The Salem River in Salem in 2006
|• location||Upper Pittsgrove Township|
|boundary of Pennsville and Elsinboro townships|
Latitude and Longitude:
|0 ft (0 m) |
|Length||35 mi (56 km) |
|Basin size||110 sq mi (280 km2)plus |
The course and watershed of the Salem River are entirely within Salem County. Tributaries of the Salem include Game Creek, Mannington Creek, and Fenwick Creek.  The river rises in Upper Pittsgrove Township and flows initially westwardly, through Pilesgrove Township and the borough of Woodstown and along the boundaries of Carneys Point and Mannington Townships. Near Deepwater it approaches to within 2 miles (3 km) of the Delaware River, a distance breached by the Salem (Deepwater) Canal, which connects the two rivers. From there the Salem River turns to the south, flowing along the boundary of Mannington and Pennsville Townships,  where it widens into a meandering shallow estuary, Kates Creek Meadow, and passes the city of Salem, its head of navigability.  It flows into the Delaware River from the east near the head of Delaware Bay, on the boundary of Pennsville and Elsinboro townships, approximately 2 miles (3 km) west of Salem and approximately 5 miles (8 km) southeast of Finns Point.
The Delaware and the Salem are tidal. The Delaware River Main Channel is maintained at a depth of 40 feet (12 m) and expected to be 45 feet (14 m) in 2017  Reach D, which includes the entrance to Port of Salem, was completed in 2010.  The shipping channel of the Salem River is much shallower, making the city a low draft port, which prohibits use by Handymax class ships. The river is entered though Salem Cove about 50 miles (80 km) from the entrance of the Delaware Bay. The channel travels along the southeast side of the cove for 2 miles (3.2 km) and continues another 3 miles (4.8 km) upstream of the first vehicular bridge crossing it.  The Salem River and Cut-Off was first channelized in 1925 to a depth of 16 feet (4.9 m). 
According to the Geographic Names Information System, the river has also been known historically as Firkins Creek, Varkens Kill, and Varkins Kill (Hogg Creek). The Board on Geographic Names settled on "Salem River" as the stream's name in 1940.  The estuary was inhabited by Lenape at the time of European colonization. In 1641, Emigrants from the New Haven Colony settled along the Varkens Kill. Fort Elfsborg, a settlement of the New Sweden colony was constructed along the eastern bank of the Delaware near the mouth of the Salem in 1642–1643. The fort was later abandoned because of the prevalence of mosquitoes and the construction of Fort Casimir by the New Netherland Dutch across the river. In 1675, the village of Salem was founded near the mouth of the Salem river as part of the Fenwick Colony. 
- "Geographic Names Information System entry for Salem River". Retrieved 2007-01-14.
- U.S. Geological Survey. National Hydrography Dataset high-resolution flowline data. The National Map, accessed April 1, 2011
- Rutgers Cooperative Research & Extension Water Resources Program; The Cumberland Salem Conservation District; Rutgers Cooperative & Extension of Salem County. "Watershed Restoration Plan for the Upper Salem River Watershed: Phase 1" (PDF). pp. p. 7. Retrieved 2007-01-14.
- DeLorme (2005). New Jersey Atlas & Gazetteer. Yarmouth, Maine: DeLorme. ISBN 0-89933-324-9.
- "Columbia Gazetteer of North America entry for Salem River". Archived from the original on 2005-03-12. Retrieved 2007-01-14.
- "Delaware River Main Channel Deepening". United States Army Corps of Engineers. Retrieved 2013-07-25.
- "Contract 1 Reach D" (PDF). US Army Corps of Engineers. Retrieved 2013-07-31.
- Griffes, Peter L. Griffes (2004). (148) Salem River. Atlantic Boating Almanac 2004. ProStar Publications. ISBN 9781577855033.
- "Salem River". US Army Corps of Engineers. April 2013. Retrieved 2013-07-31.
- "Historic Roadsides of New Jersey". Retrieved 2007-01-14.