PATCO may refer to:
- Professional Air Traffic Controllers Organization (1968), the defunct American labor union of air traffic controllers; famous for its failed 1981 strike
- Professional Air Traffic Controllers Organization (2003), an independent labor union in the United States
- Professional Air Traffic Controllers Organization (AFSCME), an affiliate of the American Federation of State, County and Municipal Employees (AFSCME)
- PATCO Speedline, a rapid transit system running between Philadelphia, Pennsylvania and Camden County, New Jersey
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disambiguation page lists articles associated with the title PATCO.
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