The marginal nucleus of spinal cord, or posteromarginal nucleus,
Rexed lamina I, is located at the most dorsal aspect of the
dorsal horn of the
spinal cord. The
neurons located here receive input primarily from
Lissauer's tract and relay information related to
pain and
temperature sensation.[1][2] Pain sensation relayed here cannot be modulated, e.g. pain from burning the skin.
The axons of neurons contribute to the lateral spinothalamic tract.[3][4]