Academy for Radiology & Biomedical Imaging Research: 2019 Distinguished Investigator Award; Society of Nuclear Medicine and Molecular Imaging: 2023 Sam Gambhir Trailblazer Award.
Peter J. H. ScottFRSCCChem (born July 27, 1979) is a British and American chemist and radiochemist who is a professor of radiology, professor of pharmacology and professor of medicinal chemistry, as well as a core member of the
Rogel Cancer Center at the
University of Michigan in the United States.[1][2] He is Chief of Nuclear Medicine and director of the University of Michigan Positron Emission Tomography (
PET) Center,[3] and runs a research group developing new
radiochemistry methodology and novel PET
radiotracers.[4]
Life
Peter Scott was born and grew up in North East England and attended
Whitley Bay High School. He received his undergraduate degree with
first class honors in medicinal and pharmaceutical chemistry from
Loughborough University in 2001, after conducting research with Raymond Jones. He subsequently obtained his PhD in organic chemistry from
Durham University in 2005, where he was a member of
Ustinov College, under the mentorship of Patrick G. Steel. Scott then moved to the United States to undertake postdoctoral research in organometallic chemistry at
SUNY Buffalo under
Huw Davies, and PET radiochemistry at the University of Michigan with Michael Kilbourn.
Research
Scott runs a research group developing new metal-catalyzed methods for incorporating
fluorine-18 and
carbon-11 into bioactive molecules as well as novel PET
radiotracers for imaging
neurodegenerative disorders. His methodology work aims to improve the synthesis of PET radiotracers and he has an active collaboration with
Prof. Melanie Sanford's group[5] that is funded by
NIBIB.[6] Together they have developed methods for the Cu-mediated
radiofluorination[7] and radiocyanation of (mesityl)(aryl)iodonium salts,[8] boronic acids[9][10] and stannanes,[10][11] as well as new methods for radiofluorination of C-H bonds[12][13][14] and aryl halides.[15] Scott has also introduced methods for green radiochemistry,[16] for which he received the Michigan
Green Chemistry Governor's Award in 2014.[17] In 2019, Prof. Scott was elected as a Fellow of the
Royal Society of Chemistry (
FRSC),[18] and received a Distinguished Investigator Award from the Academy for Radiology & Biomedical Imaging Research.[19] In 2021, he was honored as a Fellow of the
Society of Nuclear Medicine and Molecular Imaging,[20] and was also recognized by SNMMI in 2023 with the Sam Gambhir Trailblazer Award,[21] created to honor the legacy and memory of the late
Sanjiv Sam Gambhir.
Bibliography
1. Linker Strategies in Solid-phase Organic Synthesis (Editor, 2009)[22] 2. Solid-Phase Organic Syntheses, Volume 2: Solid-Phase Palladium Chemistry (Wiley Series on Solid-Phase Organic Syntheses) (Editor, 2012)[23] 3. Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1 (Editor, 2012)[24] 4. Radiochemical Syntheses: Further Radiopharmaceuticals for Positron Emission Tomography and New Strategies for Their Production, Volume 2 (Editor, 2015)[25] 5. Handbook of Radiopharmaceuticals (2nd Edition): Methodology and Applications (Editor, 2021)[26] 6. Production and Quality Control of Fluorine-18 Labelled Radiopharmaceuticals (co-authored with
International Atomic Energy Agency, 2021) [27]
^Stewart, Megan N.; Hockley, Brian G.; Scott, Peter J. H. (2015). "Green approaches to late-stage fluorination: radiosyntheses of 18F-labelled radiopharmaceuticals in ethanol and water". Chemical Communications. 51 (79): 14805–14808.
doi:
10.1039/c5cc05919d.
ISSN1359-7345.
PMID26300287.