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The Penikese Island Leper Hospital was a leprosy hospital located on Penikese Island, off the coast of Massachusetts, United States, from 1905 to 1921. It housed a small colony of people who suffered from leprosy over the years until it was closed in 1921 and patients were relocated to a federal hospital in Louisiana.
41°27′4″N 70°55′29″W / 41.45111°N 70.92472°W