From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
PH domain and leucine rich repeat protein phosphatase-like, also known as PHLPPL, is an
enzyme which in humans is encoded by the PHLPPL
gene.
[5]
See also
References
Further reading
- Nagase T, Ishikawa K, Suyama M, et al. (1999).
"Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70.
doi:
10.1093/dnares/6.1.63.
PMID
10231032.
- Hartley JL, Temple GF, Brasch MA (2001).
"DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95.
doi:
10.1101/gr.143000.
PMC
310948.
PMID
11076863.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001).
"Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35.
doi:
10.1101/gr.GR1547R.
PMC
311072.
PMID
11230166.
- Simpson JC, Wellenreuther R, Poustka A, et al. (2001).
"Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92.
doi:
10.1093/embo-reports/kvd058.
PMC
1083732.
PMID
11256614.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.
Bibcode:
2002PNAS...9916899M.
doi:
10.1073/pnas.242603899.
PMC
139241.
PMID
12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5.
doi:
10.1038/ng1285.
PMID
14702039.
- Wiemann S, Arlt D, Huber W, et al. (2004).
"From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44.
doi:
10.1101/gr.2576704.
PMC
528930.
PMID
15489336.
- Martin J, Han C, Gordon LA, et al. (2005).
"The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–94.
Bibcode:
2004Natur.432..988M.
doi:
10.1038/nature03187.
PMID
15616553.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006).
"The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8.
doi:
10.1093/nar/gkj139.
PMC
1347501.
PMID
16381901.
- Brognard J, Sierecki E, Gao T, Newton AC (2007).
"PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms". Mol. Cell. 25 (6): 917–31.
doi:
10.1016/j.molcel.2007.02.017.
PMID
17386267.
- Rizvi F, Shukla S, Kakkar P (2014).
"Essential role of PH domain and leucine-rich repeat protein phosphatase 2 in Nrf2 suppression via modulation of Akt/GSK3β/Fyn kinase axis during oxidative hepatocellular toxicity". Cell Death Dis. 5 (3): e1153.
doi:
10.1038/cddis.2014.118.
PMC
3973230.
PMID
24675471.