac vaccine injections in Bandung" . Antara News . 30 August 2020. Retrieved 2020-10-07 .
^
"DOH eyes 5 hospitals for Sinovac vaccine Phase 3 clinical trial" . PTV News . 16 September 2020. Retrieved 2020-10-07 .
^
"Turkey begins phase three trials of Chinese Covid-19 vaccine" . TRT World News . 1 September 2020. Retrieved 2020-10-07 .
^ Zimmer, Carl; Corum, Jonathan; Wee, Sui-Lee (10 June 2020).
"Coronavirus Vaccine Tracker" . The New York Times .
ISSN
0362-4331 . Retrieved 2021-02-12 .
^
"CoronaVac: Doses will come from China on nine flights and can..." AlKhaleej Today (in Arabic). 2020-11-01. Retrieved 2021-02-12 .
^ Jara A, Undurraga EA, González C, Paredes F, Fontecilla T, Jara G, et al. (July 2021).
"Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile" . The New England Journal of Medicine . 385 (10): 875–884.
doi :
10.1056/NEJMoa2107715 .
PMC
8279092 .
PMID
34233097 .
S2CID
235766915 .
^ Savarese M (2021-06-01).
"Sinovac vaccine restores a Brazilian city to near normal" . CTV News . Retrieved 2021-06-02 .
^ Pearson S (2021-05-31).
"Brazil's Experiment to Vaccinate Town With Chinese CoronaVac Reduced Covid-19 Deaths by 95%" .
The Wall Street Journal .
ISSN
0099-9660 . Retrieved 2021-06-02 .
^
"China Sinovac Shot Seen Highly Effective in Real World Study" .
Bloomberg News . 3 June 2023. Retrieved 3 June 2023 .
^ Tanriover MD, Doğanay HL, Akova M, Güner HR, Azap A, Akhan S, et al. (8 July 2021).
"Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey" . The Lancet . 398 (10296): 213–222.
doi :
10.1016/S0140-6736(21)01429-X .
ISSN
0140-6736 .
PMC
8266301 .
PMID
34246358 .
S2CID
235770533 .
^
Evidence Assessment: Sinovac/CoronaVac COVID-19 vaccine (PDF) (Presentation). World Health Organization. 29 April 2021. Retrieved 10 July 2021 .
^ Costa A (2021-04-11).
"Estudo clínico que comprova maior eficácia da Coronavac é enviado para Lancet" [Clinical study proving greater efficacy of Coronavac is submitted to The Lancet]. CNN Brasil (in Portuguese). São Paulo. Retrieved 2021-04-12 .
^ TARIGAN, EDNA; MILKO, VICTORIA (13 January 2021).
"Indonesia starts mass COVID vaccinations over vast territory" .
Associated Press . Retrieved 15 January 2021 .
^
"Thailand Kicks Off Covid-19 Vaccine Program With Sinovac Shots" . Bloomberg.com . Retrieved 28 February 2021 .
^
"China approves Sinovac vaccines for general public use" . South China Morning Post . 6 February 2021. Retrieved 6 February 2021 .
^ Rochabrun, Marcelo.
"Brazil health ministry says plans to order 30 million more Coronavac doses | The Chronicle Herald" . www.thechronicleherald.ca . Retrieved 26 February 2021 .
^ Miranda, Natalia A. Ramos (28 January 2021).
"Chile receives two million-dose first delivery of Sinovac COVID-19 vaccine" . Reuters . Retrieved 30 January 2021 .
^
"BNamericas - Uruguay prepares to launch COVID-19 vaccinat..." BNamericas.com . Retrieved 1 March 2021 .
^
"Venustiano Carranza next up for Covid vaccination in Mexico City" . Mexico News Daily . 2021-03-15. Retrieved 2021-03-16 .
^
"Anticovid vaccines run out as Dominican Republic awaits arrival of more doses" . Dominican Today . Retrieved 2021-03-10 .
^
"Llegan a El Salvador un millón de dosis de la vacuna china CoronaVac contra el covid-19 de la farmacéutica Sinovac" . Noticias de El Salvador - La Prensa Gráfica | Informate con la verdad (in European Spanish). Retrieved 2021-03-28 .
^
"Turkey aims to vaccinate 60 percent of population: Minister – Turkey News" . Hürriyet Daily News . 11 February 2021. Retrieved 12 February 2021 .
^
"Vaccination with CoronaVac launched in Ukraine on April 13 – Health minister" . www.unian.info . Retrieved 2021-04-15 .
^ Semini, Llazar.
"Albania starts mass COVID vaccinations before tourist season" . ABC News . Retrieved 2021-03-28 .
^
a
b Liu, Roxanne (2021-04-02).
"China Sinovac says it reached two billion doses annual capacity for COVID-19 vaccine" . Reuters . Retrieved 2021-04-02 .
^ Nebehay, Stephanie (2021-06-01).
"WHO approves Sinovac COVID vaccine, the second Chinese-made dose listed" . Reuters . Geneva. Retrieved 2021-06-01 .
^ Mano A, Simões (10 December 2020).
"Chinese vaccine draws demand across Latin America, say Brazilian officials" . Reuters .
Archived from the original on 10 December 2020. Retrieved 10 December 2020 .
^
"Egypt to produce up to 80 million Sinovac vaccine doses annually" . Arab News . 2021-04-08. Retrieved 2021-04-08 .
^ Nebehay S (2021-06-01).
"WHO approves Sinovac COVID vaccine, the second Chinese-made dose listed" . Reuters . Geneva. Retrieved 2021-06-01 .
^
"WHO recommendation Sinovac COVID-19 vaccine (Vero Cell [Inactivated]) – CoronaVac" .
World Health Organization (WHO) . 1 May 2021. Archived from
the original on 2 June 2021. Retrieved 1 June 2021 .
^
"WHO validates Sinovac COVID-19 vaccine for emergency use and issues interim policy recommendations" .
World Health Organization (WHO) (Press release). Retrieved 1 June 2021 .
^
"Chinese drugmakers agree to supply more than half a billion vaccines to COVAX" . Reuters . 2021-07-12. Retrieved 2021-07-13 .
External links