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For Liu Ping, see Liu Ping (disambiguation)
Ping Liu
Born1964 (age 59–60)
Academic background
Alma mater Anhui University, University of Otago
Thesis
Doctoral advisorDavid Bilkey
Academic work
Institutions University of Otago

Ping Liu (born 1964) [1] is a Chinese New Zealand academic, and is a full professor at the University of Otago, specialising in neurobiology, especially how arginine metabolism affects brain function in normal ageing and in diseases such as schizophrenia and Alzheimer's disease.

Academic career

Liu is a neurobiologist with a medical background. She completed an MB at Anhui University and then worked for eight years as a geriatrician in China before joining her husband in New Zealand, where he had studied. [2] Liu realised that working as a doctor in New Zealand would be difficult due to the language barrier, so made the decision to retrain as a researcher. [2] She joined the staff of the University of Otago in 1994, [3] and began a PhD in the Department of Psychology, supervised by David Bilkey, the following year. [2] She completed her doctoral thesis, titled Perirhinal cortex contributions to spatial memory in 1998, [1] and rose to full professor in 2020. [4] She is part of the Otago's Brain Health Research Centre. [5]

Liu's research focuses on neurodegenerative disorders such as schizophrenia and Alzheimer's disease, and on the changes in memory, learning and brain metabolism during normal ageing. [4] Liu investigates the metabolic products of the semi-essential amino acid arginine. Liu's research has shown that altered arginine metabolism is associated with both schizophrenia and Alzheimer's disease. One metabolic product of arginine, agmatine, is a possible new neurotransmitter, but its role in learning and memory is as yet poorly understood. [6] Liu's research group uses animal models and post-mortem human brain tissue to investigate how these changed processes lead to disease, and to try to identify possible diagnostic tests and therapeutic targets. [7] In particular, Liu believes that arginine metabolites might present a less-invasive and costly test for Alzheimer's disease than the present diagnostic tests of brain scans and cerebrospinal fluid testing. It might also be possible to diagnose people earlier through such biomarkers. [7] Liu is also investigating whether arginine metabolism differences might be involved in the clinical differences seen between early and late-onset Alzheimer's disease. [7]

Liu's group is also researching the effects of prenatal viral exposure in children. [2]

Selected works

Scholia has a profile for Ping Liu (Q91759573).
  • John E Piletz; Feyza Aricioglu; Juei-Tang Cheng; et al. (13 June 2013). "Agmatine: clinical applications after 100 years in translation". Drug Discovery Today. 18 (17–18): 880–893. doi: 10.1016/J.DRUDIS.2013.05.017. ISSN  1359-6446. PMID  23769988. Wikidata  Q34351125.
  • Ping Liu; Michael S Fleete; Yu Jing; et al. (20 March 2014). "Altered arginine metabolism in Alzheimer's disease brains". Neurobiology of Aging. 35 (9): 1992–2003. doi: 10.1016/J.NEUROBIOLAGING.2014.03.013. ISSN  0197-4580. PMID  24746363. Wikidata  Q53463642.
  • Ping Liu; David Bilkey (1 February 2001). "The effect of excitotoxic lesions centered on the hippocampus or perirhinal cortex in object recognition and spatial memory tasks". Behavioral Neuroscience. 115 (1): 94–111. doi: 10.1037/0735-7044.115.1.94. ISSN  0735-7044. PMID  11256456. Wikidata  Q33938704.
  • Ping Liu; David Bilkey (1 April 1998). "Perirhinal cortex contributions to performance in the Morris water maze". Behavioral Neuroscience (in English and English). 112 (2): 304–315. doi: 10.1037/0735-7044.112.2.304. ISSN  0735-7044. PMID  9588480. Wikidata  Q34468208.
  • Ping Liu; Paul F Smith; Cynthia L Darlington (1 November 2008). "Glutamate receptor subunits expression in memory-associated brain structures: regional variations and effects of aging". Synapse. 62 (11): 834–841. doi: 10.1002/SYN.20563. ISSN  0887-4476. PMID  18720514. Wikidata  Q46416264.
  • Jiaxian Zhang; Yu Jing; Hu Zhang; Ping Liu (10 July 2021). "Effects of sex and estrous cycle on the brain and plasma arginine metabolic profile in rats" (PDF). Amino Acids. 53 (9): 1441–1454. doi: 10.1007/S00726-021-03040-5. ISSN  0939-4451. Wikidata  Q124094902.
  • Faraz Ahmad; Ping Liu (3 June 2021). "A Time-Efficient Fluorescence Spectroscopy-Based Assay for Evaluating Actin Polymerization Status in Rodent and Human Brain Tissues". Journal of Visualized Experiments (172). doi: 10.3791/62268. ISSN  1940-087X. Wikidata  Q124094903.

References

  1. ^ a b Liu, Ping (1998). Perirhinal cortex contributions to spatial memory (PhD thesis). University of Otago. Retrieved 5 January 2024.
  2. ^ a b c d Nealon, Kelly (20 April 2022). "Celebrating Chinese Language Day". Inside Government NZ. Retrieved 3 January 2024.
  3. ^ "University staff". The University of Otago Calendar for 2022 (PDF). p. 49. Retrieved 5 January 2024.
  4. ^ a b Otago Bulletin Board (8 December 2020). "Otago announces 26 new professors". www.otago.ac.nz. Retrieved 3 January 2024.
  5. ^ Brain Health Research Centre (2 February 2021). "Professor Ping Liu". testwww.otago.ac.nz. Retrieved 3 January 2024.
  6. ^ Brain Health Research Centre (2 February 2021). "Professor Ping Liu". www.otago.ac.nz. Retrieved 3 January 2024.
  7. ^ a b c Brain Research New Zealand (9 August 2020). "Assoc Prof Ping Liu: Detecting Alzheimer's through targeted metabolomics". Brain Research New Zealand. Retrieved 3 January 2024.
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