Jacques Raphaël Lépine (6 July 1840 – 17 November 1919) was a French
physiologist who was a native of
Lyon.
Biography
From 1860 he served as interne to the hospitals of Lyon, and later moved to
Paris, where from 1865 he also worked as a hospital intern. In Paris he was a student of
Jean-Martin Charcot (1825–1893). Afterwards, he continued his education at the universities of
Berlin (1867) and
Leipzig (1869). At
Karl Ludwig's laboratory in
Leipzig he performed important studies on the
vasomotor nerves of the
tongue.
In 1870 he obtained his doctorate in Paris with a dissertation titled "De l'hémiplégie pneumonique". In Paris he successively became chef de clinique (1872), médecin des hôpitaux (1874) and
agrégé at the Paris faculty (1875). In 1877 he was appointed professor at the medical clinic of the newly established medical faculty in Lyons.
He was the brother of
Louis Lépine, Prefect of Police for the Seine from 1893 to 1897 and again from 1899 to 1913.
Selected writings
Sur un cas d'abcès d'un des lobes antérieurs du cerveau; Abscess of the
anterior lobes of the brain
De l'hémiplégie pneumonique (1870) --- On pneumonic
hemiplegia
De la localisation dans les maladies cérébrales (1875) --- Localization in brain diseases
Additions à la traduction francaise du Traité des maladies des reins de Bartels (1884) --- Additions to the French translation of the treatise on
kidney diseases by
Karl Heinrich Christian Bartels.
Le Ferment glycolytique et la pathogénie du diabète (1891) --- The glycolytic ferment and pathogenesis of diabetes
Influence de la faradisation des nerfs du pancréas sur la glycolyse (1899)
Le diabète et son traitement (1899) --- Diabetes and its treatment
Le diabète non compliqué et son traitement (1905)
Les complications du diabète et leur traitement (1906) --- Diabetic complications and treatment
Le Sucre virtuel du sang (1910) with R. Boulud --- The virtual
blood sugar
Sur la résorption du sucre par les tubes du rein (1911) --- On the absorption of sugar by the tubes of the
kidney.[2]