Clinical data | |
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Other names | ASP-1707 |
Routes of administration | By mouth |
Drug class | GnRH modulator; GnRH antagonist; Antigonadotropin |
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Chemical and physical data | |
Formula | C25H19F3N4O5S |
Molar mass | 544.51 g·mol−1 |
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Opigolix ( INN , USAN ; developmental code name ASP-1707) is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which was under development by Astellas Pharma for the treatment of endometriosis and rheumatoid arthritis. [1] [2] It was also under investigation for the treatment of prostate cancer. [1] It reached phase II clinical trials for both endometriosis and rheumatoid arthritis prior to the discontinuation of its development in April 2018. [1]