From Wikipedia, the free encyclopedia
Species of bacterium
Salinispora tropica is an obligate marine actinomycete bacterium species.
[1] It produces
salinosporamide A and
salinosporamide B , potential anti-cancer agents,
[2]
[3] as well as the polycyclic
macrolides
sporolide A and B .
[4]
See also
References
^
a
b Maldonado, L. A. (2005).
"Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae " . International Journal of Systematic and Evolutionary Microbiology . 55 (5): 1759–1766.
doi :
10.1099/ijs.0.63625-0 .
ISSN
1466-5026 .
PMID
16166663 .
^ Fenical, W.; Jensen, P.R.; Palladino, M.A.; Lam, K.S.; Lloyd, G.K.; Potts, B.C. (2009).
"Discovery and development of the anticancer agent salinosporamide A (NPI-0052)" . Bioorganic & Medicinal Chemistry . 17 (6): 2175–2180.
doi :
10.1016/j.bmc.2008.10.075 .
PMC
2814440 .
PMID
19022674 .
^ Williams PG; Buchanan GO; Feling RH; Kauffman CA; Jensen PR; Fenical W (August 2005). "New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica".
The Journal of Organic Chemistry . 70 (16): 6196–203.
doi :
10.1021/jo050511+ .
PMID
16050677 .
^ Buchanan, Greg O.; Williams, Philip G.; Feling, Robert H.; Kauffman, Christopher A.; Jensen, Paul R.; Fenical, William (2005). "Sporolides a and b: Structurally Unprecedented Halogenated Macrolides from the Marine Actinomycete Salinispora tropica ". Organic Letters . 7 (13): 2731–2734.
doi :
10.1021/ol050901i .
PMID
15957933 .
Further reading
Udwary DW, Zeigler L, Asolkar RN, et al. (June 2007).
"Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica " .
Proceedings of the National Academy of Sciences of the United States of America . 104 (25): 10376–81.
Bibcode :
2007PNAS..10410376U .
doi :
10.1073/pnas.0700962104 .
PMC
1965521 .
PMID
17563368 .
Bucarey, S. A.; Penn, K.; Paul, L.; Fenical, W.; Jensen, P. R. (2012).
"Genetic Complementation of the Obligate Marine Actinobacterium Salinispora tropica with the Large Mechanosensitive Channel Gene mscL Rescues Cells from Osmotic Downshock" . Applied and Environmental Microbiology . 78 (12): 4175–4182.
doi :
10.1128/AEM.00577-12 .
ISSN
0099-2240 .
PMC
3370544 .
PMID
22492446 .
Thuan, Nguyen Huy; Yamaguchi, Tokutaro; Lee, Joo Ho; Sohng, Jae Kyung (2013). "Characterization of sterol glucosyltransferase from Salinispora tropica CNB-440: Potential enzyme for the biosynthesis of sitosteryl glucoside". Enzyme and Microbial Technology . 52 (4–5): 234–240.
doi :
10.1016/j.enzmictec.2013.02.004 .
ISSN
0141-0229 .
PMID
23540924 .
External links