Protocadherin-1 is a
protein that in humans is encoded by the PCDH1gene.[5][6]
This gene belongs to the
protocadherin subfamily within the
cadherin superfamily. The encoded protein is a
membrane protein found at cell-cell boundaries. It is involved in
neural cell adhesion, suggesting a possible role in neuronal development. The protein includes an extracellular region, containing 7 cadherin-like domains, a transmembrane region and a
C-terminal cytoplasmic region. Cells expressing the protein showed cell aggregation activity.
Alternative splicing occurs in this gene.[6]
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Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101.
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10.1038/nbt1046.
PMID15592455.
S2CID7200157.