From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Olfactory receptor 7A17 is a
protein that in humans is encoded by the OR7A17
gene .
[5]
[6]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
[6]
See also
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000185385 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000048101 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature . 355 (6359): 453–5.
Bibcode :
1992Natur.355..453P .
doi :
10.1038/355453a0 .
PMID
1370859 .
S2CID
43926 .
^
a
b
"Entrez Gene: OR7A17 olfactory receptor, family 7, subfamily A, member 17" .
Further reading
Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics . 80 (3): 295–302.
CiteSeerX
10.1.1.135.3652 .
doi :
10.1006/geno.2002.6830 .
PMID
12213199 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Malnic B, Godfrey PA, Buck LB (2004).
"The human olfactory receptor gene family" . Proc. Natl. Acad. Sci. U.S.A . 101 (8): 2584–9.
Bibcode :
2004PNAS..101.2584M .
doi :
10.1073/pnas.0307882100 .
PMC
356993 .
PMID
14983052 .
Grimwood J, Gordon LA, Olsen A, et al. (2004).
"The DNA sequence and biology of human chromosome 19" . Nature . 428 (6982): 529–35.
Bibcode :
2004Natur.428..529G .
doi :
10.1038/nature02399 .
PMID
15057824 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
External links
This article incorporates text from the
United States National Library of Medicine , which is in the
public domain .
Class I (fish-like receptors)
Family 51 Family 52 Family 56
Class II (
tetrapod specific receptors)
Family 1 Family 2 Family 3 Family 4 Family 5 Family 6 Family 7 Family 8 Family 9 Family 10 Family 11 Family 12 Family 13