From Wikipedia, the free encyclopedia
Oleclumab
Monoclonal antibody
Type?
Source Human
Target 5'-nucleotidase NT5E
Clinical data
Other namesMEDI9447
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6348H9826N1710O1998S40
Molar mass143350.81 g·mol−1

Oleclumab ( INN; [1] development code MEDI9447) is a human monoclonal antibody targeting the ectonucleotidase CD73 that was designed for the treatment of pancreatic and colorectal and other cancers. [2]

This drug was developed by MedImmune/ AstraZeneca. [3]

References

  1. ^ World Health Organization (2016). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 116" (PDF). WHO Drug Information. 30 (4).
  2. ^ ClinicalTrial.gov for Oleclumab
  3. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Oleclumab, American Medical Association.